(108 nodes) Apical part of cell network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_08964	Ras family protein. (197 aa)
	NECAME_09497	Uncharacterized protein. (87 aa)
	NECAME_02308	PDZ/DHR/GLGF domain protein. (507 aa)
	NECAME_09208	Metal cation transporter, ZIP family. (426 aa)
	NECAME_18008	Uncharacterized protein. (155 aa)
	NECAME_02643	PDZ domain-containing protein. (213 aa)
	NECAME_15169	Kinase domain protein; Belongs to the protein kinase superfamily. (416 aa)
	NECAME_15168	Uncharacterized protein. (226 aa)
	NECAME_01116	Uncharacterized protein. (386 aa)
	NECAME_14684	7 transmembrane receptor. (424 aa)
	NECAME_15058	ADP-ribosylation factor family protein; Belongs to the small GTPase superfamily. Arf family. (175 aa)
	NECAME_00483	PAN domain protein. (738 aa)
	NECAME_00526	TROVE domain protein. (634 aa)
	NECAME_14517	Organic solute transporter alpha-like protein C18A3.4 family protein. (334 aa)
	NECAME_12048	Receptor L domain protein. (454 aa)
	NECAME_03634	ZP domain-containing protein. (256 aa)
	NECAME_00375	Phosphoglycolate/pyridoxal phosphate phosphatase family protein; Belongs to the HAD-like hydrolase superfamily. (274 aa)
	NECAME_02642	PDZ/DHR/GLGF domain protein. (389 aa)
	NECAME_10331	ATP synthase, subunit E. (226 aa)
	NECAME_09863	FG-GAP repeat protein. (338 aa)
	NECAME_12002	Ferlin_C domain-containing protein. (383 aa)
	NECAME_14444	Uncharacterized protein. (135 aa)
	NECAME_14601	RhoGAP domain protein. (587 aa)
	NECAME_14170	Uncharacterized protein. (243 aa)
	NECAME_14445	Uncharacterized protein. (190 aa)
	NECAME_19134	Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (103 aa)
	NECAME_10132	Uncharacterized protein. (96 aa)
	NECAME_10458	Amino acid permease. (925 aa)
	NECAME_03297	Uncharacterized protein. (132 aa)
	NECAME_03296	Uncharacterized protein. (154 aa)
	NECAME_10996	Ankyrin repeat protein. (552 aa)
	NECAME_03294	Uncharacterized protein. (182 aa)
	NECAME_03244	Kinase domain protein. (331 aa)
	NECAME_03298	Uncharacterized protein. (270 aa)
	NECAME_03243	Uncharacterized protein. (143 aa)
	NECAME_03295	Uncharacterized protein. (292 aa)
	NECAME_19537	Uncharacterized protein. (151 aa)
	NECAME_06422	Zona pellucida-like domain protein. (291 aa)
	NECAME_16657	Uncharacterized protein. (105 aa)
	NECAME_16900	MFS domain-containing protein. (69 aa)
	NECAME_16656	Putative permease. (283 aa)
	NECAME_04514	Uncharacterized protein. (131 aa)
	NECAME_04515	Uncharacterized protein. (68 aa)
	NECAME_19099	Uncharacterized protein. (201 aa)
	NECAME_13974	Inositol transporter 4 domain protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (391 aa)
	NECAME_01492	ABC transporter, ATP-binding protein. (308 aa)
	NECAME_01491	ABC transmembrane type-1 domain-containing protein. (167 aa)
	NECAME_18665	Uncharacterized protein. (162 aa)
	NECAME_06165	Trypsin Inhibitor like cysteine rich domain protein. (108 aa)
	NECAME_16968	Uncharacterized protein. (263 aa)
	NECAME_17069	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1063 aa)
	NECAME_01493	ABC transporter, ATP-binding protein. (389 aa)
	NECAME_16978	Renin receptor-like protein. (324 aa)
	NECAME_17227	Uncharacterized protein. (278 aa)
	NECAME_17173	Uncharacterized protein. (88 aa)
	NECAME_16541	Uncharacterized protein. (218 aa)
	NECAME_01253	FERM central domain protein. (286 aa)
	NECAME_06030	Uncharacterized protein. (113 aa)
	NECAME_19530	Uncharacterized protein. (192 aa)
	NECAME_17174	Uncharacterized protein. (128 aa)
	NECAME_06007	Uncharacterized protein. (602 aa)
	NECAME_17650	MFS transporter, SP family; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
	NECAME_01922	EGF-like domain protein. (262 aa)
	NECAME_06162	Trypsin Inhibitor like cysteine rich domain protein. (154 aa)
	NECAME_05444	Zona pellucida-like domain protein. (302 aa)
	NECAME_15582	Ammonium transporter Rh type C domain protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (170 aa)
	NECAME_01118	Vang-like protein. (530 aa)
	NECAME_19511	Natural resistance-associated macrophage protein. (118 aa)
	NECAME_05683	Uncharacterized protein. (183 aa)
	NECAME_19476	Uncharacterized protein. (161 aa)
	NECAME_05501	Zona pellucida-like domain protein. (274 aa)
	NECAME_17543	Uncharacterized protein. (249 aa)
	NECAME_01921	EGF-like domain protein. (286 aa)
	NECAME_07590	Transcriptional Coactivator p15. (63 aa)
	NECAME_05502	Uncharacterized protein. (107 aa)
	NECAME_03632	PAN domain protein. (804 aa)
	NECAME_12087	Myotubularin phosphatase domain-containing protein. (735 aa)
	NECAME_12049	Receptor protein-tyrosine kinase. (618 aa)
	NECAME_03581	MFS transporter, SP family; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (516 aa)
	NECAME_03861	Oxidoreductase, short chain dehydrogenase/reductase family protein. (719 aa)
	NECAME_12951	Solute carrier family 23 member 1. (556 aa)
	NECAME_18481	Uncharacterized protein. (87 aa)
	NECAME_13564	Kinase domain protein; Belongs to the protein kinase superfamily. (298 aa)
	NECAME_18840	Uncharacterized protein. (65 aa)
	NECAME_04512	Uncharacterized protein. (324 aa)
	NECAME_13529	Calcium release-activated calcium channel protein 1 domain protein. (189 aa)
	NECAME_18397	Uncharacterized protein. (77 aa)
	NECAME_13167	Metal ion transporter, metal ion transporter family. (385 aa)
	NECAME_13133	Uncharacterized protein. (3217 aa)
	NECAME_13177	PH domain protein. (658 aa)
	NECAME_12995	Uncharacterized protein. (200 aa)
	NECAME_03995	Variant SH3 domain protein. (652 aa)
	NECAME_00764	Uncharacterized protein. (4359 aa)
	NECAME_03952	F-BAR domain-containing protein. (383 aa)
	NECAME_03978	Uncharacterized protein. (78 aa)
	NECAME_03977	Phosphotyrosine interaction domain protein. (300 aa)
	NECAME_13176	Uncharacterized protein. (135 aa)
	NECAME_03954	Phorbol-ester/DAG-type domain-containing protein. (164 aa)
	NECAME_13063	RhoGEF domain protein. (837 aa)
	NECAME_01919	Uncharacterized protein. (119 aa)
	NECAME_17667	Uncharacterized protein. (111 aa)
	NECAME_07910	Uncharacterized protein. (238 aa)
	NECAME_01920	EGF-like domain protein. (184 aa)
	NECAME_17893	Uncharacterized protein. (150 aa)
	NECAME_17668	Uncharacterized protein. (83 aa)
	NECAME_08031	Asparaginase. (326 aa)
	NECAME_18027	Uncharacterized protein. (155 aa)
	NECAME_02309	FERM central domain protein. (796 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_01118	NECAME_08964	W2SHH4	W2TG27	Vang-like protein.	Ras family protein.	0.578
NECAME_01253	NECAME_19530	W2TYE8	W2U0C9	FERM central domain protein.	Uncharacterized protein.	0.655
NECAME_01491	NECAME_01492	W2TV40	W2TV62	ABC transmembrane type-1 domain-containing protein.	ABC transporter, ATP-binding protein.	0.532
NECAME_01492	NECAME_01491	W2TV62	W2TV40	ABC transporter, ATP-binding protein.	ABC transmembrane type-1 domain-containing protein.	0.532
NECAME_01919	NECAME_01920	W2TLX1	W2TKL1	Uncharacterized protein.	EGF-like domain protein.	0.657
NECAME_01919	NECAME_01921	W2TLX1	W2TNC5	Uncharacterized protein.	EGF-like domain protein.	0.455
NECAME_01920	NECAME_01919	W2TKL1	W2TLX1	EGF-like domain protein.	Uncharacterized protein.	0.657
NECAME_01921	NECAME_01919	W2TNC5	W2TLX1	EGF-like domain protein.	Uncharacterized protein.	0.455
NECAME_02308	NECAME_02309	W2TFD9	W2TG34	PDZ/DHR/GLGF domain protein.	FERM central domain protein.	0.867
NECAME_02309	NECAME_02308	W2TG34	W2TFD9	FERM central domain protein.	PDZ/DHR/GLGF domain protein.	0.867
NECAME_03243	NECAME_03244	W2T5F4	W2T690	Uncharacterized protein.	Kinase domain protein.	0.433
NECAME_03244	NECAME_03243	W2T690	W2T5F4	Kinase domain protein.	Uncharacterized protein.	0.433
NECAME_03632	NECAME_03634	W2T2S3	W2T3R4	PAN domain protein.	ZP domain-containing protein.	0.852
NECAME_03634	NECAME_03632	W2T3R4	W2T2S3	ZP domain-containing protein.	PAN domain protein.	0.852
NECAME_03952	NECAME_03954	W2SXZ6	W2T053	F-BAR domain-containing protein.	Phorbol-ester/DAG-type domain-containing protein.	0.797
NECAME_03952	NECAME_08964	W2SXZ6	W2TG27	F-BAR domain-containing protein.	Ras family protein.	0.463
NECAME_03954	NECAME_03952	W2T053	W2SXZ6	Phorbol-ester/DAG-type domain-containing protein.	F-BAR domain-containing protein.	0.797
NECAME_03954	NECAME_08964	W2T053	W2TG27	Phorbol-ester/DAG-type domain-containing protein.	Ras family protein.	0.463
NECAME_03995	NECAME_12048	W2SXL8	W2T4N7	Variant SH3 domain protein.	Receptor L domain protein.	0.429
NECAME_03995	NECAME_12049	W2SXL8	W2T200	Variant SH3 domain protein.	Receptor protein-tyrosine kinase.	0.429