(36 nodes) Low-density lipoprotein (LDL) receptor class A repeat network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_04051	Low-density lipoprotein receptor domain class A. (186 aa)
	NECAME_00764	Uncharacterized protein. (4359 aa)
	NECAME_14114	Low-density lipoprotein receptor domain class A. (100 aa)
	NECAME_04570	Low-density lipoprotein receptor domain class A. (135 aa)
	NECAME_19094	Low-density lipoprotein receptor domain class A. (61 aa)
	NECAME_04602	Low-density lipoprotein receptor domain class A. (81 aa)
	NECAME_04671	Low-density lipoprotein receptor domain class A. (364 aa)
	NECAME_14367	Low-density lipoprotein receptor domain class A. (109 aa)
	NECAME_15144	Low-density lipoprotein receptor domain class A. (192 aa)
	NECAME_05166	CUB domain protein. (966 aa)
	NECAME_15145	Low-density lipoprotein receptor domain class A. (102 aa)
	NECAME_15147	Low-density lipoprotein receptor domain class A. (130 aa)
	NECAME_15141	Low-density lipoprotein receptor domain class A. (172 aa)
	NECAME_05635	Uncharacterized protein. (169 aa)
	NECAME_05634	Uncharacterized protein. (147 aa)
	NECAME_00065	Uncharacterized protein. (102 aa)
	NECAME_00063	Uncharacterized protein. (145 aa)
	NECAME_16285	Low-density lipoprotein receptor domain class A. (108 aa)
	NECAME_16519	EF-hand domain-containing protein. (433 aa)
	NECAME_05971	SCP-like protein. (950 aa)
	NECAME_05957	SCP-like protein. (570 aa)
	NECAME_17527	Low-density lipoprotein receptor domain class A. (188 aa)
	NECAME_07426	Low-density lipoprotein receptor domain class A. (912 aa)
	NECAME_08552	Low-density lipoprotein receptor repeat class B. (631 aa)
	NECAME_02266	Low-density lipoprotein receptor domain class A. (406 aa)
	NECAME_09131	Low-density lipoprotein receptor domain class A. (564 aa)
	NECAME_02247	Low-density lipoprotein receptor domain class A. (168 aa)
	NECAME_18043	Low-density lipoprotein receptor domain class A. (99 aa)
	NECAME_10315	Sushi domain protein. (1378 aa)
	NECAME_03212	Low-density lipoprotein receptor domain class A. (78 aa)
	NECAME_10800	Low-density lipoprotein receptor domain class A. (582 aa)
	NECAME_11519	Low-density lipoprotein receptor domain class A. (285 aa)
	NECAME_11514	Low-density lipoprotein receptor domain class A. (330 aa)
	NECAME_00675	Low-density lipoprotein receptor domain class A. (238 aa)
	NECAME_12242	Low-density lipoprotein receptor domain class A. (243 aa)
	NECAME_00674	Low-density lipoprotein receptor domain class A. (84 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_00675	NECAME_02266	W2T149	W2TIM7	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.477
NECAME_00675	NECAME_09131	W2T149	W2THL4	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.405
NECAME_00675	NECAME_15144	W2T149	W2SLX4	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.434
NECAME_02247	NECAME_11519	W2TGA6	W2T6N8	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.415
NECAME_02247	NECAME_15144	W2TGA6	W2SLX4	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.473
NECAME_02247	NECAME_15147	W2TGA6	W2SJE5	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.472
NECAME_02266	NECAME_00675	W2TIM7	W2T149	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.477
NECAME_02266	NECAME_11519	W2TIM7	W2T6N8	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.441
NECAME_02266	NECAME_15144	W2TIM7	W2SLX4	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.467
NECAME_02266	NECAME_18043	W2TIM7	W2TFZ1	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.431
NECAME_09131	NECAME_00675	W2THL4	W2T149	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.405
NECAME_11514	NECAME_11519	W2T6N2	W2T6N8	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.543
NECAME_11514	NECAME_15144	W2T6N2	W2SLX4	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.438
NECAME_11514	NECAME_15147	W2T6N2	W2SJE5	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.435
NECAME_11514	NECAME_18043	W2T6N2	W2TFZ1	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.604
NECAME_11519	NECAME_02247	W2T6N8	W2TGA6	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.415
NECAME_11519	NECAME_02266	W2T6N8	W2TIM7	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.441
NECAME_11519	NECAME_11514	W2T6N8	W2T6N2	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.543
NECAME_11519	NECAME_15144	W2T6N8	W2SLX4	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.492
NECAME_11519	NECAME_15147	W2T6N8	W2SJE5	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor domain class A.	0.474