(30 nodes) Six-bladed beta-propeller, TolB-like network (Necator americanus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NECAME_11519	Low-density lipoprotein receptor domain class A. (285 aa)
	NECAME_00981	Copper type II ascorbate-dependent monooxygenase domain protein. (784 aa)
	NECAME_14669	Uncharacterized protein. (109 aa)
	NECAME_14290	Strictosidine synthase. (384 aa)
	NECAME_19024	Uncharacterized protein. (35 aa)
	NECAME_13759	WD40-like protein. (698 aa)
	NECAME_04407	Peptidase, S9A/B/C family, catalytic domain protein. (640 aa)
	NECAME_13633	Uncharacterized protein. (90 aa)
	NECAME_18648	Uncharacterized protein. (183 aa)
	NECAME_13632	Uncharacterized protein. (52 aa)
	NECAME_00764	Uncharacterized protein. (4359 aa)
	NECAME_04040	Zinc finger, C3HC4 type. (1006 aa)
	NECAME_03483	B-box zinc finger. (843 aa)
	NECAME_03452	Uncharacterized protein. (274 aa)
	NECAME_11517	Low-density lipoprotein receptor repeat class B. (312 aa)
	NECAME_11515	Uncharacterized protein. (184 aa)
	NECAME_11520	Uncharacterized protein. (329 aa)
	NECAME_03451	Uncharacterized protein. (253 aa)
	NECAME_11516	Uncharacterized protein. (156 aa)
	NECAME_11513	EGF-like domain-containing protein. (301 aa)
	NECAME_11518	Low-density lipoprotein receptor repeat class B. (119 aa)
	NECAME_18099	NHL repeat protein. (297 aa)
	NECAME_09131	Low-density lipoprotein receptor domain class A. (564 aa)
	NECAME_08552	Low-density lipoprotein receptor repeat class B. (631 aa)
	NECAME_08107	NHL repeat protein. (406 aa)
	NECAME_07426	Low-density lipoprotein receptor domain class A. (912 aa)
	NECAME_01870	NHL repeat protein. (329 aa)
	NECAME_06614	Uncharacterized protein. (335 aa)
	NECAME_06561	EGF-like domain protein. (1102 aa)
	NECAME_01620	NHL repeat protein. (580 aa)

Your Current Organism:

Necator americanus

NCBI taxonomy Id: 51031
Other names: N. americanus

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NECAME_03451	NECAME_03452	W2T4L5	W2T3D6	Uncharacterized protein.	Uncharacterized protein.	0.681
NECAME_03452	NECAME_03451	W2T3D6	W2T4L5	Uncharacterized protein.	Uncharacterized protein.	0.681
NECAME_07426	NECAME_11518	W2TMN8	W2T664	Low-density lipoprotein receptor domain class A.	Low-density lipoprotein receptor repeat class B.	0.402
NECAME_11513	NECAME_11515	W2T657	W2T425	EGF-like domain-containing protein.	Uncharacterized protein.	0.595
NECAME_11513	NECAME_11517	W2T657	W2T3S5	EGF-like domain-containing protein.	Low-density lipoprotein receptor repeat class B.	0.747
NECAME_11513	NECAME_11518	W2T657	W2T664	EGF-like domain-containing protein.	Low-density lipoprotein receptor repeat class B.	0.798
NECAME_11513	NECAME_11520	W2T657	W2T431	EGF-like domain-containing protein.	Uncharacterized protein.	0.534
NECAME_11513	NECAME_18648	W2T657	W2STP0	EGF-like domain-containing protein.	Uncharacterized protein.	0.616
NECAME_11515	NECAME_11513	W2T425	W2T657	Uncharacterized protein.	EGF-like domain-containing protein.	0.595
NECAME_11515	NECAME_11517	W2T425	W2T3S5	Uncharacterized protein.	Low-density lipoprotein receptor repeat class B.	0.650
NECAME_11515	NECAME_11518	W2T425	W2T664	Uncharacterized protein.	Low-density lipoprotein receptor repeat class B.	0.716
NECAME_11517	NECAME_11513	W2T3S5	W2T657	Low-density lipoprotein receptor repeat class B.	EGF-like domain-containing protein.	0.747
NECAME_11517	NECAME_11515	W2T3S5	W2T425	Low-density lipoprotein receptor repeat class B.	Uncharacterized protein.	0.650
NECAME_11517	NECAME_11518	W2T3S5	W2T664	Low-density lipoprotein receptor repeat class B.	Low-density lipoprotein receptor repeat class B.	0.926
NECAME_11517	NECAME_11519	W2T3S5	W2T6N8	Low-density lipoprotein receptor repeat class B.	Low-density lipoprotein receptor domain class A.	0.571
NECAME_11517	NECAME_18648	W2T3S5	W2STP0	Low-density lipoprotein receptor repeat class B.	Uncharacterized protein.	0.650
NECAME_11518	NECAME_07426	W2T664	W2TMN8	Low-density lipoprotein receptor repeat class B.	Low-density lipoprotein receptor domain class A.	0.402
NECAME_11518	NECAME_11513	W2T664	W2T657	Low-density lipoprotein receptor repeat class B.	EGF-like domain-containing protein.	0.798
NECAME_11518	NECAME_11515	W2T664	W2T425	Low-density lipoprotein receptor repeat class B.	Uncharacterized protein.	0.716
NECAME_11518	NECAME_11517	W2T664	W2T3S5	Low-density lipoprotein receptor repeat class B.	Low-density lipoprotein receptor repeat class B.	0.926