STRINGSTRING
AO090206000030 AO090206000030 AO090010000727 AO090010000727 AO090010000525 AO090010000525 uba4 uba4 AO090010000312 AO090010000312 AO090010000266 AO090010000266 AO090010000236 AO090010000236 AO090103000448 AO090103000448 AO090103000447 AO090103000447 AO090103000151 AO090103000151 AO090103000098 AO090103000098 AO090103000010 AO090103000010 AO090011000914 AO090011000914 AO090011000670 AO090011000670 AO090011000033 AO090011000033 AO090138000099 AO090138000099 AO090038000258 AO090038000258 AO090038000235 AO090038000235 AO090020000619 AO090020000619 AO090020000509 AO090020000509 AO090020000504 AO090020000504 AO090020000339 AO090020000339 AO090020000234 AO090020000234 AO090020000180 AO090020000180 cnxH cnxH AO090020000116 AO090020000116 AO090020000099 AO090020000099 AO090113000124 AO090113000124 dre2 dre2 AO090113000102 AO090113000102 caf17 caf17 AO090120000294 AO090120000294 AO090120000273 AO090120000273 AO090120000112 AO090120000112 AO090120000084 AO090120000084 AO090120000060 AO090120000060 AO090120000059 AO090120000059 AO090120000027 AO090120000027 AO090124000013 AO090124000013 AO090124000001 AO090124000001 AO090701000682 AO090701000682 TAH18 TAH18 pbn1 pbn1 urm1 urm1 AO090166000064 AO090166000064 AO090166000063 AO090166000063 AO090102000595 AO090102000595 cfd1 cfd1 AO090102000564 AO090102000564 AO090102000379 AO090102000379 AO090102000297 AO090102000297 AO090102000213 AO090102000213 AO090102000137 AO090102000137 AO090102000110 AO090102000110 AO090012000998 AO090012000998 AO090012000973 AO090012000973 AO090012000676 AO090012000676 AO090012000604 AO090012000604 AO090012000414 AO090012000414 AO090012000275 AO090012000275 AO090012000265 AO090012000265 nbp35 nbp35 AO090012000205 AO090012000205 AO090026000708 AO090026000708 AO090026000661 AO090026000661 AO090026000421 AO090026000421 AO090026000356 AO090026000356 AO090026000291 AO090026000291 AO090026000065 AO090026000065 AO090023001007 AO090023001007 AO090023001002 AO090023001002 AO090023000909 AO090023000909 AO090023000863 AO090023000863 AO090023000725 AO090023000725 hxB hxB AO090023000552 AO090023000552 cprA cprA AO090023000415 AO090023000415 AO090023000378 AO090023000378 AO090023000377 AO090023000377 AO090023000319 AO090023000319 AO090023000141 AO090023000141 AO090023000140 AO090023000140 AO090003001488 AO090003001488 AO090003001279 AO090003001279 AO090003001232 AO090003001232 AO090003001160 AO090003001160 AO090003001146 AO090003001146 AO090003001143 AO090003001143 AO090003001062 AO090003001062 nar1 nar1 AO090003000898 AO090003000898 AO090003000803 AO090003000803 atm1 atm1 AO090003000401 AO090003000401 AO090003000251 AO090003000251 AO090003000180 AO090003000180 AO090003000107 AO090003000107 AO090001000667 AO090001000667 AO090001000538 AO090001000538 AO090001000537 AO090001000537 AO090001000500 AO090001000500 AO090001000231 AO090001000231 AO090001000110 AO090001000110 aclT aclT aclQ aclQ AO090005001652 AO090005001652 cia1 cia1 AO090005001625 AO090005001625 AO090005001600 AO090005001600 AO090005001092 AO090005001092 AO090005001065 AO090005001065 AO090005000812 AO090005000812 AO090005000739 AO090005000739 AO090005000612 AO090005000612 AO090005000611 AO090005000611 AO090005000430 AO090005000430 AO090005000241 AO090005000241 AO090009000473 AO090009000473 AO090009000289 AO090009000289 AO090009000151 AO090009000151 AO090009000149 AO090009000149 sodC sodC sodB sodB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AO090206000030Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (324 aa)
AO090010000727Uncharacterized protein. (641 aa)
AO090010000525Uncharacterized protein. (518 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (463 aa)
AO090010000312Uncharacterized protein; Belongs to the BolA/IbaG family. (107 aa)
AO090010000266Uncharacterized protein. (145 aa)
AO090010000236Uncharacterized protein. (255 aa)
AO090103000448Aminotran_5 domain-containing protein. (427 aa)
AO090103000447Uncharacterized protein. (531 aa)
AO090103000151Uncharacterized protein. (333 aa)
AO090103000098MOSC domain-containing protein. (221 aa)
AO090103000010FeS_assembly_P domain-containing protein. (203 aa)
AO090011000914MOSC domain-containing protein. (419 aa)
AO090011000670Sod_Cu domain-containing protein. (142 aa)
AO090011000033Uncharacterized protein. (184 aa)
AO090138000099Lactamase_B domain-containing protein. (296 aa)
AO090038000258Sod_Cu domain-containing protein. (128 aa)
AO090038000235Zn(2)-C6 fungal-type domain-containing protein. (465 aa)
AO090020000619Aminotran_5 domain-containing protein. (512 aa)
AO090020000509APH domain-containing protein. (336 aa)
AO090020000504Thioredoxin; Belongs to the thioredoxin family. (107 aa)
AO090020000339Uncharacterized protein; Belongs to the precorrin methyltransferase family. (558 aa)
AO090020000234Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (703 aa)
AO090020000180Thioredoxin domain-containing protein. (322 aa)
cnxHMolybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. (179 aa)
AO090020000116SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (321 aa)
AO090020000099Uncharacterized protein. (908 aa)
AO090113000124Uncharacterized protein. (261 aa)
dre2Fe-S cluster assembly protein dre2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35. Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18. Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (313 aa)
AO090113000102Uncharacterized protein. (119 aa)
caf17Putative transferase caf17, mitochondrial. (447 aa)
AO090120000294Uncharacterized protein. (342 aa)
AO090120000273PMSR domain-containing protein. (175 aa)
AO090120000112Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (168 aa)
AO090120000084Aminotran_5 domain-containing protein. (400 aa)
AO090120000060Uncharacterized protein. (324 aa)
AO090120000059Uncharacterized protein. (178 aa)
AO090120000027Arrestin_N domain-containing protein. (427 aa)
AO090124000013Uncharacterized protein. (230 aa)
AO090124000001ATP-grasp domain-containing protein. (625 aa)
AO090701000682Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (424 aa)
TAH18NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (643 aa)
pbn1Protein pbn1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity). (543 aa)
urm1Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (120 aa)
AO090166000064Uncharacterized protein. (854 aa)
AO090166000063Uncharacterized protein. (1271 aa)
AO0901020005952Fe-2S ferredoxin-type domain-containing protein. (210 aa)
cfd1Cytosolic Fe-S cluster assembly factor cfd1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (315 aa)
AO090102000564Pyr_redox_2 domain-containing protein. (384 aa)
AO090102000379Thioredoxin domain-containing protein. (105 aa)
AO090102000297Thioredoxin domain-containing protein. (107 aa)
AO090102000213Uncharacterized protein. (534 aa)
AO090102000137Uncharacterized protein. (259 aa)
AO090102000110Uncharacterized protein. (401 aa)
AO090012000998Uncharacterized protein. (437 aa)
AO090012000973Uncharacterized protein. (174 aa)
AO090012000676Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (166 aa)
AO090012000604Uncharacterized protein. (272 aa)
AO090012000414Uncharacterized protein. (297 aa)
AO090012000275Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (711 aa)
AO090012000265Uncharacterized protein. (845 aa)
nbp35Cytosolic Fe-S cluster assembly factor nbp35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (325 aa)
AO090012000205Uncharacterized protein. (330 aa)
AO090026000708Thioredoxin; Belongs to the thioredoxin family. (110 aa)
AO090026000661Uncharacterized protein. (929 aa)
AO090026000421Uncharacterized protein. (224 aa)
AO090026000356NADPH:adrenodoxin oxidoreductase, mitochondrial. (537 aa)
AO090026000291Aminotran_5 domain-containing protein. (461 aa)
AO090026000065Thioredoxin domain-containing protein. (118 aa)
AO090023001007Thioredoxin domain-containing protein. (207 aa)
AO090023001002Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (151 aa)
AO090023000909NifU_N domain-containing protein. (190 aa)
AO090023000863Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (290 aa)
AO090023000725Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (525 aa)
hxBMolybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (822 aa)
AO090023000552Aminotran_5 domain-containing protein. (438 aa)
cprANADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the N-terminal section; belongs to the flavodoxin family. (695 aa)
AO090023000415FGE-sulfatase domain-containing protein. (510 aa)
AO090023000378Ldi domain-containing protein. (278 aa)
AO090023000377Ldi domain-containing protein. (221 aa)
AO090023000319J domain-containing protein. (272 aa)
AO090023000141Lactamase_B domain-containing protein. (399 aa)
AO090023000140Pyr_redox_2 domain-containing protein. (447 aa)
AO090003001488Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (450 aa)
AO090003001279ATP-grasp domain-containing protein. (680 aa)
AO090003001232Uncharacterized protein. (789 aa)
AO090003001160Uncharacterized protein. (133 aa)
AO090003001146Fe-S_biosyn domain-containing protein. (237 aa)
AO090003001143Amino_oxidase domain-containing protein. (389 aa)
AO090003001062Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (230 aa)
nar1Cytosolic Fe-S cluster assembly factor nar1; Component of the cytosolic Fe/S protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity). (607 aa)
AO090003000898Uncharacterized protein. (176 aa)
AO090003000803Uroporphyrinogen_deCOase domain-containing protein. (378 aa)
atm1Iron-sulfur clusters transporter atm1, mitochondrial; Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating the ATP-dependent export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins. Hydrolyzes ATP. Binds glutathione and may function by transporting a glutathione-conjugated iron-sulfur compound (By similarity). (720 aa)
AO090003000401HEM4 domain-containing protein. (309 aa)
AO090003000251Ldi domain-containing protein. (559 aa)
AO090003000180Uncharacterized protein. (503 aa)
AO090003000107MOSC domain-containing protein. (353 aa)
AO090001000667Exonuclease domain-containing protein. (314 aa)
AO090001000538Uncharacterized protein. (139 aa)
AO090001000537Uncharacterized protein. (187 aa)
AO090001000500Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (597 aa)
AO090001000231ATP-grasp domain-containing protein. (695 aa)
AO090001000110Thioredoxin; Belongs to the thioredoxin family. (108 aa)
aclTThioredoxin reductase aclT; Thioredoxin reductase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells. The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues. One Phe residue is tailored into chlorotyrosine by hydroxylation and chlo [...] (334 aa)
aclQABC transporter aclQ; ABC transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells ; Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. (804 aa)
AO090005001652Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (375 aa)
cia1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (438 aa)
AO090005001625Yae1_N domain-containing protein. (193 aa)
AO090005001600Glutaredoxin domain-containing protein. (163 aa)
AO090005001092Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (472 aa)
AO090005001065Thioredoxin; Belongs to the thioredoxin family. (109 aa)
AO090005000812Flavodoxin-like domain-containing protein. (203 aa)
AO090005000739Glutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
AO090005000612MMS19_N domain-containing protein. (154 aa)
AO090005000611Uncharacterized protein. (901 aa)
AO090005000430Uncharacterized protein. (235 aa)
AO090005000241Thioredoxin domain-containing protein. (104 aa)
AO090009000473Glutaredoxin domain-containing protein. (102 aa)
AO090009000289Thioredoxin reductase. (353 aa)
AO090009000151Uncharacterized protein; Belongs to the BolA/IbaG family. (191 aa)
AO090009000149Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (182 aa)
sodCSuperoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
sodBSuperoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. (210 aa)
Your Current Organism:
Aspergillus oryzae
NCBI taxonomy Id: 510516
Other names: A. oryzae RIB40, Aspergillus oryzae RIB40
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