23 items (Aspergillus oryzae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fes1	Hsp70 nucleotide exchange factor fes1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (216 aa)
	AO090206000115	Uncharacterized protein. (558 aa)
	AO090206000025	AZUL domain-containing protein. (798 aa)
	AO090011000515	Uncharacterized protein. (1487 aa)
	AO090120000293	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (933 aa)
	AO090701000709	ANK_REP_REGION domain-containing protein. (640 aa)
	AO090102000107	Uncharacterized protein; Belongs to the AAA ATPase family. (821 aa)
	AO090026000545	U-box domain-containing protein. (267 aa)
	AO090026000514	AMP-binding domain-containing protein. (623 aa)
	PIM1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1114 aa)
	AO090026000471	Uncharacterized protein. (537 aa)
	sts1	Tethering factor for nuclear proteasome sts1; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity). (312 aa)
	AO090023000816	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (456 aa)
	AO090003001258	Peptidase_M48 domain-containing protein. (167 aa)
	AO090003001068	AAA domain-containing protein. (719 aa)
	AO090005001575	Uncharacterized protein. (715 aa)
	AO090005001444	ATP-dependent Clp protease proteolytic subunit. (267 aa)
	AO090009000265	Uncharacterized protein. (450 aa)
	AO090009000475	Uncharacterized protein. (299 aa)
	AO090005001099	Ubiquitin carboxyl-terminal hydrolase. (311 aa)
	AO090005000853	Uncharacterized protein. (369 aa)
	npl4	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa)
	AO090009000582	Uncharacterized protein. (632 aa)

Your Current Organism:

Aspergillus oryzae

NCBI taxonomy Id: 510516
Other names: A. oryzae RIB40, Aspergillus oryzae RIB40

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AO090003001068	AO090003001258	Q2UJU6	Q2UJD8	AAA domain-containing protein.	Peptidase_M48 domain-containing protein.	0.703
AO090003001068	AO090005001444	Q2UJU6	Q2UPZ9	AAA domain-containing protein.	ATP-dependent Clp protease proteolytic subunit.	0.645
AO090003001068	AO090023000816	Q2UJU6	Q2UGJ7	AAA domain-containing protein.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.409
AO090003001068	AO090026000471	Q2UJU6	Q2UEV0	AAA domain-containing protein.	Uncharacterized protein.	0.424
AO090003001068	AO090120000293	Q2UJU6	Q2U6C7	AAA domain-containing protein.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.601
AO090003001068	PIM1	Q2UJU6	Q2UEU9	AAA domain-containing protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.633
AO090003001258	AO090003001068	Q2UJD8	Q2UJU6	Peptidase_M48 domain-containing protein.	AAA domain-containing protein.	0.703
AO090003001258	AO090005001444	Q2UJD8	Q2UPZ9	Peptidase_M48 domain-containing protein.	ATP-dependent Clp protease proteolytic subunit.	0.434
AO090003001258	AO090023000816	Q2UJD8	Q2UGJ7	Peptidase_M48 domain-containing protein.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.583
AO090003001258	AO090120000293	Q2UJD8	Q2U6C7	Peptidase_M48 domain-containing protein.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.417
AO090003001258	PIM1	Q2UJD8	Q2UEU9	Peptidase_M48 domain-containing protein.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.418
AO090005000853	AO090102000107	Q2URF2	Q2UB52	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.997
AO090005000853	AO090701000709	Q2URF2	Q2U7T4	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.588
AO090005000853	npl4	Q2URF2	Q2URI8	Uncharacterized protein.	Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family.	0.999
AO090005001444	AO090003001068	Q2UPZ9	Q2UJU6	ATP-dependent Clp protease proteolytic subunit.	AAA domain-containing protein.	0.645
AO090005001444	AO090003001258	Q2UPZ9	Q2UJD8	ATP-dependent Clp protease proteolytic subunit.	Peptidase_M48 domain-containing protein.	0.434
AO090005001444	AO090023000816	Q2UPZ9	Q2UGJ7	ATP-dependent Clp protease proteolytic subunit.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.434
AO090005001444	AO090120000293	Q2UPZ9	Q2U6C7	ATP-dependent Clp protease proteolytic subunit.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.704
AO090005001444	PIM1	Q2UPZ9	Q2UEU9	ATP-dependent Clp protease proteolytic subunit.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.704
AO090009000475	AO090026000545	Q2UU36	Q2UEN9	Uncharacterized protein.	U-box domain-containing protein.	0.690