STRINGSTRING
AO090038000310 AO090038000310 AO090038000045 AO090038000045 AO090020000482 AO090020000482 AO090102000454 AO090102000454 AO090102000348 AO090102000348 tim22 tim22 AO090102000208 AO090102000208 AO090102000151 AO090102000151 sec11 sec11 AO090012000778 AO090012000778 AO090012000548 AO090012000548 AO090012000436 AO090012000436 AO090012000159 AO090012000159 AO090673000002 AO090673000002 AO090026000703 AO090026000703 AO090026000550 AO090026000550 AO090026000361 AO090026000361 AO090026000264 AO090026000264 AO090023000496 AO090023000496 AO090023000476 AO090023000476 AO090023000133 AO090023000133 AO090020000399 AO090020000399 AO090020000312 AO090020000312 AO090020000103 AO090020000103 AO090113000006 AO090113000006 mdmB mdmB AO090120000410 AO090120000410 AO090120000351 AO090120000351 AO090120000293 AO090120000293 AO090120000245 AO090120000245 AO090120000129 AO090120000129 AO090120000098 AO090120000098 AO090124000073 AO090124000073 AO090701000781 AO090701000781 atg3 atg3 AO090701000730 AO090701000730 AO090701000703 AO090701000703 AO090701000413 AO090701000413 AO090701000381 AO090701000381 AO090701000291 AO090701000291 AO090701000163 AO090701000163 mmm1 mmm1 AO090701000032 AO090701000032 AO090701000026 AO090701000026 AO090166000035 AO090166000035 AO090102000593 AO090102000593 AO090102000572 AO090102000572 AO090102000523 AO090102000523 AO090009000027 AO090009000027 AO090009000100 AO090009000100 AO090009000415 AO090009000415 AO090009000431 AO090009000431 AO090009000627 AO090009000627 AO090005000001 AO090005000001 AO090005000100 AO090005000100 AO090005000111 AO090005000111 AO090005000132 AO090005000132 AO090005000133 AO090005000133 AO090003000258 AO090003000258 AO090003000257 AO090003000257 AO090003000215 AO090003000215 AO090003000195 AO090003000195 AO090003000102 AO090003000102 oct1 oct1 AO090001000378 AO090001000378 AO090001000377 AO090001000377 AO090001000107 AO090001000107 mdm12 mdm12 AO090005001628 AO090005001628 AO090005001413 AO090005001413 AO090005001395 AO090005001395 AO090005001355 AO090005001355 mia40 mia40 AO090005000568 AO090005000568 AO090005000623 AO090005000623 AO090005000629 AO090005000629 AO090005000730 AO090005000730 AO090005000882 AO090005000882 AO090005001175 AO090005001175 AO090003001323 AO090003001323 AO090003001205 AO090003001205 AO090003001064 AO090003001064 AO090003001000 AO090003001000 AO090003000999 AO090003000999 AO090005001238 AO090005001238 AO090003000956 AO090003000956 AO090003000853 AO090003000853 get3 get3 AO090003000675 AO090003000675 AO090003000663 AO090003000663 AO090003000644 AO090003000644 AO090003000619 AO090003000619 AO090003000555 AO090003000555 AO090003000539 AO090003000539 mon1 mon1 AO090206000081 AO090206000081 AO090206000027 AO090206000027 vps10 vps10 AO090010000271 AO090010000271 AO090010000203 AO090010000203 AO090103000044 AO090103000044 AO090011000933 AO090011000933 AO090011000764 AO090011000764 AO090011000653 AO090011000653 AO090011000621 AO090011000621 AO090011000534 AO090011000534 AO090011000469 AO090011000469 AO090011000318 AO090011000318 AO090011000339 AO090011000339 AO090011000166 AO090011000166 AO090138000126 AO090138000126 AO090038000562 AO090038000562 AO090038000455 AO090038000455 AO090038000454 AO090038000454 AO090038000311 AO090038000311
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AO090038000310Uncharacterized protein. (144 aa)
AO090038000045Uncharacterized protein. (325 aa)
AO090020000482WSC domain-containing protein. (352 aa)
AO090102000454V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (159 aa)
AO090102000348GED domain-containing protein. (383 aa)
tim22Mitochondrial import inner membrane translocase subunit tim22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (184 aa)
AO090102000208Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (530 aa)
AO090102000151RING-type domain-containing protein. (488 aa)
sec11Signal peptidase complex catalytic subunit sec11; Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity). (191 aa)
AO090012000778Peptidase_S24 domain-containing protein. (210 aa)
AO090012000548Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
AO090012000436Uncharacterized protein; Belongs to the peptidase M16 family. (479 aa)
AO090012000159Uncharacterized protein. (193 aa)
AO090673000002AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (956 aa)
AO090026000703Adaptin_N domain-containing protein. (830 aa)
AO090026000550Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (182 aa)
AO090026000361Uncharacterized protein. (294 aa)
AO090026000264GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (247 aa)
AO090023000496Uncharacterized protein. (1612 aa)
AO090023000476Uncharacterized protein. (170 aa)
AO090023000133Uncharacterized protein. (214 aa)
AO090020000399Uncharacterized protein. (211 aa)
AO090020000312Uncharacterized protein. (501 aa)
AO090020000103Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (612 aa)
AO090113000006Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (829 aa)
mdmBMitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (431 aa)
AO090120000410Peptidase_S24 domain-containing protein. (178 aa)
AO090120000351SRP9-21 domain-containing protein. (149 aa)
AO090120000293Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (933 aa)
AO090120000245Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (523 aa)
AO090120000129UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
AO090120000098Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (507 aa)
AO090124000073Uncharacterized protein. (209 aa)
AO090701000781Uncharacterized protein. (632 aa)
atg3Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of [...] (356 aa)
AO090701000730Plug_translocon domain-containing protein. (478 aa)
AO090701000703Erf4 domain-containing protein. (249 aa)
AO090701000413Uncharacterized protein. (127 aa)
AO090701000381UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa)
AO090701000291TPR_REGION domain-containing protein. (214 aa)
AO090701000163SRP54 domain-containing protein. (607 aa)
mmm1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (494 aa)
AO090701000032Uncharacterized protein. (346 aa)
AO090701000026Uncharacterized protein. (355 aa)
AO090166000035Uncharacterized protein. (182 aa)
AO090102000593Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (527 aa)
AO090102000572Uncharacterized protein. (124 aa)
AO090102000523Signal peptidase subunit 3. (245 aa)
AO090009000027Uncharacterized protein. (149 aa)
AO090009000100Uncharacterized protein. (695 aa)
AO090009000415Pex2_Pex12 domain-containing protein. (516 aa)
AO090009000431Uncharacterized protein. (186 aa)
AO090009000627Uncharacterized protein. (531 aa)
AO090005000001Uncharacterized protein. (295 aa)
AO090005000100Uncharacterized protein. (134 aa)
AO090005000111RING-type domain-containing protein. (373 aa)
AO090005000132Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (329 aa)
AO090005000133Uncharacterized protein. (602 aa)
AO090003000258Uncharacterized protein. (191 aa)
AO090003000257Uncharacterized protein; Belongs to the heat shock protein 70 family. (672 aa)
AO090003000215Uncharacterized protein. (124 aa)
AO090003000195Uncharacterized protein. (202 aa)
AO090003000102DNL-type domain-containing protein. (194 aa)
oct1Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity). (800 aa)
AO090001000378Uncharacterized protein. (153 aa)
AO090001000377Uncharacterized protein; Belongs to the peptidase M16 family. (583 aa)
AO090001000107Uncharacterized protein. (114 aa)
mdm12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (432 aa)
AO090005001628Uncharacterized protein. (441 aa)
AO090005001413Uncharacterized protein. (122 aa)
AO090005001395MPN domain-containing protein. (461 aa)
AO090005001355Uncharacterized protein. (113 aa)
mia40Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (187 aa)
AO090005000568Uncharacterized protein. (167 aa)
AO090005000623TPR_REGION domain-containing protein. (660 aa)
AO090005000629SH3 domain-containing protein. (430 aa)
AO090005000730V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (102 aa)
AO090005000882Uncharacterized protein. (609 aa)
AO090005001175WD_REPEATS_REGION domain-containing protein. (355 aa)
AO090003001323Uncharacterized protein. (187 aa)
AO090003001205Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (648 aa)
AO090003001064Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3170 aa)
AO090003001000Uncharacterized protein. (1711 aa)
AO090003000999UBIQUITIN_CONJUGAT_2 domain-containing protein. (139 aa)
AO090005001238J domain-containing protein. (696 aa)
AO090003000956Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (613 aa)
AO090003000853Uncharacterized protein. (146 aa)
get3ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (339 aa)
AO090003000675Uncharacterized protein. (1305 aa)
AO090003000663Uncharacterized protein. (785 aa)
AO090003000644Uncharacterized protein. (383 aa)
AO090003000619Uncharacterized protein. (264 aa)
AO090003000555Pex14_N domain-containing protein. (370 aa)
AO090003000539Uncharacterized protein. (492 aa)
mon1Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (628 aa)
AO090206000081GLUE N-terminal domain-containing protein. (555 aa)
AO090206000027Bac_surface_Ag domain-containing protein. (516 aa)
vps10Vacuolar protein sorting/targeting protein 10; Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A. Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment; Belongs to the VPS10-related sortilin family. (1488 aa)
AO090010000271Uncharacterized protein. (722 aa)
AO090010000203J domain-containing protein. (484 aa)
AO090103000044Uncharacterized protein. (270 aa)
AO090011000933Uncharacterized protein. (320 aa)
AO090011000764Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (588 aa)
AO090011000653Uncharacterized protein. (236 aa)
AO090011000621Uncharacterized protein. (1207 aa)
AO090011000534Uncharacterized protein. (108 aa)
AO090011000469Uncharacterized protein. (127 aa)
AO090011000318AAA domain-containing protein; Belongs to the AAA ATPase family. (394 aa)
AO090011000339Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (262 aa)
AO090011000166Uncharacterized protein. (455 aa)
AO090138000126Uncharacterized protein. (725 aa)
AO090038000562Uncharacterized protein. (579 aa)
AO090038000455Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (518 aa)
AO090038000454TPR_REGION domain-containing protein. (357 aa)
AO090038000311Uncharacterized protein. (103 aa)
Your Current Organism:
Aspergillus oryzae
NCBI taxonomy Id: 510516
Other names: A. oryzae RIB40, Aspergillus oryzae RIB40
Server load: low (16%) [HD]