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| | MEF2 | Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (843 aa) |
| | AO090701000413 | Uncharacterized protein. (127 aa) |
| | AO090701000557 | Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (400 aa) |
| | AO090701000700 | Uncharacterized protein. (183 aa) |
| | atg3 | Autophagy-related protein 3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8. The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of [...] (356 aa) |
| | AO090701000781 | Uncharacterized protein. (632 aa) |
| | AO090120000203 | Uncharacterized protein. (377 aa) |
| | AO090120000245 | Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (523 aa) |
| | AO090120000247 | MPN domain-containing protein. (411 aa) |
| | AO090120000264 | Uncharacterized protein; Belongs to the BI1 family. (337 aa) |
| | AO090120000281 | Uncharacterized protein. (233 aa) |
| | AO090120000387 | Uncharacterized protein. (394 aa) |
| | AO090120000390 | POLAc domain-containing protein. (1017 aa) |
| | AO090120000410 | Peptidase_S24 domain-containing protein. (178 aa) |
| | mdv1 | Mitochondrial division protein 1; Involved in mitochondrial fission. Acts as an adapter protein required to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity); Belongs to the WD repeat MDV1/CAF4 family. (650 aa) |
| | AO090120000478 | Uncharacterized protein. (345 aa) |
| | AO090120000479 | PPM-type phosphatase domain-containing protein. (570 aa) |
| | AO090120000482 | ATP-dependent DNA helicase; Belongs to the helicase family. (366 aa) |
| | AO090120000484 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (932 aa) |
| | mdmB | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (431 aa) |
| | AO090020000114 | Uncharacterized protein. (186 aa) |
| | AO090020000116 | SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (321 aa) |
| | AO090020000180 | Thioredoxin domain-containing protein. (322 aa) |
| | AO090020000299 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (414 aa) |
| | AO090020000312 | Uncharacterized protein. (501 aa) |
| | sar1 | Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa) |
| | AO090009000100 | Uncharacterized protein. (695 aa) |
| | atg9 | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machinerie [...] (951 aa) |
| | AO090012000548 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa) |
| | AO090012000533 | Prohibitin. (280 aa) |
| | AO090012000436 | Uncharacterized protein; Belongs to the peptidase M16 family. (479 aa) |
| | AO090026000803 | Uncharacterized protein; Belongs to the AAA ATPase family. (570 aa) |
| | AO090026000799 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (396 aa) |
| | cbp4 | Assembly factor cbp4; Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity). Belongs to the CBP4 family. (116 aa) |
| | PIM1 | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1114 aa) |
| | AO090026000471 | Uncharacterized protein. (537 aa) |
| | AO090026000393 | Uncharacterized protein. (150 aa) |
| | fis1 | Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity). (153 aa) |
| | AO090026000264 | GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (247 aa) |
| | AO090026000165 | Tafazzin family protein; Belongs to the taffazin family. (380 aa) |
| | AO090026000164 | Uncharacterized protein. (581 aa) |
| | atg17 | Autophagy-related protein 17; Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize pre-autophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy (By similarity); Belongs to the ATG17 family. (550 aa) |
| | AO090672000005 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (228 aa) |
| | AO090023001006 | PRELI/MSF1 domain-containing protein. (190 aa) |
| | AO090023000998 | Uncharacterized protein. (184 aa) |
| | AO090023000910 | ABC1 domain-containing protein. (622 aa) |
| | AO090023000844 | SAP domain-containing protein. (366 aa) |
| | AO090023000766 | MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (607 aa) |
| | rcf1 | Respiratory supercomplex factor 1, mitochondrial; Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes. (176 aa) |
| | atg1 | Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (934 aa) |
| | AO090023000580 | DAO domain-containing protein. (406 aa) |
| | AO090023000526 | Uncharacterized protein. (609 aa) |
| | AO090023000476 | Uncharacterized protein. (170 aa) |
| | AO090023000378 | Ldi domain-containing protein. (278 aa) |
| | AO090023000377 | Ldi domain-containing protein. (221 aa) |
| | AO090023000133 | Uncharacterized protein. (214 aa) |
| | mdm34 | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (566 aa) |
| | AO090003001068 | AAA domain-containing protein. (719 aa) |
| | AO090003001064 | Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3170 aa) |
| | AO090003000902 | Uncharacterized protein. (109 aa) |
| | AO090003000843 | Uncharacterized protein. (721 aa) |
| | AO090003000814 | N-acetyltransferase domain-containing protein. (173 aa) |
| | AO090003000789 | TYR_PHOSPHATASE_2 domain-containing protein. (609 aa) |
| | AO090003000718 | ATG11 domain-containing protein. (1201 aa) |
| | AO090003000668 | DNA ligase. (827 aa) |
| | AO090003000664 | Uncharacterized protein. (579 aa) |
| | clu1 | Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. (1249 aa) |
| | AO090003000616 | Methyltransf_11 domain-containing protein. (353 aa) |
| | AO090003000615 | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa) |
| | AO090003000415 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (779 aa) |
| | AO090003000407 | Altered inheritance of mitochondria protein 24, mitochondrial. (185 aa) |
| | AO090003000406 | Altered inheritance of mitochondria protein 24, mitochondrial. (175 aa) |
| | AO090003000251 | Ldi domain-containing protein. (559 aa) |
| | AO090003000235 | Uncharacterized protein. (726 aa) |
| | AO090009000292 | PX domain-containing protein. (496 aa) |
| | AO090003000215 | Uncharacterized protein. (124 aa) |
| | gem1 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. (633 aa) |
| | AO090003000102 | DNL-type domain-containing protein. (194 aa) |
| | AO090003000029 | Uncharacterized protein. (135 aa) |
| | AO090003000012 | Uncharacterized protein. (586 aa) |
| | AO090001000744 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (719 aa) |
| | AO090001000614 | Uncharacterized protein. (331 aa) |
| | oct1 | Mitochondrial intermediate peptidase; Cleaves proteins, imported into the mitochondrion, to their mature size. While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity). (800 aa) |
| | AO090001000524 | MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (244 aa) |
| | AO090009000618 | Uncharacterized protein. (180 aa) |
| | AO090005000100 | Uncharacterized protein. (134 aa) |
| | AO090005000159 | Uncharacterized protein. (340 aa) |
| | mia40 | Mitochondrial intermembrane space import and assembly protein 40; Required for the import and folding of small cysteine- containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Forms a redox cycle with ERV1 that involves a disulfide relay system. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond [...] (187 aa) |
| | AO090005000418 | Uncharacterized protein. (662 aa) |
| | AO090005000456 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (456 aa) |
| | AO090005000695 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (962 aa) |
| | AO090005000882 | Uncharacterized protein. (609 aa) |
| | AO090020000399 | Uncharacterized protein. (211 aa) |
| | AO090020000489 | Uncharacterized protein. (117 aa) |
| | AO090020000632 | Uncharacterized protein; Belongs to the AAA ATPase family. (465 aa) |
| | AO090038000288 | Uncharacterized protein; Belongs to the ClpA/ClpB family. (811 aa) |
| | AO090038000377 | Uncharacterized protein. (369 aa) |
| | AO090038000431 | HMG box domain-containing protein. (321 aa) |
| | AO090038000455 | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (518 aa) |
| | AO090038000497 | AAA domain-containing protein. (784 aa) |
| | AO090038000562 | Uncharacterized protein. (579 aa) |
| | AO090038000603 | Uncharacterized protein. (232 aa) |
| | AO090038000615 | Uncharacterized protein. (154 aa) |
| | AO090038000623 | zf-Mss51 domain-containing protein. (551 aa) |
| | AO090038000625 | Uncharacterized protein. (225 aa) |
| | AO090138000126 | Uncharacterized protein. (725 aa) |
| | MZM1 | Mitochondrial zinc maintenance protein 1, mitochondrial; Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane. Modulates the mitochondrial matrix zinc pool (By similarity). (114 aa) |
| | AO090011000318 | AAA domain-containing protein; Belongs to the AAA ATPase family. (394 aa) |
| | AO090011000502 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (176 aa) |
| | AO090011000534 | Uncharacterized protein. (108 aa) |
| | AO090011000653 | Uncharacterized protein. (236 aa) |
| | AO090011000666 | Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (535 aa) |
| | AO090011000707 | Uncharacterized protein. (280 aa) |
| | AO090011000764 | Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (588 aa) |
| | AO090011000790 | Prohibitin. (310 aa) |
| | AO090011000939 | Uncharacterized protein. (189 aa) |
| | AO090103000199 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (172 aa) |
| | AO090103000283 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (533 aa) |
| | AO090010000271 | Uncharacterized protein. (722 aa) |
| | AO090010000459 | Uncharacterized protein. (635 aa) |
| | she9 | Sensitive to high expression protein 9 homolog, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed (By similarity). (328 aa) |
| | AO090010000713 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (350 aa) |
| | AO090010000776 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (799 aa) |
| | cox16 | Cytochrome c oxidase assembly protein cox16, mitochondrial; Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. May participate in merging the COX1 and COX2 assembly lines. Belongs to the COX16 family. (134 aa) |
| | AO090206000027 | Bac_surface_Ag domain-containing protein. (516 aa) |
| | AO090206000108 | Uncharacterized protein. (332 aa) |
| | AO090005001077 | Uncharacterized protein. (199 aa) |
| | dml1 | Protein dml1; Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance; Belongs to the misato family. (493 aa) |
| | mdm12 | Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (432 aa) |
| | AO090005001272 | Uncharacterized protein. (115 aa) |
| | AO090005001339 | Uncharacterized protein. (100 aa) |
| | AO090005001355 | Uncharacterized protein. (113 aa) |
| | AO090005001391 | Uncharacterized protein. (119 aa) |
| | AO090005001413 | Uncharacterized protein. (122 aa) |
| | AO090005001455 | Letm1 RBD domain-containing protein. (543 aa) |
| | AO090005001510 | Ig-like domain-containing protein. (431 aa) |
| | AO090001000304 | HIG1 domain-containing protein. (261 aa) |
| | AO090001000357 | Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (918 aa) |
| | AO090012000778 | Peptidase_S24 domain-containing protein. (210 aa) |
| | AO090012000830 | Uncharacterized protein; Belongs to the AAA ATPase family. (505 aa) |
| | AO090012000865 | PHB domain-containing protein. (436 aa) |
| | yme2 | Mitochondrial escape protein 2; Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape. Involved in the regulation of mtDNA nucleotide structure and number. May have a dispensable role in early maturation of pre-rRNA (By similarity); Belongs to the YME2 family. (864 aa) |
| | tim22 | Mitochondrial import inner membrane translocase subunit tim22; Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity). (184 aa) |
| | AO090102000339 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (469 aa) |
| | AO090102000505 | DUF3395 domain-containing protein. (342 aa) |
| | AO090102000572 | Uncharacterized protein. (124 aa) |
| | AO090102000573 | Uncharacterized protein. (467 aa) |
| | AO090102000596 | Uncharacterized protein. (509 aa) |
| | AO090166000035 | Uncharacterized protein. (182 aa) |
| | AO090701000026 | Uncharacterized protein. (355 aa) |
| | AO090001000377 | Uncharacterized protein; Belongs to the peptidase M16 family. (583 aa) |
| | AO090001000378 | Uncharacterized protein. (153 aa) |
| | AO090001000459 | Uncharacterized protein. (226 aa) |
| | AO090001000489 | Uncharacterized protein. (369 aa) |
| | AO090701000040 | FAD-binding FR-type domain-containing protein. (379 aa) |
| | AO090001000518 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1087 aa) |
| | AO090701000049 | Uncharacterized protein. (358 aa) |
| | mmm1 | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (494 aa) |
| | AO090701000120 | PUM-HD domain-containing protein. (860 aa) |
