(31 nodes) Histidine kinase/HSP90-like ATPase network (Alcaligenes faecalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALO39277.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
	ALO39354.1	C4-dicarboxylate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)
	ALO39483.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (507 aa)
	ALO39530.1	Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology. (699 aa)
	ALO39636.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
	ALO39675.1	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (988 aa)
	ALO39733.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (889 aa)
	ALO39856.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
	ALO39935.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (845 aa)
	ALO40516.1	Two-component sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
	ALO36867.1	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
	ALO36972.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
	ALO37017.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
	ALO37042.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	ALO37109.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
	parE	DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (653 aa)
	ALO37251.1	Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (1147 aa)
	ALO37255.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
	ALO40246.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa)
	ALO37547.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (930 aa)
	ALO37548.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1047 aa)
	ALO37795.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
	ALO37866.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
	ALO38073.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (656 aa)
	htpG	Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity. (634 aa)
	gyrB	DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (817 aa)
	ALO39031.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
	ALO40411.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (778 aa)
	ALO39095.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
	phoR	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
	ALO39255.1	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)

Your Current Organism:

Alcaligenes faecalis

NCBI taxonomy Id: 511
Other names: A. faecalis, ATCC 8750, Achromobacter sp. ATCC8750, Alcaligenes sp. BP11, CIP 55.84, CIP 60.80, DSM 30030, IAM 12369, IFO 13111, JCM 20522, JCM 20663, NBRC 13111, NCAIM B.01104, NCIMB 8156, NCTC 11953

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALO36867.1	ALO36972.1	UZ73_00510	UZ73_01060	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
ALO36867.1	ALO37017.1	UZ73_00510	UZ73_01305	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.741
ALO36867.1	ALO37042.1	UZ73_00510	UZ73_01455	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.898
ALO36867.1	ALO37109.1	UZ73_00510	UZ73_01850	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.799
ALO36867.1	ALO37251.1	UZ73_00510	UZ73_02595	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
ALO36867.1	ALO37255.1	UZ73_00510	UZ73_02615	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.809
ALO36867.1	ALO37547.1	UZ73_00510	UZ73_04290	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
ALO36867.1	ALO37548.1	UZ73_00510	UZ73_04295	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.706
ALO36867.1	ALO37795.1	UZ73_00510	UZ73_05675	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.760
ALO36867.1	ALO37866.1	UZ73_00510	UZ73_06110	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.712
ALO36867.1	ALO38073.1	UZ73_00510	UZ73_07265	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.692
ALO36867.1	ALO39031.1	UZ73_00510	UZ73_12620	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.842
ALO36867.1	ALO39095.1	UZ73_00510	UZ73_12995	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.741
ALO36867.1	ALO39255.1	UZ73_00510	UZ73_13875	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.461
ALO36867.1	ALO39277.1	UZ73_00510	UZ73_13990	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.758
ALO36867.1	ALO39354.1	UZ73_00510	UZ73_14420	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	C4-dicarboxylate transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
ALO36867.1	ALO39483.1	UZ73_00510	UZ73_15115	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.818
ALO36867.1	ALO39530.1	UZ73_00510	UZ73_15415	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Chemotaxis protein CheA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.823
ALO36867.1	ALO39636.1	UZ73_00510	UZ73_15995	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.716
ALO36867.1	ALO39675.1	UZ73_00510	UZ73_16205	PAS domain-containing sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Response regulator receiver protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999

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