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| | rsmI | Hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (226 aa) |
| | nusA | Transcription elongation protein NusA; Participates in both transcription termination and antitermination. (352 aa) |
| | rsmG-2 | Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (187 aa) |
| | mfd | Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1100 aa) |
| | CSE_13410 | Hypothetical protein. (252 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (399 aa) |
| | CSE_13520 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (174 aa) |
| | CSE_13560 | Hypothetical protein. (496 aa) |
| | CSE_13610 | Hypothetical protein. (312 aa) |
| | CSE_13930 | Hypothetical protein. (316 aa) |
| | CSE_14000 | Putative transposase for insertion sequence element. (544 aa) |
| | CSE_14600 | Hypothetical protein. (231 aa) |
| | CSE_14760 | Hypothetical protein. (73 aa) |
| | mnmE | tRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (446 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (117 aa) |
| | CSE_15070 | Hypothetical protein. (119 aa) |
| | CSE_15180 | Putative transposase for insertion sequence element. (472 aa) |
| | CSE_15270 | Hypothetical protein. (79 aa) |
| | CSE_15280 | Hypothetical protein. (81 aa) |
| | CSE_15370 | Hypothetical protein. (100 aa) |
| | CSE_15390 | Hypothetical protein. (1803 aa) |
| | CSE_15440 | Hypothetical protein. (471 aa) |
| | rgy | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1159 aa) |
| | uvrA | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | CSE_15740 | Putative transposase for insertion sequence element. (556 aa) |
| | CSE_15810 | Putative transposase for insertion sequence element. (544 aa) |
| | CSE_15820 | Putative transposase for insertion sequence element. (210 aa) |
| | CSE_02590 | Putative methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (266 aa) |
| | CSE_02730 | Putative CRISPR-associated protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (169 aa) |
| | cas1 | Putative CRISPR-associated protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (326 aa) |
| | cas2 | Putative CRISPR-associated protein; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (88 aa) |
| | CSE_03000 | Hypothetical protein. (241 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (708 aa) |
| | CSE_03210 | uracil-DNA glycosylase. (192 aa) |
| | dtd | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (154 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (438 aa) |
| | ssb | Single-stranded DNA-binding protein; Protein synonym:helix-destabilizing protein. (132 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (627 aa) |
| | CSE_03570 | Putative transposase for insertion sequence element. (556 aa) |
| | CSE_03720 | Putative DNA glycosylase. (289 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1048 aa) |
| | holB | Putative DNA polymerase III delta' subunit. (324 aa) |
| | mnmA | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (338 aa) |
| | CSE_03970 | DsrH family protein. (92 aa) |
| | CSE_03980 | Hypothetical protein. (119 aa) |
| | CSE_03990 | DrsE family protein. (117 aa) |
| | CSE_04010 | Hypothetical protein; Belongs to the sulfur carrier protein TusA family. (79 aa) |
| | rlmH | Ribosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (139 aa) |
| | xthA | Exodeoxyribonuclease III. (253 aa) |
| | ksgA | Protein synonym:16S rRNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (269 aa) |
| | argS | arginyl-tRNA synthetase; Protein synonym:arginine--tRNA ligase. (579 aa) |
| | ogt | methylated-DNA--protein-cysteine methyltransferase; Protein synonym:O-6-methylguanine-DNA alkyltransferase. (157 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (283 aa) |
| | CSE_04650 | Hypothetical protein. (62 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (860 aa) |
| | CSE_04720 | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (147 aa) |
| | CSE_04750 | Hypothetical protein. (99 aa) |
| | CSE_04850 | Putative CC-adding enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (360 aa) |
| | miaB | (dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (425 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Protein synonym:tryptophan--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (325 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa) |
| | CSE_05100 | Putative transposase for insertion sequence element. (472 aa) |
| | CSE_05240 | Putative transposase for insertion sequence element. (556 aa) |
| | CSE_05250 | RmuC family protein. (318 aa) |
| | CSE_05470 | MiaB-like tRNA modifying enzyme family protein. (414 aa) |
| | queH | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (208 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (246 aa) |
| | leuS | leucyl-tRNA synthetase; Protein synonym:leucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (819 aa) |
| | CSE_05920 | Hypothetical protein. (306 aa) |
| | trmD | tRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (250 aa) |
| | CSE_06080 | Hypothetical protein. (194 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (202 aa) |
| | CSE_06130 | Hypothetical protein; Belongs to the UPF0102 family. (112 aa) |
| | rnj | Putative ribonuclease J; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (554 aa) |
| | lexA | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response). (197 aa) |
| | CSE_06170 | Hypothetical protein. (245 aa) |
| | ligA | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (678 aa) |
| | CSE_06350 | Putative asparagine synthetase A. (293 aa) |
| | gyrA | DNA gyrase subunit A. (811 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (649 aa) |
| | rpoN | Putative RNA polymerase sigma-54 factor. (412 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (364 aa) |
| | CSE_07000 | Hypothetical protein. (213 aa) |
| | CSE_07010 | Putative DNA polymerase family X. (574 aa) |
| | uvrB | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (666 aa) |
| | rtcB | Hypothetical protein; Belongs to the RtcB family. (476 aa) |
| | nfo | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (287 aa) |
| | rlmN | Hypothetical protein; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (349 aa) |
| | rimO | Putative ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (429 aa) |
| | recA | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (338 aa) |
| | rny | 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (515 aa) |
| | uvrC | Putative UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (535 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (375 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (582 aa) |
| | hisS | histidyl-tRNA synthetase; Protein synonym:histidine--tRNA ligase. (417 aa) |
| | CSE_07470 | alanyl-tRNA synthetase related protein. (366 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (790 aa) |
| | CSE_07720 | Putative methyltransferase. (186 aa) |
| | nusB | N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (136 aa) |
| | recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (573 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (568 aa) |
| | CSE_08130 | Hypothetical protein. (370 aa) |
| | CSE_02580 | Hypothetical protein; Belongs to the TtcA family. (304 aa) |
| | CSE_08180 | Putative ATP-dependent helicase. (746 aa) |
| | ybeY | Putative metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (157 aa) |
| | psuG | Hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (300 aa) |
| | rpoD | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (392 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (574 aa) |
| | glyS | Protein synonym:glycine--tRNA ligase beta subunit. (694 aa) |
| | glyQ | Protein synonym:glycine--tRNA ligase alpha subunit. (287 aa) |
| | recO | Recombination protein O RecO family protein; Involved in DNA repair and RecF pathway recombination. (235 aa) |
| | dnaX | DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (531 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (202 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase/AP lyase; Bifunctional protein; Belongs to the FPG family. (272 aa) |
| | comEA | Putative competence protein ComEA. (195 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (303 aa) |
| | rimN | Putative ribosome maturation factor RimN; Belongs to the SUA5 family. (191 aa) |
| | CSE_08570 | Hypothetical protein. (133 aa) |
| | tdk | Thymidine kinase. (193 aa) |
| | rho | Putative transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (487 aa) |
| | tilS | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (451 aa) |
| | CSE_08660 | DNA glycosylase. (241 aa) |
| | CSE_08760 | Putative ribonuclease. (132 aa) |
| | CSE_08840 | Putative transposase for insertion sequence element. (556 aa) |
| | CSE_09140 | Hypothetical protein. (255 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (852 aa) |
| | CSE_09600 | Putative deoxyribonuclease. (263 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. (634 aa) |
| | CSE_09840 | Putative transposase; Fragment. (173 aa) |
| | CSE_09990 | Hypothetical protein. (158 aa) |
| | asnS | asparaginyl-tRNA synthetase; Protein synonym:asparagine--tRNA ligase. (427 aa) |
| | holA | Putative DNA polymerase III subunit delta. (332 aa) |
| | CSE_10070 | Putative tyrosine recombinase; Belongs to the 'phage' integrase family. (284 aa) |
| | CSE_10090 | Hypothetical protein. (678 aa) |
| | mutS2 | MutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (782 aa) |
| | CSE_10110 | Putative DNA polymerase family X. (554 aa) |
| | pheT | Protein synonym:phenylalanine--tRNA ligase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (797 aa) |
| | pheS | Protein synonym:phenylalanine--tRNA ligase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa) |
| | CSE_10260 | Putative transposase for insertion sequence element. (458 aa) |
| | CSE_10310 | Putative transposase; Fragment. (70 aa) |
| | CSE_10320 | Putative transposase; Fragment. (96 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (402 aa) |
| | priA | Protein synonym:ATP-dependent helicase PriA. (755 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (125 aa) |
| | CSE_10690 | Putative oligoribonuclease/3'-phosphoadenosine 5'-phosphate phosphatase; Bifunctional protein. (321 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (171 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (187 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (318 aa) |
| | nusG | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (182 aa) |
| | CSE_11030 | Putative RNA polymerase sigma factor; Belongs to the sigma-70 factor family. (176 aa) |
| | CSE_11040 | RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (252 aa) |
| | cysS | cysteinyl-tRNA synthetase; Protein synonym:cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (498 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (476 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (252 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (304 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1263 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1398 aa) |
| | CSE_11730 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa) |
| | mraW | S-adenosyl-L-methionine-dependent methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (291 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (878 aa) |
| | rluD | Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (303 aa) |
| | gcp | Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (335 aa) |
| | CSE_12220 | Hypothetical protein. (208 aa) |
| | CSE_12230 | Putative ATPase. (154 aa) |
| | CSE_12290 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (169 aa) |
| | CSE_12330 | Hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (237 aa) |
| | gltX-2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (441 aa) |
| | lysS | lysyl-tRNA synthetase; Protein synonym:lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (496 aa) |
| | CSE_12480 | Putative tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (326 aa) |
| | CSE_12510 | Putative transposase for insertion sequence element. (556 aa) |
| | CSE_12550 | Hypothetical protein. (127 aa) |
| | CSE_12640 | Hypothetical protein. (432 aa) |
| | trmFO | methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase TrmFO; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (425 aa) |
| | thrS | threonyl-tRNA synthetase; Protein synonym:threonine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (635 aa) |
| | topB | DNA topoisomerase III. (799 aa) |
| | CSE_12780 | Putative ATPase. (397 aa) |
| | smc | Chromosome partition protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1078 aa) |
| | nth | Putative DNA glycosylase/AP lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (218 aa) |
| | dnaE | DNA polymerase III alpha subunit. (1148 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (434 aa) |
| | dnaN | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa) |
| | recF | Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (357 aa) |
| | rsmG | Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (241 aa) |
| | CSE_00400 | Putative transposase. (472 aa) |
| | CSE_00540 | Putative transposase. (472 aa) |
| | CSE_00600 | RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa) |
| | hup | DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa) |
| | CSE_00740 | Putative DNA-binding protein; Belongs to the bacterial histone-like protein family. (78 aa) |
| | CSE_00760 | Putative replication protein. (259 aa) |
| | CSE_01090 | Putative transposase for insertion sequence element. (324 aa) |
| | CSE_01190 | Putative transposase; Fragment. (133 aa) |
| | CSE_01200 | Putative transposase; Fragment. (115 aa) |
| | CSE_01220 | Putative transposase for insertion sequence element. (556 aa) |
| | CSE_01390 | Hypothetical protein. (504 aa) |
| | CSE_01470 | Putative transposase; Fragment. (96 aa) |
| | CSE_01480 | Putative transposase; Fragment. (70 aa) |
| | CSE_01650 | Hypothetical protein. (260 aa) |
| | nrdD | Protein synonym:class III ribonucleotide reductase. (687 aa) |
| | hup-2 | DNA-binding protein HU; Belongs to the bacterial histone-like protein family. (91 aa) |
| | sbcD | Putative exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (386 aa) |
