STRINGSTRING
GU3_13990 GU3_13990 GU3_13535 GU3_13535 cheB cheB tadA tadA GU3_12605 GU3_12605 purU purU ansA ansA nagA nagA ribA ribA astE astE astB astB folE folE aguA aguA GU3_10930 GU3_10930 GU3_10730 GU3_10730 cobB cobB hisH hisH hisI hisI dcd dcd GU3_09550 GU3_09550 ureC ureC ureB ureB ureA ureA purU-3 purU-3 dapE dapE GU3_08385 GU3_08385 purU-2 purU-2 GU3_08060 GU3_08060 GU3_07735 GU3_07735 GU3_07715 GU3_07715 folD folD GU3_04485 GU3_04485 GU3_04670 GU3_04670 nadE nadE GU3_04900 GU3_04900 GU3_04975 GU3_04975 hutI hutI GU3_05400 GU3_05400 GU3_05725 GU3_05725 GU3_05755 GU3_05755 glsA glsA def def GU3_00185 GU3_00185 GU3_00205 GU3_00205 pyrC pyrC GU3_00990 GU3_00990 GU3_01115 GU3_01115 GU3_01240 GU3_01240 hutG hutG GU3_01530 GU3_01530 pxpA pxpA GU3_02660 GU3_02660 GU3_02860 GU3_02860 GU3_07380 GU3_07380 GU3_03225 GU3_03225 GU3_03980 GU3_03980 lpxC lpxC GU3_15930 GU3_15930 GU3_15820 GU3_15820 GU3_15815 GU3_15815 allA allA cobB-2 cobB-2 GU3_15355 GU3_15355 GU3_15145 GU3_15145 pyrG pyrG GU3_15080 GU3_15080 puuD puuD GU3_14485 GU3_14485 purH purH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GU3_13990Peptidoglycan hydrolase; COG3951 Rod binding protein. (128 aa)
GU3_13535Flagellar rod assembly protein/muramidase FlgJ; COG3951 Rod binding protein. (323 aa)
cheBChemotaxis-specific methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (379 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (163 aa)
GU3_12605Hypothetical protein; COG0590 Cytosine/adenosine deaminases. (164 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (278 aa)
ansACOG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D. (339 aa)
nagACOG1820 N-acetylglucosamine-6-phosphate deacetylase. (380 aa)
ribAGTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (199 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (341 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (444 aa)
folECOG0302 GTP cyclohydrolase I. (218 aa)
aguACOG2957 Peptidylarginine deiminase and related enzymes. (356 aa)
GU3_10930Putative carbon-nitrogen hydrolase; COG0388 Predicted amidohydrolase. (296 aa)
GU3_10730ThiJ/PfpI family protein; COG0693 Putative intracellular protease/amidase. (226 aa)
cobBCOG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily. (244 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa)
hisIBifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; COG0139 Phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (202 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (193 aa)
GU3_09550Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (341 aa)
ureCUrease subunit alpha; COG0804 Urea amidohydrolase (urease) alpha subunit. (568 aa)
ureBUrease subunit beta; COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family. (106 aa)
ureAUrease subunit gamma; COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. (100 aa)
purU-3Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)
GU3_08385Dihydropyrimidinase; COG0044 Dihydroorotase and related cyclic amidohydrolases. (473 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
GU3_08060Succinate dehydrogenase subunit; COG3608 Predicted deacylase. (333 aa)
GU3_07735COG1335 Amidases related to nicotinamidase. (222 aa)
GU3_07715COG1335 Amidases related to nicotinamidase. (232 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
GU3_04485COG0590 Cytosine/adenosine deaminases. (191 aa)
GU3_04670Sodium-type flagellar motor component; COG0790 FOG: TPR repeat, SEL1 subfamily. (222 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (540 aa)
GU3_04900Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (241 aa)
GU3_04975COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (135 aa)
hutICOG1228 Imidazolonepropionase and related amidohydrolases. (401 aa)
GU3_05400COG0860 N-acetylmuramoyl-L-alanine amidase. (438 aa)
GU3_05725Peptidase C26; COG2071 Predicted glutamine amidotransferases. (229 aa)
GU3_05755Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa)
glsACOG2066 Glutaminase; Belongs to the glutaminase family. (304 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa)
GU3_00185COG2071 Predicted glutamine amidotransferases. (249 aa)
GU3_00205COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. (368 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa)
GU3_00990COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases. (383 aa)
GU3_01115Hypothetical protein. (121 aa)
GU3_01240COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization. (283 aa)
hutGFormimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (316 aa)
GU3_01530Hypothetical protein; COG0685 5,10-methylenetetrahydrofolate reductase. (229 aa)
pxpALamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (248 aa)
GU3_02660COG1816 Adenosine deaminase. (334 aa)
GU3_02860Hypothetical protein. (220 aa)
GU3_07380Hypothetical protein; COG3608 Predicted deacylase. (339 aa)
GU3_03225Hypothetical protein; COG0438 Glycosyltransferase. (589 aa)
GU3_03980Hydroxydechloroatrazine ethylaminohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. (447 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (307 aa)
GU3_15930Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (436 aa)
GU3_15820COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (117 aa)
GU3_15815Hypothetical protein; COG0726 Predicted xylanase/chitin deacetylase. (306 aa)
allAUreidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (169 aa)
cobB-2Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (275 aa)
GU3_15355N-acetyl-anhydromuranmyl-L-alanine amidase; COG3023 Negative regulator of beta-lactamase expression. (182 aa)
GU3_15145Transcriptional activator TenA; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (222 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
GU3_15080CinA domain-containing protein; COG1546 Uncharacterized protein (competence- and mitomycin-induced); Belongs to the CinA family. (168 aa)
puuDGamma-glutamyl-gamma-aminobutyrate hydrolase; COG2071 Predicted glutamine amidotransferases. (254 aa)
GU3_14485Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase. (215 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (527 aa)
Your Current Organism:
Oceanimonas sp. GK1
NCBI taxonomy Id: 511062
Other names: O. sp. GK1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.