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opgE opgE opgC opgC opgG opgG opgH opgH ycfJ ycfJ ydbH ydbH ydcJ ydcJ opgD opgD ydgD ydgD tqsA tqsA ydgA ydgA yeeA yeeA sbmC sbmC asmA asmA nudI nudI ypfG ypfG sseB sseB aaeB aaeB aaeA aaeA aaeX aaeX yhfA yhfA yhfK yhfK tsgA tsgA yhjD yhjD yhjG yhjG yicH yicH opgB opgB yhdP yhdP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
opgEOPG biosynthetic transmembrane phosphoethanolamine transferase; Catalyzes the addition of a phosphoethanolamine moiety to the osmoregulated periplasmic glucan (OPG) backbone. (527 aa)
opgCOPG biosynthetic transmembrane succinyltransferase; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (385 aa)
opgGOPG biosynthetic periplasmic beta-1,6 branching glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs); Belongs to the OpgD/OpgG family. (511 aa)
opgHOPG biosynthetic ACP-dependent transmembrane UDP-glucose beta-1,2 glycosyltransferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (847 aa)
ycfJUncharacterized protein. (179 aa)
ydbHPutative membrane-anchored protein, function unknown. (879 aa)
ydcJPutative metalloenzyme; To M.tuberculosis Rv3292. (447 aa)
opgDOPG biosynthetic periplasmic protein; Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs). (551 aa)
ydgDPutative peptidase; Belongs to the peptidase S1B family. (273 aa)
tqsAPheromone AI-2 transporter; Controls the transport of the quorum-sensing signal AI-2 either by enhancing its secretion or inhibiting its uptake and consequently represses biofilm formation and motility and affects the global gene expression in biofilms. (344 aa)
ydgADUF945 family protein. (502 aa)
yeeAPutative transporter, FUSC family inner membrane protein. (352 aa)
sbmCDNA gyrase inhibitor; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. Protects cells against the natural plasmid-encoded toxins microcin B17 (MccB17) and CcdB, and synthetic quinolones. Can also protect cells against alkylating agents that act independently of DNA gyrase, suggesting a more general role in protectin [...] (157 aa)
asmASuppressor of OmpF assembly mutants; Involved in the inhibition of assembly of mutant ompF proteins. In general, could be involved in the assembly of outer membrane proteins; Belongs to the AsmA family. (617 aa)
nudINucleoside triphosphatase; Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP). (141 aa)
ypfGDUF1176 family protein. (347 aa)
sseBRhodanase-like enzyme, sulfur transfer from thiosulfate; May be involved in the enhancement of serine-sensitivity. (258 aa)
aaeBP-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell. Substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. (655 aa)
aaeAP-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeB. (310 aa)
aaeXDUF1656 family putative inner membrane efflux pump associated protein; Belongs to the AaeX family. (67 aa)
yhfAOsmC family protein. (134 aa)
yhfKPutative transporter, FUSC superfamily inner membrane protein; Protein involved in metabolic process. (700 aa)
tsgAPutative transport; Belongs to the major facilitator superfamily. TsgA family. (393 aa)
yhjDInner membrane putative BrbK family alternate lipid exporter. (337 aa)
yhjGPutative inner membrane-anchored periplasmic AsmA family protein. (686 aa)
yicHPutative inner membrane-anchored periplasmic AsmA family protein; Belongs to the AsmA family. (569 aa)
opgBOPG periplasmic biosynthetic phosphoglycerol transferases I (membrane-bound) and II (soluble); Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones. Belongs to the OpgB family. (763 aa)
yhdPDUF3971-AsmA2 domains protein. (1266 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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