node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cutC | yecM | b1874 | b1875 | Copper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Putative metal-binding enzyme; To H.influenzae HI_1582/HI_1581. | 0.877 |
cytR | sxy | b3934 | b0959 | Anti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | 0.737 |
dcuC | ycdZ | b0621 | b1036 | Anaerobic C4-dicarboxylate transport; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. | DUF1097 family inner membrane protein. | 0.702 |
dcuC | yjjB | b0621 | b4363 | Anaerobic C4-dicarboxylate transport; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. | DUF3815 family inner membrane protein. | 0.728 |
dcuC | yjjP | b0621 | b4364 | Anaerobic C4-dicarboxylate transport; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. | DUF1212 family inner membrane protein; Putative structural protein; To H.influenzae HI_0108. | 0.724 |
sxy | cytR | b0959 | b3934 | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | Anti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. | 0.737 |
sxy | yafD | b0959 | b0209 | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | Endo/exonuclease/phosphatase family protein. | 0.451 |
sxy | ycdY | b0959 | b1035 | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.571 |
yafC | yafD | b0208 | b0209 | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | Endo/exonuclease/phosphatase family protein. | 0.683 |
yafD | sxy | b0209 | b0959 | Endo/exonuclease/phosphatase family protein. | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | 0.451 |
yafD | yafC | b0209 | b0208 | Endo/exonuclease/phosphatase family protein. | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. | 0.683 |
yafD | ycdY | b0209 | b1035 | Endo/exonuclease/phosphatase family protein. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.514 |
yafD | yecM | b0209 | b1875 | Endo/exonuclease/phosphatase family protein. | Putative metal-binding enzyme; To H.influenzae HI_1582/HI_1581. | 0.435 |
yafD | yggL | b0209 | b2959 | Endo/exonuclease/phosphatase family protein. | DUF469 family protein; To H.influenzae HI_0341. | 0.510 |
yafD | yheO | b0209 | b3346 | Endo/exonuclease/phosphatase family protein. | Putative PAS domain-containing DNA-binding transcriptional regulator; To H.influenzae HI_0575. | 0.471 |
ycdX | ycdY | b1034 | b1035 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | 0.998 |
ycdX | ycdZ | b1034 | b1036 | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | DUF1097 family inner membrane protein. | 0.845 |
ycdY | sxy | b1035 | b0959 | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | CRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. | 0.571 |
ycdY | yafD | b1035 | b0209 | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | Endo/exonuclease/phosphatase family protein. | 0.514 |
ycdY | ycdX | b1035 | b1034 | Redox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. | Alkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. | 0.998 |