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yafC yafC yafD yafD dcuC dcuC sxy sxy ycdX ycdX ycdY ycdY ycdZ ycdZ cutC cutC yecM yecM yggL yggL yheO yheO yidE yidE cytR cytR yjjA yjjA yjjB yjjB yjjP yjjP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yafCPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (304 aa)
yafDEndo/exonuclease/phosphatase family protein. (266 aa)
dcuCAnaerobic C4-dicarboxylate transport; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. (461 aa)
sxyCRP-S-dependent promoter expression factor; Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation. Induction of the CRP-S regulon also requires Sxy- activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP. Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs. (209 aa)
ycdXAlkaline phosphatase; Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro. Involved in the swarming motility process; Belongs to the PHP family. (245 aa)
ycdYRedox enzyme maturation protein (REMP) chaperone for YcdX; Acts as a chaperone that increases YcdX activity, maybe by facilitating the correct insertion of the zinc ions into the catalytic site of YcdX. Involved in the swarming motility process. (184 aa)
ycdZDUF1097 family inner membrane protein. (163 aa)
cutCCopper homeostasis protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (248 aa)
yecMPutative metal-binding enzyme; To H.influenzae HI_1582/HI_1581. (188 aa)
yggLDUF469 family protein; To H.influenzae HI_0341. (108 aa)
yheOPutative PAS domain-containing DNA-binding transcriptional regulator; To H.influenzae HI_0575. (240 aa)
yidEPutative transport protein. (553 aa)
cytRAnti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. (341 aa)
yjjAPutative DUF2501 family periplasmic protein; Putative glycoprotein/receptor. (164 aa)
yjjBDUF3815 family inner membrane protein. (157 aa)
yjjPDUF1212 family inner membrane protein; Putative structural protein; To H.influenzae HI_0108. (256 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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