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| | thiQ | Thiamine/thiamine pyrophosphate ABC transporter ATPase; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system (Probable); Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa) |
| | thiP | Thiamine/thiamine pyrophosphate ABC transporter permease; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (536 aa) |
| | thiB | Thiamine/thiamine pyrophosphate/thiamine monophosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Binds thiamine, thiamine phosphate and thiamine diphosphate with high affinity ; Belongs to the bacterial solute-binding protein 1 family. (327 aa) |
| | fhuC | Iron(3+)-hydroxamate import ABC transporter ATPase; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system. (265 aa) |
| | fhuD | Iron(3+)-hydroxamate import ABC transporter periplasmic binding protein; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of all iron(3+)-hydroxamate siderophores such as ferrichrome, gallichrome, desferrioxamine, coprogen, aerobactin, shizokinen, rhodotorulic acid and the antibiotic albomycin. (296 aa) |
| | fhuB | Iron(3+)-hydroxamate import ABC transporter permease; Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane. (660 aa) |
| | btuF | Vitamin B12 ABC transporter periplasmic binding protein; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa) |
| | mtn | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5- deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited by 5'-deoxyadenosine accumulati [...] (232 aa) |
| | metQ | DL-methionine transporter subunit; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Belongs to the NlpA lipoprotein family. (271 aa) |
| | metI | DL-methionine transporter subunit; Part of the binding-protein-dependent transport system for D- methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane. (217 aa) |
| | metN | DL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. It has also been shown to be involved in formyl-L-methionine transport. Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (343 aa) |
| | afuC | CP4-6 prophage; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system. (348 aa) |
| | tauA | Taurine ABC transporter periplasmic binding protein; Part of a binding-protein-dependent transport system for taurine. (320 aa) |
| | tauB | Taurine ABC transporter ATPase; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system. (255 aa) |
| | tauC | Taurine ABC transporter permease; Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (275 aa) |
| | tauD | Taurine dioxygenase, 2-oxoglutarate-dependent; Catalyzes the alpha-ketoglutarate-dependent hydroxylation of taurine yielding sulfite and aminoacetaldehyde after decomposition of an unstable intermediate. Is required for the utilization of taurine (2-aminoethanesulfonate) as an alternative sulfur source for growth in the absence of sulfate. To a lesser extent, pentanesulfonate, 3-(N-morpholino)propanesulfonate and 1,3-dioxo-2-isoindolineethanesulfonate are also desulfonated by this enzyme in vitro; however, desulfonation by TauD of organosulfonates other than taurine seem to be of littl [...] (283 aa) |
| | gltL | Glutamate/aspartate ABC transporter ATPase; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for energy coupling to the transport system. (241 aa) |
| | gltK | Glutamate/aspartate ABC transporter permease; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane. (224 aa) |
| | gltJ | Glutamate/aspartate ABC transporter permease; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane. (246 aa) |
| | gltI | Glutamate/aspartate periplasmic binding protein; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate. (302 aa) |
| | modF | Molybdate ABC transporter ATPase; Probably not involved in the transport of molybdenum into the cell; Belongs to the ABC transporter superfamily. (490 aa) |
| | modE | Transcriptional repressor for the molybdenum transport operon modABC; Functions as an intracellular molybdate sensor. The ModE-Mo complex acts as a repressor of the modABC operon, which is involved in the transport of molybdate. Binds modA promoter DNA in the absence of molybdate, however molybdate binding confers increased DNA affinity. Binds the promoter of moaA activating its transcription; binding is not enhanced by molybdate. The protein dimer binds the consensus palindrome sequence 5'-TATAT-N7-TAYAT-3' and a variant 5'-TGTGT-N7-TGYGT-3'. Acts as a regulator of the expression of 6 [...] (262 aa) |
| | modA | Molybdate ABC transporter periplasmic binding protein; Part of the ABC transporter complex ModABC involved in the transport of molybdenum into the cell. Binds molybdate with high affinity in vitro and with a similar affinity in vivo. Binds tungstate with high affinity in vitro. Binds unnatural anion perrhenate with high affinity in vitro. Does not bind sulfate, phosphate, arsenate, selenate, chlorate, metavanadate, nitrate, perchlorate, permanganate or carbonate. Belongs to the bacterial solute-binding protein ModA family. (257 aa) |
| | modB | Molybdate ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (229 aa) |
| | modC | Molybdate ABC transporter ATPase; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa) |
| | ybhA | Pyridoxal phosphate (PLP) phosphatase; Catalyzes the dephosphorylation of pyridoxal-phosphate (PLP). Can also hydrolyze erythrose-4-phosphate (Ery4P) and fructose-1,6-bis- phosphate (Fru1,6bisP); Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (272 aa) |
| | ybhR | Putative ABC transporter permease; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family. (368 aa) |
| | ybhS | Putative ABC transporter permease; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family. (377 aa) |
| | ybhF | Putative ABC transporter ATPase; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably responsible for energy coupling to the transport system. (578 aa) |
| | ybhG | Putative membrane fusion protein (MFP) component of efflux pump, membrane anchor; Could be involved in the sensitivity control to chloramphenicol; Belongs to the UPF0194 family. (332 aa) |
| | ybiH | DUF1956 domain-containing tetR family putative transcriptional regulator; Regulates transcription of the cecR-ybhGFSR operon and the rhlE gene, which altogether are involved in the control of sensitivity to cefoperazone and chloramphenicol. Represses the cecR-ybhGFSR operon and activates the rhlE operon. Acts by binding to a palindromic sequence within the intergenic spacer located between these two divergently transcribed operons. (223 aa) |
| | glnQ | Glutamine transporter subunit; Part of the binding-protein-dependent transport system for glutamine. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (240 aa) |
| | glnP | Glutamine transporter subunit; Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane. (219 aa) |
| | glnH | Glutamine transporter subunit; Involved in a glutamine-transport system GlnHPQ. (248 aa) |
| | iaaA | Isoaspartyl peptidase; Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues). Degrades L-isoaspartyl-containing di- and maybe also tripeptides. Also has L-asparaginase activity, although this may not be its principal function. Belongs to the Ntn-hydrolase family. (321 aa) |
| | gsiA | Glutathione ABC transporter ATPase; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system. (623 aa) |
| | gsiB | Glutathione ABC transporter periplasmic binding protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Binds glutathione ; Belongs to the bacterial solute-binding protein 5 family. (512 aa) |
| | gsiC | Glutathione ABC transporter permease; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane. (306 aa) |
| | gsiD | Glutathione ABC transporter permease; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane. (303 aa) |
| | potF | Putrescine ABC transporter periplasmic binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine. Polyamine binding protein. Belongs to the bacterial solute-binding protein PotD/PotF family. (370 aa) |
| | potG | Putrescine ABC transporter ATPase; Part of the binding-protein-dependent transport system for putrescine. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (377 aa) |
| | potH | Putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (317 aa) |
| | potI | Putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (281 aa) |
| | artJ | Arginine ABC transporter periplasmic binding protein; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Binds L-arginine with high affinity. (243 aa) |
| | artM | Arginine ABC transporter permease; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane. (222 aa) |
| | artQ | Arginine ABC transporter permease; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane. (238 aa) |
| | artI | Arginine transporter subunit; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. (243 aa) |
| | artP | Arginine ABC transporter ATPase; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for energy coupling to the transport system. (242 aa) |
| | cydC | Glutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system; Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3.A.1.129.1) family. (573 aa) |
| | cydD | Glutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system. (588 aa) |
| | msbA | Lipid ABC transporter permease/ATPase; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family. (582 aa) |
| | ssuB | Aliphatic sulfonate ABC transporter ATPase; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable). (255 aa) |
| | ssuC | Aliphatic sulfonate ABC transporter permease; Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (263 aa) |
| | ssuD | Alkanesulfonate monooxygenase, FMNH(2)-dependent; Involved in desulfonation of aliphatic sulfonates. Catalyzes the conversion of pentanesulfonic acid to sulfite and pentaldehyde and is able to desulfonate a wide range of sulfonated substrates including C-2 to C-10 unsubstituted linear alkanesulfonates, substituted ethanesulfonic acids and sulfonated buffers; Belongs to the SsuD family. (381 aa) |
| | ssuA | Aliphatic sulfonate ABC transporter periplasmic binding protein; Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein; Belongs to the bacterial solute-binding protein SsuA/TauA family. (319 aa) |
| | ssuE | NAD(P)H-dependent FMN reductase; Catalyzes an NADPH-dependent reduction of FMN, but is also able to reduce FAD or riboflavin. (191 aa) |
| | potD | Spermidine/putrescine ABC transporter periplasmic binding protein; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine. Polyamine binding protein; Belongs to the bacterial solute-binding protein PotD/PotF family. (348 aa) |
| | potC | Spermidine/putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (264 aa) |
| | potB | Spermidine/putrescine ABC transporter permease; Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (275 aa) |
| | potA | Spermidine/putrescine ABC transporter ATPase; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | oppA | Oligopeptide ABC transporter periplasmic binding protein; This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity; Belongs to the bacterial solute-binding protein 5 family. (543 aa) |
| | oppB | Oligopeptide ABC transporter permease; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (306 aa) |
| | oppC | Oligopeptide ABC transporter permease; Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (302 aa) |
| | oppD | Oligopeptide ABC transporter ATPase; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. (337 aa) |
| | oppF | Oligopeptide ABC transporter ATPase; Part of the binding-protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (334 aa) |
| | sapF | Antimicrobial peptide ABC transporter ATPase; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. Does not stimulate K(+) uptake ability of TrkH on its own, but increases K(+) uptake by 20% in the presence of SapD; has no effect of TrkG ; Belongs to the ABC transporter superfamily. (268 aa) |
| | sapD | Antimicrobial peptide ABC transporter ATPase; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. Stimulates K(+)-uptake proteins TrkG and TrkH to import K(+), may act via ATP-binding rather than ATP hydrolysis. (330 aa) |
| | sapC | Antimicrobial peptide transport ABC transporter permease; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. (296 aa) |
| | sapB | Antimicrobial peptide transport ABC transporter permease; Part of a putrescine export transport system, does not play a role in resistance to antimicrobial peptides. (321 aa) |
| | sapA | Antimicrobial peptide transport ABC transporter periplasmic binding protein; Not part of a putrescine export system. Very similar to a S.typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E.coli is implicated in putrescine export. (547 aa) |
| | mppA | Murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit; Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system; Belongs to the bacterial solute-binding protein 5 family. (537 aa) |
| | ydcS | Putative ABC transporter periplasmic binding protein; Catalyzes the formation of short polymers of R-3- hydroxybutyrate (cPHB). Involved in natural transformation. Probably part of the ABC transporter complex YdcSTUV. During natural transformation, may bind dsDNA and convey it to the inner membrane channel formed by YdcV (Probable). Belongs to the bacterial solute-binding protein PotD/PotF family. (381 aa) |
| | ydcT | Putative ABC transporter ATPase; Probably part of the ABC transporter complex YdcSTUV. Probably responsible for energy coupling to the transport system. (337 aa) |
| | ydcU | Putative ABC transporter permease; Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane. (313 aa) |
| | ydcV | Putative ABC transporter permease; Involved in natural transformation. Probably part of the ABC transporter complex YdcSTUV. Probably responsible for the translocation of the substrate across the membrane. During natural transformation, may serve as the channel for dsDNA uptake (Probable). (264 aa) |
| | ddpF | D,D-dipeptide ABC transporter ATPase; Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for energy coupling to the transport system. (308 aa) |
| | ddpD | D,D-dipeptide ABC transporter ATPase; Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for energy coupling to the transport system. (328 aa) |
| | ddpC | D,D-dipeptide ABC transporter permease; Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (298 aa) |
| | ddpB | D,D-dipeptide ABC transporter permease; Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (340 aa) |
| | ddpA | D,D-dipeptide ABC transporter periplasmic binding protein; Part of the ABC transporter complex DdpABCDF, which is probably involved in D,D-dipeptide transport; Belongs to the bacterial solute-binding protein 5 family. (516 aa) |
| | lsrK | Autoinducer-2 kinase; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. Required for the regulation of the lsr operon and many other genes. (530 aa) |
| | lsrR | Lsr operon transcriptional repressor; Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI-2, LsrR is inactivated by binding phospho-AI-2, leading to the transcription of the lsr genes. (317 aa) |
| | lsrA | Autoinducer 2 import ATP-binding protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system (Probable). This protein is essential for aerobic growth. (511 aa) |
| | lsrC | Autoinducer 2 import system permease protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (342 aa) |
| | lsrD | Autoinducer 2 import system permease protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (330 aa) |
| | lsrB | Autoinducer 2-binding protein; Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (Probable); Belongs to the bacterial solute-binding protein 2 family. (340 aa) |
| | lsrF | Putative autoinducer-2 (AI-2) aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family. (291 aa) |
| | lsrG | Autoinducer-2 (AI-2) degrading protein LsrG; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD). (96 aa) |
| | tam | Trans-aconitate methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate at high affinity and of cis-aconitate, isocitrate, and citrate at lower velocities and affinities; Belongs to the methyltransferase superfamily. Tam family. (252 aa) |
| | yneE | Bestrophin family putative inner membrane protein. (304 aa) |
| | btuD | Vitamin B12 ABC transporter ATPase; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | btuC | Vitamin B12 ABC transporter permease; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (326 aa) |
| | araG | L-arabinose ABC transporter ATPase; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system (Probable); Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa) |
| | araF | L-arabinose ABC transporter periplasmic binding protein; Involved in the high-affinity L-arabinose membrane transport system. Binds with high affinity to arabinose, but can also bind D- galactose (approximately 2-fold reduction) and D-fucose (approximately 40-fold reduction). (329 aa) |
| | yecC | Putative ABC transporter ATPase; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Probably responsible for energy coupling to the transport system (Probable). (250 aa) |
| | yecS | ABC family putative inner membrane permease; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Probably responsible for the translocation of the substrate across the membrane (Probable). (222 aa) |
| | dcyD | D-cysteine desulfhydrase, PLP-dependent; Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine. Can also catalyze the degradation of 3-chloro-D- alanine. (328 aa) |
| | fliY | Cystine transporter subunit; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Binds cystine ; Belongs to the bacterial solute-binding protein 3 family. (266 aa) |
| | yehW | Putative ABC transporter permease; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (243 aa) |
| | yehX | Putative ABC transporter ATPase; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for energy coupling to the transport system. (308 aa) |
| | yehY | Putative ABC transporter permease; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for the translocation of the substrate across the membrane. (385 aa) |
| | osmF | Putative ABC transporter periplasmic binding protein; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Binds glycine betaine with low affinity. Belongs to the OsmX family. (305 aa) |
| | mglC | Methyl-galactoside transporter subunit; Part of the binding-protein-dependent transport system for galactoside. Probably responsible for the translocation of the substrate across the membrane. (336 aa) |
| | mglA | Methyl-galactoside ABC transporter ATPase; Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system (Probable). (506 aa) |
| | mglB | Methyl-galactoside transporter subunit; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor. (332 aa) |
| | yejA | Periplasmic-binding component of ABC superfamily; To H.influenzae HbpA. (604 aa) |
| | yejB | Microcin C ABC transporter permease; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (364 aa) |
| | yejE | Microcin C ABC transporter permease; Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (341 aa) |
| | yejF | Microcin C ABC transporter ATPase; Putative ATP-binding component of a transport system. (529 aa) |
| | yojI | Microcin J25 efflux ABC transporter permease/ATPase; Mediates resistance to the antibacterial peptide microcin J25, when expressed from a multicopy vector. Functions as an efflux pump for microcin J25, with the help of the outer membrane channel TolC. (547 aa) |
| | hisP | Histidine ABC transporter ATPase; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Responsible for energy coupling to the transport system (By similarity). (257 aa) |
| | hisM | Histidine ABC transporter permease; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity). (238 aa) |
| | hisQ | Histidine ABC transporter permease; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity). (228 aa) |
| | hisJ | Histidine ABC transporter periplasmic binding protein; Part of the histidine permease ABC transporter. Binds histidine. Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation (By similarity). (260 aa) |
| | argT | Lysine/arginine/ornithine transporter subunit; Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP (By similarity). (260 aa) |
| | yphD | Putative sugar ABC transporter permease; Probably part of the binding-protein-dependent transport system YphDEF. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (332 aa) |
| | yphE | Putative sugar ABC transporter ATPase; Probably part of a binding-protein-dependent transport system YphDEF. Probably responsible for energy coupling to the transport system. (503 aa) |
| | yphF | Putative sugar ABC transporter periplasmic binding protein; Probably part of the binding-protein-dependent transport system YphDEF; Belongs to the bacterial solute-binding protein 2 family. (327 aa) |
| | proV | Glycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system (Probable). (400 aa) |
| | proW | Glycine betaine/proline ABC transporter permease; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa) |
| | proX | Glycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. (330 aa) |
| | luxS | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (171 aa) |
| | ygiS | Putative ABC transporter permease; Probably part of a deoxycholate transport system. Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum. Belongs to the bacterial solute-binding protein 5 family. (535 aa) |
| | yhdX | Putative amino-acid ABC transporter permease protein YhdX; Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily. (393 aa) |
| | yhdY | Putative amino acid ABC transporter permease; Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily. (367 aa) |
| | yhdZ | Putative amino acid ABC transporter ATPase; Probably part of a binding-protein-dependent transport system YdhWXYZ for an amino acid. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (252 aa) |
| | ugpQ | Glycerophosphodiester phosphodiesterase, cytosolic; Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols. (247 aa) |
| | ugpC | Sn-glycerol-3-phosphate ABC transporter ATPase; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters. (356 aa) |
| | ugpE | Sn-glycerol-3-phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa) |
| | ugpA | Sn-glycerol-3-phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa) |
| | ugpB | Sn-glycerol-3-phosphate ABC transporter periplasmic binding protein; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa) |
| | livF | Branched-chain amino acid ABC transporter ATPase; Component of the leucine-specific transport system. (237 aa) |
| | livG | Branched-chain amino acid ABC transporter ATPase; Component of the leucine-specific transport system. (255 aa) |
| | livM | Branched-chain amino acid ABC transporter permease; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily. (425 aa) |
| | livH | Branched-chain amino acid ABC transporter permease; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily. (308 aa) |
| | livK | Leucine transporter subunit; This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids in E.coli; Belongs to the leucine-binding protein family. (369 aa) |
| | livJ | Branched-chain amino acid ABC transporter periplasmic binding protein; This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high- affinity transport of the branched-chain amino acids; Belongs to the leucine-binding protein family. (367 aa) |
| | nikA | Nickel/heme ABC transporter periplasmic binding protein; Involved in a nickel transport system, probably represents the nickel binder. (524 aa) |
| | nikB | Nickel ABC transporter permease; Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane. (314 aa) |
| | nikC | Nickel ABC transporter permease; Involved in a nickel transport system, probably translocates nickel through the bacterial inner membrane. (277 aa) |
| | nikD | Nickel ABC transporter ATPase; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (254 aa) |
| | nikE | Nickel ABC transporter ATPase; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa) |
| | nikR | Transcriptional repressor, Ni-binding; Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel; Belongs to the transcriptional regulatory CopG/NikR family. (133 aa) |
| | yhhJ | Putative transporter. (374 aa) |
| | rbbA | Ribosome-associated ATPase: ATP-binding protein/ATP-binding membrane protein; Exhibits an intrinsic ATPase activity that is stimulated by both 70S ribosomes and 30S ribosomal subunits. Could be involved in protein-chain elongation and in release of deacyl-tRNA from ribosomes after peptide bond synthesis. Stimulates the synthesis of polyphenylalanine in vitro; In the C-terminal section; belongs to the ABC-2 integral membrane protein family. (911 aa) |
| | yhiI | Putative membrane fusion protein (MFP) of efflux pump; Putative membrane protein. (355 aa) |
| | dppF | Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (334 aa) |
| | dppD | Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. (327 aa) |
| | dppC | Dipeptide/heme ABC transporter permease; Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (300 aa) |
| | dppB | Dipeptide/heme ABC transporter permease; Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily. (339 aa) |
| | dppA | Dipeptide/heme ABC transporter periplasmic binding protein; Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis; Belongs to the bacterial solute-binding protein 5 family. (535 aa) |
| | nlpA | Cytoplasmic membrane lipoprotein-28; Lipoprotein-28. (272 aa) |
| | rbsD | D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. It also catalyzes the conversion between beta- allofuranose and beta-allopyranose; Belongs to the RbsD / FucU family. RbsD subfamily. (139 aa) |
| | rbsA | D-ribose ABC transporter ATPase; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa) |
| | rbsC | D-ribose ABC transporter permease; Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane. (321 aa) |
| | rbsB | D-ribose ABC transporter periplasmic binding protein; Part of the ABC transporter complex RbsABC involved in ribose import. Binds ribose. Also serves as the primary chemoreceptor for chemotaxis; Belongs to the bacterial solute-binding protein 2 family. (296 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily. (309 aa) |
| | rbsR | Transcriptional repressor of ribose metabolism; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon. (330 aa) |
| | malG | Maltose transporter subunit; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (296 aa) |
| | malF | Maltose transporter subunit; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. (514 aa) |
| | malE | Maltose transporter subunit; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins such as maltotriose. Belongs to the bacterial solute-binding protein 1 family. (396 aa) |
| | malK | Maltose ABC transportor ATPase; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (371 aa) |
| | lamB | Maltose outer membrane porin (maltoporin); Involved in the transport of maltose and maltodextrins, indispensable for translocation of dextrins containing more than three glucosyl moieties. A hydrophobic path ('greasy slide') of aromatic residues serves to guide and select the sugars for transport through the channel. Also acts as a receptor for several bacteriophages including lambda. (446 aa) |
| | malM | Maltose regulon periplasmic protein; Not yet known. Might function in the uptake of a still unidentified substrate; To S.typhimurium MalM. (306 aa) |
| | ytfQ | Galactofuranose ABC transporter periplasmic binding protein; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Binds to both alpha- and beta- galactofuranose. (318 aa) |
| | ytfT | Putative sugar ABC transporter permease; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable). Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily. (341 aa) |
| | yjfF | Putative sugar ABC transporter permease; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Probably responsible for the translocation of the substrate across the membrane (Probable). (331 aa) |
| | araH | L-arabinose ABC transporter permease; Part of the binding-protein-dependent transport system for L- arabinose. Probably responsible for the translocation of the substrate across the membrane. (328 aa) |
| | ytfR | Putative sugar ABC transporter ATPase; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Responsible for energy coupling to the transport system (Probable). (500 aa) |
