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| | yahO | Periplasmic protein, function unknown, YhcN family. (91 aa) |
| | psiF | PsiF family protein; Induced by phosphate starvation; Protein involved in phosphorus metabolic process and response to starvation. (106 aa) |
| | ybaY | Outer membrane lipoprotein; Glycoprotein/polysaccharide metabolism; Protein involved in lipoprotein biosynthetic process and glycoprotein biosynthetic process. (190 aa) |
| | ybaA | DUF1428 family protein. (117 aa) |
| | ylaC | DUF1449 family inner membrane protein. (156 aa) |
| | uspG | Universal stress protein UP12; Has intrinsic autoadenylation and autophosphorylation activities, probably on Ser or Thr residues. Belongs to the universal stress protein A family. (142 aa) |
| | ybeL | DUF1451 family protein; Putative alpha helical protein. (160 aa) |
| | ybgA | DUF1722 family protein. (169 aa) |
| | phr | Deoxyribodipyrimidine photolyase, FAD-binding; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. (472 aa) |
| | ybgS | Putative homeobox protein. (126 aa) |
| | ybhL | Putative acetate transporter; BAX Inhibitor-1 family inner membrane protein. (234 aa) |
| | ybhM | BAX Inhibitor-1 family inner membrane protein. (237 aa) |
| | dps | Fe-binding and storage protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and cop [...] (167 aa) |
| | ybjP | Putative lipoprotein. (171 aa) |
| | ybjQ | UPF0145 family protein. (107 aa) |
| | amiD | 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. (276 aa) |
| | ybjX | DUF535 family protein; Putative enzyme; To H.influenzae HI_0461. (330 aa) |
| | cspD | Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells. (74 aa) |
| | ycaC | Putative isochorismatase family hydrolase; Protein involved in cellular amino acid catabolic process. (208 aa) |
| | ycaD | Putative MFS transporter, inner membrane protein. (382 aa) |
| | ycaP | UPF0702 family putative inner membrane protein. (230 aa) |
| | yccJ | Uncharacterized protein. (75 aa) |
| | wrbA | NAD(P)H:quinone oxidoreductase; It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH. (198 aa) |
| | msyB | Multicopy suppressor of secY and secA; Could participate in the normal pathway of protein export. (124 aa) |
| | rimJ | ribosomal-protein-S5-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S5. Also plays a role in maturation of the 30S ribosomal subunit. Plays a role in the temperature regulation of pap pilin transcription. Belongs to the acetyltransferase family. RimJ subfamily. (194 aa) |
| | yceH | UPF0502 family protein; Belongs to the UPF0502 family. (215 aa) |
| | yceM | Putative virulence factor; Belongs to the Gfo/Idh/MocA family. (307 aa) |
| | murJ | Putative lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. Belongs to the MurJ/MviN family. (511 aa) |
| | ycgB | SpoVR family stationary phase protein; To B.subtilis SpoVR. (510 aa) |
| | ychH | DUF2583 family putative inner membrane protein. (92 aa) |
| | chaB | Cation transport regulator; Might be a regulator of the sodium-potassium/proton antiporter ChaA; Belongs to the ChaB family. (76 aa) |
| | yciE | Putative rubrerythrin/ferritin-like metal-binding protein. (168 aa) |
| | yciF | Putative structural proteins. (166 aa) |
| | yciG | KGG family protein; Belongs to the con-10 family. (59 aa) |
| | osmB | Osmotically and stress inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival. (72 aa) |
| | uspE | Stress-induced protein; Required for resistance to DNA-damaging agents. (316 aa) |
| | uspF | Universal stress protein F; Pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related. (144 aa) |
| | hslJ | Heat-inducible lipoprotein involved in novobiocin resistance; Heat shock protein hslJ; Protein involved in response to temperature stimulus. (140 aa) |
| | rimL | ribosomal-protein-L7/L12-serine acetyltransferase; This enzyme acetylates the N-terminal serine of ribosomal protein L7/L12. (179 aa) |
| | ydcK | Uncharacterized protein; Putative enzyme; Not classified; Belongs to the transferase hexapeptide repeat family. (326 aa) |
| | ydcZ | DUF606 family inner membrane protein. (149 aa) |
| | mnaT | Methionine N-acyltransferase; Acyltransferase that appears to be required for E.coli optimal growth rate and yield via the formation of N-acetylated amino acids. Catalyzes the acylation of L-methionine using acetyl-CoA or propanoyl-CoA as acyl donors, and the acetylation of L-phenylglycine. Is also able to N-acylate other free L-amino acids and their derivatives using a CoA thioester as cosubstrate. Using acetyl-CoA as an acyl donor, substrate specificity is methionine sulfone > methionine sulfoximine > methionine sulfoxide > methionine. Asparagine, lysine, glutamine, aspartate and glu [...] (172 aa) |
| | curA | Curcumin/dihydrocurcumin reductase, NADPH-dependent; Catalyzes the metal-independent reduction of curcumin to dihydrocurcumin (DHC) as an intermediate product, followed by further reduction to tetrahydrocurcumin (THC) as an end product. It also acts on 3-octene-2-one, 3-hepten-2-one, resveratrol, and trans-2-octenal. Belongs to the NADP-dependent oxidoreductase L4BD family. (345 aa) |
| | sra | Stationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family. (45 aa) |
| | bdm | Biofilm-dependent modulation protein. (71 aa) |
| | osmC | Lipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. (143 aa) |
| | ydhB | Putative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (310 aa) |
| | ydhC | Putative arabinose efflux transporter; Putative transport protein. (403 aa) |
| | cfa | Cyclopropane fatty acyl phospholipid synthase, SAM-dependent; Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge. (382 aa) |
| | ydhS | Putative oxidoreductase. (534 aa) |
| | osmE | Osmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress. (112 aa) |
| | yeaG | Protein kinase, endogenous substrate unidentified; autokinase; Belongs to the PrkA family. (644 aa) |
| | yeaH | UPF0229 family protein; Belongs to the UPF0229 family. (427 aa) |
| | yebV | Uncharacterized protein. (78 aa) |
| | uspC | Universal stress protein; Required for resistance to DNA-damaging agents. (142 aa) |
| | yedL | GNAT family putative N-acetyltransferase; Belongs to the acetyltransferase family. (159 aa) |
| | yodD | Uncharacterized protein. (75 aa) |
| | yedP | Putative mannosyl-3-phosphoglycerate phosphatase. (271 aa) |
| | yegP | UPF0339 family protein; Belongs to the UPF0339 family. Duplicated subfamily. (110 aa) |
| | yohC | Yip1 family inner membrane protein. (195 aa) |
| | yfcG | GSH-dependent disulfide bond oxidoreductase; Exhibits a very robust glutathione (GSH)-dependent disulfide- bond reductase activity toward the model substrate, 2-hydroxyethyl disulfide; the actual physiological substrates are not known. Has also a low GSH-dependent hydroperoxidase activity toward cumene hydroperoxide, but does not reduce H(2)O(2), tert-butyl hydroperoxide, benzyl peroxide, or lauroyl peroxide. Exhibits little or no GSH transferase activity with most typical electrophilic substrates, and has no detectable transferase activity using glutathionylspermidine (GspSH) as the n [...] (215 aa) |
| | ypeC | DUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. (108 aa) |
| | yfeY | RpoE-regulated lipoprotein. (191 aa) |
| | yfeZ | Inner membrane protein. (149 aa) |
| | ypeA | GNAT family putative N-acetyltransferase; Belongs to the acetyltransferase family. YpeA subfamily. (141 aa) |
| | tmcA | Elongator methionine tRNA (ac4C34) acetyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). It recognizes the wobble base of tRNA(Met), thus distinguishing between tRNA(Met) and the structurally similar tRNA(Ile2). (671 aa) |
| | ypfJ | Putative neutral zinc metallopeptidase. (287 aa) |
| | yphA | DoxX family inner membrane protein. (140 aa) |
| | pka | Protein lysine acetyltransferase; Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II. Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits. Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity. Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility. (886 aa) |
| | ygaU | Uncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+). May be involved in the regulation of peptidoglycan cross-linking. (149 aa) |
| | ygaM | Putative membrane-anchored DUF883 family ribosome-binding protein. (109 aa) |
| | ygdI | DUF903 family verified lipoprotein. (75 aa) |
| | ygeV | Putative transcriptional regulator; Protein involved in transcription activator activity and transcription. (592 aa) |
| | glgS | Motility and biofilm regulator; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. (66 aa) |
| | yqjA | General envelope maintenance protein; May be a membrane transporter required for proton motive force (PMF)-dependent drug efflux. Required, with YghB, for the proper export of certain periplasmic amidases and, possibly, other Tat substrates. May play a role in determining membrane lipid composition. Belongs to the DedA family. (220 aa) |
| | mzrA | Modulator of EnvZ/OmpR regulon; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. Links the two-component systems CpxA/CpxR and EnvZ/OmpR. Belongs to the MzrA family. (127 aa) |
| | yqjC | DUF1090 family putative periplasmic protein. (122 aa) |
| | yqjD | Membrane-anchored ribosome-binding protein; Upon overexpression inhibits growth. (101 aa) |
| | yqjE | DUF1469 family inner membrane protein. (134 aa) |
| | yqjK | Uncharacterized protein. (99 aa) |
| | yhbS | GNAT family putative N-acetyltransferase; Belongs to the acetyltransferase family. (167 aa) |
| | yhcO | Putative barnase inhibitor; Belongs to the barstar family. (90 aa) |
| | yhdV | Putative outer membrane protein. (73 aa) |
| | fic | Stationary phase-induced protein, putative toxin; Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP. May have some role in cell division. (200 aa) |
| | yhfG | Putative antitoxin for Fic. (55 aa) |
| | yhhA | DUF2756 family protein. (146 aa) |
| | uspB | Protein involved in response to stress and xenobiotic metabolic process. (111 aa) |
| | uspA | Universal stress global response regulator; Required for resistance to DNA-damaging agents; Belongs to the universal stress protein A family. (144 aa) |
| | yiaC | GNAT family putative N-acetyltransferase; N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins. Overexpression inhibits motility. (146 aa) |
| | yiaD | Multicopy suppressor of bamB; Suppresses temperature-sensitive mutations in BamB when overexpressed. (219 aa) |
| | yiaG | HTH_CROC1 family putative transcriptional regulator; Protein involved in regulation of transcription, DNA-dependent. (96 aa) |
| | waaH | LPS(HepIII)-glucuronic acid glycosyltransferase; Putative regulator; Belongs to the glycosyltransferase 2 family. (344 aa) |
| | yiiE | CopG family putative transcriptional regulator; Belongs to the YiiE family. (70 aa) |
| | yiiF | Putative thymol sensitivity protein, CopG family putative transcriptional regulator; To E.coli YiiE. (72 aa) |
| | yiiS | UPF0381 family protein; Belongs to the UPF0381 family. (99 aa) |
| | uspD | Stress-induced protein; Required for resistance to DNA-damaging agents. (142 aa) |
| | yjaB | GNAT-family putative N-acetyltransferase; N-epsilon-lysine acetyltransferase that catalyzes acetylation of a large number of proteins. Binds acetyl-CoA ; Belongs to the acetyltransferase family. (147 aa) |
| | yjbJ | Stress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family. (69 aa) |
| | yjcB | Putative inner membrane protein. (93 aa) |
| | phnP | 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase; Catalyzes the hydrolysis of the cyclic ribose-phosphate to form alpha-D-ribose 1,5-bisphosphate. (252 aa) |
| | phnO | Aminoalkylphosphonate N-acetyltransferase; Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including aminomethylphosphonate, (S)-1-aminoethylphosphonate and 2- aminoethyl- and 3-aminopropylphosphonate, using acetyl-CoA as acetyl donor. Is required for the utilization of aminomethylphosphonate and (S)-1-aminoethylphosphonate as a phosphate source via the C-P lyase pathway. Is also essential for the detoxification of (S)-1- aminoethylphosphonate, a structural analog of D-alanine that has bacteriocidal properties due to inhibitio [...] (144 aa) |
| | phnN | Ribose 1,5-bisphosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor. (185 aa) |
| | phnM | Ribophosphonate triphosphate hydrolase; Catalyzes the hydrolysis of alpha-D-ribose 1- methylphosphonate triphosphate (RPnTP) to form alpha-D-ribose 1- methylphosphonate phosphate (PRPn) and diphosphate. Belongs to the metallo-dependent hydrolases superfamily. (378 aa) |
| | phnL | Ribophosphonate triphosphate synthase subunit; Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate; Belongs to the ABC transporter superfamily. (226 aa) |
| | phnK | Carbon-phosphorus lyase complex subunit, putative ATP transporter ATP-binding protein; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. (252 aa) |
| | phnJ | Carbon-phosphorus lyase, SAM-dependent; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP). (281 aa) |
| | phnI | Ribophosphonate triphosphate synthase complex putative catalytic subunit; Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively. (354 aa) |
| | phnH | Ribophosphonate triphosphate synthase subunit; Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. (194 aa) |
| | phnG | Ribophosphonate triphosphate synthase subunit; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. (150 aa) |
| | phnF | Putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator. (241 aa) |
| | phnD | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. (338 aa) |
| | phnC | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. (262 aa) |
| | yjdN | Metalloprotein superfamily protein. (147 aa) |
| | yjdM | Zinc-ribbon family protein. (111 aa) |
| | yjdI | Putative 4Fe-4S mono-cluster protein. (76 aa) |
| | yjdJ | GNAT family putative N-acetyltransferase. (90 aa) |
| | dtpC | Dipeptide and tripeptide permease; Proton-dependent permease that transports di- and tripeptides. Shows significantly higher specificity towards dipeptides than tripeptides. Has a preference for dipeptides with a C-terminal Lys residue. Can bind Ala-Lys, Lys-Ala, Ala-Ala. Can also transport alanine and trialanine. Belongs to the PTR2/POT transporter (TC 2.A.17) family. (485 aa) |
| | yjeJ | Uncharacterized protein. (289 aa) |
| | yjgM | GNAT family putative N-acetyltransferase; Putative acyltransferase; Belongs to the acetyltransferase family. (167 aa) |
| | rimI | ribosomal-protein-S18-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. Also acts as a N-epsilon-lysine acetyltransferase that catalyzes acetylation of several proteins. (148 aa) |
| | osmY | Salt-inducible putative ABC transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress. (201 aa) |
| | ymdF | KGG family protein; Belongs to the con-10 family. (57 aa) |
| | ytjA | Uncharacterized protein. (53 aa) |
