STRINGSTRING
yahO yahO psiF psiF ybaY ybaY ybaA ybaA ylaC ylaC uspG uspG ybeL ybeL ybgA ybgA phr phr ybgS ybgS ybhL ybhL ybhM ybhM dps dps ybjP ybjP ybjQ ybjQ amiD amiD ybjX ybjX cspD cspD ycaC ycaC ycaD ycaD ycaP ycaP yccJ yccJ wrbA wrbA msyB msyB ycgB ycgB ychH ychH chaB chaB yciE yciE yciF yciF yciG yciG osmB osmB uspE uspE uspF uspF hslJ hslJ ydcK ydcK sra sra bdm bdm osmC osmC ydhB ydhB ydhC ydhC cfa cfa ydhS ydhS osmE osmE yeaG yeaG yeaH yeaH yebV yebV uspC uspC yodD yodD yedP yedP yegP yegP yohC yohC yfcG yfcG ypeC ypeC yphA yphA ygaU ygaU ygaM ygaM ygdI ygdI ygeV ygeV glgS glgS yqjA yqjA mzrA mzrA yqjC yqjC yqjD yqjD yqjE yqjE yqjK yqjK yhcO yhcO yhdV yhdV fic fic yhfG yhfG yhhA yhhA uspB uspB uspA uspA yiaD yiaD yiaG yiaG yiiE yiiE yiiF yiiF yiiS yiiS uspD uspD yjbJ yjbJ yjcB yjcB yjeJ yjeJ osmY osmY ymdF ymdF ytjA ytjA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yahOPeriplasmic protein, function unknown, YhcN family. (91 aa)
psiFPsiF family protein; Induced by phosphate starvation; Protein involved in phosphorus metabolic process and response to starvation. (106 aa)
ybaYOuter membrane lipoprotein; Glycoprotein/polysaccharide metabolism; Protein involved in lipoprotein biosynthetic process and glycoprotein biosynthetic process. (190 aa)
ybaADUF1428 family protein. (117 aa)
ylaCDUF1449 family inner membrane protein. (156 aa)
uspGUniversal stress protein UP12; Has intrinsic autoadenylation and autophosphorylation activities, probably on Ser or Thr residues. Belongs to the universal stress protein A family. (142 aa)
ybeLDUF1451 family protein; Putative alpha helical protein. (160 aa)
ybgADUF1722 family protein. (169 aa)
phrDeoxyribodipyrimidine photolyase, FAD-binding; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. (472 aa)
ybgSPutative homeobox protein. (126 aa)
ybhLPutative acetate transporter; BAX Inhibitor-1 family inner membrane protein. (234 aa)
ybhMBAX Inhibitor-1 family inner membrane protein. (237 aa)
dpsFe-binding and storage protein; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and cop [...] (167 aa)
ybjPPutative lipoprotein. (171 aa)
ybjQUPF0145 family protein. (107 aa)
amiD1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; OM lipoprotein. (276 aa)
ybjXDUF535 family protein; Putative enzyme; To H.influenzae HI_0461. (330 aa)
cspDInhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells. (74 aa)
ycaCPutative isochorismatase family hydrolase; Protein involved in cellular amino acid catabolic process. (208 aa)
ycaDPutative MFS transporter, inner membrane protein. (382 aa)
ycaPUPF0702 family putative inner membrane protein. (230 aa)
yccJUncharacterized protein. (75 aa)
wrbANAD(P)H:quinone oxidoreductase; It seems to function in response to environmental stress when various electron transfer chains are affected or when the environment is highly oxidizing. It reduces quinones to the hydroquinone state to prevent interaction of the semiquinone with O2 and production of superoxide. It prefers NADH over NADPH. (198 aa)
msyBMulticopy suppressor of secY and secA; Could participate in the normal pathway of protein export. (124 aa)
ycgBSpoVR family stationary phase protein; To B.subtilis SpoVR. (510 aa)
ychHDUF2583 family putative inner membrane protein. (92 aa)
chaBCation transport regulator; Might be a regulator of the sodium-potassium/proton antiporter ChaA; Belongs to the ChaB family. (76 aa)
yciEPutative rubrerythrin/ferritin-like metal-binding protein. (168 aa)
yciFPutative structural proteins. (166 aa)
yciGKGG family protein; Belongs to the con-10 family. (59 aa)
osmBOsmotically and stress inducible lipoprotein; Provides resistance to osmotic stress. May be important for stationary-phase survival. (72 aa)
uspEStress-induced protein; Required for resistance to DNA-damaging agents. (316 aa)
uspFUniversal stress protein F; Pseudogene, prophage Rac integration site ttcA duplication;Phage or Prophage Related. (144 aa)
hslJHeat-inducible lipoprotein involved in novobiocin resistance; Heat shock protein hslJ; Protein involved in response to temperature stimulus. (140 aa)
ydcKUncharacterized protein; Putative enzyme; Not classified; Belongs to the transferase hexapeptide repeat family. (326 aa)
sraStationary-phase-induced ribosome-associated protein; Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein. Belongs to the SRA family. (45 aa)
bdmBiofilm-dependent modulation protein. (71 aa)
osmCLipoyl-dependent Cys-based peroxidase, hydroperoxide resistance; Preferentially metabolizes organic hydroperoxides over inorganic hydrogen peroxide; Belongs to the OsmC/Ohr family. (143 aa)
ydhBPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (310 aa)
ydhCPutative arabinose efflux transporter; Putative transport protein. (403 aa)
cfaCyclopropane fatty acyl phospholipid synthase, SAM-dependent; Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge. (382 aa)
ydhSPutative oxidoreductase. (534 aa)
osmEOsmotically-inducible lipoprotein; Activator of ntrL gene; Protein involved in transcription activator activity, transcription and response to osmotic stress. (112 aa)
yeaGProtein kinase, endogenous substrate unidentified; autokinase; Belongs to the PrkA family. (644 aa)
yeaHUPF0229 family protein; Belongs to the UPF0229 family. (427 aa)
yebVUncharacterized protein. (78 aa)
uspCUniversal stress protein; Required for resistance to DNA-damaging agents. (142 aa)
yodDUncharacterized protein. (75 aa)
yedPPutative mannosyl-3-phosphoglycerate phosphatase. (271 aa)
yegPUPF0339 family protein; Belongs to the UPF0339 family. Duplicated subfamily. (110 aa)
yohCYip1 family inner membrane protein. (195 aa)
yfcGGSH-dependent disulfide bond oxidoreductase; Exhibits a very robust glutathione (GSH)-dependent disulfide- bond reductase activity toward the model substrate, 2-hydroxyethyl disulfide; the actual physiological substrates are not known. Has also a low GSH-dependent hydroperoxidase activity toward cumene hydroperoxide, but does not reduce H(2)O(2), tert-butyl hydroperoxide, benzyl peroxide, or lauroyl peroxide. Exhibits little or no GSH transferase activity with most typical electrophilic substrates, and has no detectable transferase activity using glutathionylspermidine (GspSH) as the n [...] (215 aa)
ypeCDUF2502 family putative periplasmic protein; The overlapping reading frame (b2391) is no longer thought to be an actual gene, and has been deaccessioned; To E.coli YaaX. (108 aa)
yphADoxX family inner membrane protein. (140 aa)
ygaUUncharacterized protein; Highly specific potassium binding protein that is required for normal growth in the presence of high levels of external K(+). May act as a sensor of cytoplasmic K(+) concentration. Binds a single K(+) ion, which induces a large conformational change. Can also bind the larger alkali metal ions Rb(+) and Cs(+), and NH(4)(+). May be involved in the regulation of peptidoglycan cross-linking. (149 aa)
ygaMPutative membrane-anchored DUF883 family ribosome-binding protein. (109 aa)
ygdIDUF903 family verified lipoprotein. (75 aa)
ygeVPutative transcriptional regulator; Protein involved in transcription activator activity and transcription. (592 aa)
glgSMotility and biofilm regulator; Major determinant of cell surface composition. Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides. (66 aa)
yqjAGeneral envelope maintenance protein; May be a membrane transporter required for proton motive force (PMF)-dependent drug efflux. Required, with YghB, for the proper export of certain periplasmic amidases and, possibly, other Tat substrates. May play a role in determining membrane lipid composition. Belongs to the DedA family. (220 aa)
mzrAModulator of EnvZ/OmpR regulon; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. Links the two-component systems CpxA/CpxR and EnvZ/OmpR. Belongs to the MzrA family. (127 aa)
yqjCDUF1090 family putative periplasmic protein. (122 aa)
yqjDMembrane-anchored ribosome-binding protein; Upon overexpression inhibits growth. (101 aa)
yqjEDUF1469 family inner membrane protein. (134 aa)
yqjKUncharacterized protein. (99 aa)
yhcOPutative barnase inhibitor; Belongs to the barstar family. (90 aa)
yhdVPutative outer membrane protein. (73 aa)
ficStationary phase-induced protein, putative toxin; Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (By similarity). Involved in cell filamentation induced by cyclic AMP. May have some role in cell division. (200 aa)
yhfGPutative antitoxin for Fic. (55 aa)
yhhADUF2756 family protein. (146 aa)
uspBProtein involved in response to stress and xenobiotic metabolic process. (111 aa)
uspAUniversal stress global response regulator; Required for resistance to DNA-damaging agents; Belongs to the universal stress protein A family. (144 aa)
yiaDMulticopy suppressor of bamB; Suppresses temperature-sensitive mutations in BamB when overexpressed. (219 aa)
yiaGHTH_CROC1 family putative transcriptional regulator; Protein involved in regulation of transcription, DNA-dependent. (96 aa)
yiiECopG family putative transcriptional regulator; Belongs to the YiiE family. (70 aa)
yiiFPutative thymol sensitivity protein, CopG family putative transcriptional regulator; To E.coli YiiE. (72 aa)
yiiSUPF0381 family protein; Belongs to the UPF0381 family. (99 aa)
uspDStress-induced protein; Required for resistance to DNA-damaging agents. (142 aa)
yjbJStress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family. (69 aa)
yjcBPutative inner membrane protein. (93 aa)
yjeJUncharacterized protein. (289 aa)
osmYSalt-inducible putative ABC transporter periplasmic binding protein; Hyperosmotically inducible periplasmic protein; Protein involved in response to osmotic stress. (201 aa)
ymdFKGG family protein; Belongs to the con-10 family. (57 aa)
ytjAUncharacterized protein. (53 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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