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pphA pphA yebY yebY yebZ yebZ yobA yobA yobB yobB exoX exoX alx alx
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pphASerine/threonine-specific protein phosphatase 1; Plays a key role in signaling protein misfolding via the CpxR/CPXA transducing system. It also modulates the phosphorylated status of many phosphoproteins in E.coli, some of which acting as major chaperones. Has been shown, in vitro, to act on Ser, Thr and Tyr- phosphorylated substrates; Belongs to the PPP phosphatase family. PP-1 subfamily. (218 aa)
yebYDUF2511 family protein. (113 aa)
yebZInner membrane protein; Putative resistance protein; Protein involved in response to drug. (290 aa)
yobACopC family protein. (124 aa)
yobBC-N hydrolase family protein. (218 aa)
exoXExodeoxyribonuclease 10; Capable of degrading both single-strand and double-strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. (220 aa)
alxPutative membrane-bound redox modulator; Has been proposed to be a redox modulator. (321 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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