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yahB yahB ybeF ybeF rihA rihA ybhD ybhD ycaN ycaN ydcI ydcI yneJ yneJ dmlR dmlR cbl cbl nac nac lrhA lrhA nupC nupC xapR xapR xapB xapB xapA xapA yfeN yfeN yfeR yfeR yfeH yfeH hcaR hcaR yfhH yfhH lysR lysR ygfI ygfI nupG nupG yhjC yhjC yiaT yiaT yiaU yiaU yihG yihG yijO yijO yjbB yjbB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yahBPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription. (310 aa)
ybeFPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (317 aa)
rihARibonucleoside hydrolase 1; Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively. (311 aa)
ybhDPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (317 aa)
ycaNPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (302 aa)
ydcIPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (307 aa)
yneJPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (293 aa)
dmlRTranscriptional activator of dmlA; Transcriptional regulator required for the aerobic growth on D-malate as the sole carbon source. Induces the expression of dmlA in response to D-malate or L- or meso-tartrate. Negatively regulates its own expression. (307 aa)
cblssuEADCB/tauABCD operon transcriptional activator; May be an accessory regulatory protein within the cys regulon. (316 aa)
nacNitrogen assimilation regulon transcriptional regulator; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression (By similarity). (305 aa)
lrhATranscriptional repressor of flagellar, motility and chemotaxis genes; Not known, does not seem to act on the proton translocating NADH dehydrogenase genes (nuoA-N) which are part of the lrhA operon. (312 aa)
nupCNucleoside (except guanosine) transporter; Transports nucleosides with a high affinity except guanosine and deoxyguanosine. Driven by a proton motive force. Transports cytidine, uridine, thymidine, adenosine and inosine. Can also transport xanthosine, but with a very low affinity. (400 aa)
xapRTranscriptional activator of xapAB; Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine. (294 aa)
xapBXanthosine transporter; Uptake of xanthosine. Driven by a proton motive force. Can also transport other nucleosides such as inosine, adenosine, cytidine, uridine and thymidine. (418 aa)
xapAPurine nucleoside phosphorylase 2; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. This protein can degrade all purine nucleosides including xanthosine, inosine and guanosine, but cannot cleave adenosine, deoxyadenosine or hypoxanthine arabinoside. Has a preference for the neutral over the monoanionic form of xanthosine. (277 aa)
yfeNPutative outer membrane protein; Putative sugar hydrolase; Belongs to the nucleoside-specific channel-forming outer membrane porin (Tsx) (TC 1.B.10) family. (254 aa)
yfeRPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (308 aa)
yfeHPutative inorganic ion transporter; Putative cytochrome oxidase; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (332 aa)
hcaRHca operon transcriptional regulator; Transcriptional activator of the hca operon for 3- phenylpropionic acid catabolism. (296 aa)
yfhHPutative DNA-binding transcriptional regulator. (282 aa)
lysRTranscriptional activator of lysA; This protein activates the transcription of the lysA gene encoding diaminopimelate decarboxylase. LysR is also a negative regulator of its own expression; Belongs to the LysR transcriptional regulatory family. (311 aa)
ygfIPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (298 aa)
nupGNucleoside transporter; Broad-specificity transporter of purine and pyrimidine nucleosides. Driven by a proton motive force. Can transport uridine, adenosine, inosine, guanosine, thymidine and cytidine. Can also transport xanthosine, but with a very low affinity. Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family. (418 aa)
yhjCPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (299 aa)
yiaTPutative outer membrane protein YiaT; Pseudogene, internal sequence remnant. (246 aa)
yiaUPutative transcriptional regulator LYSR-type; Protein involved in transcription activator activity, transcription repressor activity and transcription; Belongs to the LysR transcriptional regulatory family. (324 aa)
yihGInner membrane protein, inner membrane acyltransferase; Putative endonuclease. (310 aa)
yijOPutative ARAC-type regulatory protein; Protein involved in transcription activator activity and transcription. (283 aa)
yjbBPutative alpha helix protein. (543 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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