STRINGSTRING
intF intF intD intD ymfD ymfD ymfE ymfE lit lit intE intE xisE xisE ymfI ymfI ymfJ ymfJ cohE cohE croE croE ymfL ymfL ymfM ymfM ymfR ymfR ymfQ ymfQ stfP stfP tfaP tfaP tfaE tfaE pinE pinE intR intR ydaQ ydaQ ydaC ydaC ralR ralR recT recT recE recE racC racC kilR kilR ydaG ydaG racR racR ydaS ydaS ydaT ydaT ydaU ydaU ydaV ydaV ynaK ynaK dicC dicC dicA dicA ydfA ydfA ydfB ydfB ydfC ydfC dicB dicB ydfD ydfD yegS yegS yfdC yfdC intS intS gtrA gtrA gtrB gtrB gtrS gtrS yfdK yfdK yfdN yfdN yfdP yfdP yfdQ yfdQ yfdR yfdR yfdS yfdS yfdT yfdT intA intA yfjH yfjH alpA alpA yfjI yfjI yfjJ yfjJ ygeI ygeI torI torI ydaE ydaE ydaF ydaF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
intFCP4-6 prophage; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. (466 aa)
intDDLP12 prophage; Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. (387 aa)
ymfDE14 prophage; putative SAM-dependent methyltransferase. (221 aa)
ymfEE14 prophage; putative inner membrane protein. (234 aa)
litT4 phage exclusion protein; Interacts with a short DNA sequence about one-quarter of the way into the major capsid protein gene 23 of T4; general translation inhibition occurs when this late gene of the virus is expressed. Belongs to the peptidase U49 family. (297 aa)
intEE14 prophage; Integrase from the cryptic lambdoic prophage e14. Integrase is necessary for integration of the phage into the host genome by site- specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. (375 aa)
xisEE14 prophage; putative excisionase; To lambdoid phages excisionases. (81 aa)
ymfIE14 prophage; uncharacterized protein. (113 aa)
ymfJE14 prophage; uncharacterized protein. (102 aa)
cohEE14 prophage; repressor protein phage e14. (224 aa)
croEE14 prophage; putative DNA-binding transcriptional regulator. (66 aa)
ymfLE14 prophage; putative DNA-binding transcriptional regulator. (185 aa)
ymfME14 prophage; uncharacterized protein. (112 aa)
ymfRUncharacterized protein YmfR; Pseudogene, phage terminase protein A family, e14 prophage;Phage or Prophage Related. (60 aa)
ymfQUncharacterized protein YmfQ; Pseudogene, e14 prophage;Phage or Prophage Related; To phage Mu protein gp48 and H.influenzae HI_1521. (194 aa)
stfPE14 prophage; uncharacterized protein; To E.coli YfdL and M.jannaschii MJ0347. (209 aa)
tfaPE14 prophage; uncharacterized protein; To E.coli YfdK. (137 aa)
tfaEE14 prophage; putative tail fiber assembly protein. (200 aa)
pinESerine recombinase PinE; This protein catalyzes the inversion of an 1800-bp E.coli DNA fragment, the P region, which can exist in either orientation. The function of the inversion is not yet clear. (184 aa)
intRRac prophage; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome (By similarity). (411 aa)
ydaQRac prophage; Putative lambdoid prophage Rac excisionase. (71 aa)
ydaCDUF1187 family protein, Rac prophage; Helps to maintain the integrity of the chromosome by lowering the steady-state level of double strand breaks. This region of DNA acts as an antitoxin to toxin RalR, a DNase, but it seems to be sRNA RalA that has the antitoxin activity and not this putative protein. Therefore the identity of this as a protein-coding gene has been cast into doubt. (69 aa)
ralRRac prophage; Toxic component of a type I toxin-antitoxin (TA) system. Upon overexpression inhibits growth and reduces colony-forming units in both the presence and absence of the Rac prophage, cells become filamentous. Has deoxyribonuclease activity (probably endonucleolytic), does not digest RNA. Its toxic effects are neutralized by sRNA antitoxin RalA, which is encoded in trans on the opposite DNA strand. Has RAL-like activity. (64 aa)
recTRac prophage; Binds to single-stranded DNA and also promotes the renaturation of complementary single-stranded DNA. Function in recombination. Has a function similar to that of lambda RedB. (269 aa)
recERac prophage; Is involved in the RecE pathway of recombination. Catalyzes the degradation of double-stranded DNA. Acts progressively in a 5' to 3' direction, releasing 5'-phosphomononucleotides. Has a strong preference for linear duplex substrate DNA and appears to be unable to initiate degradation from single-stranded breaks in DNA. (866 aa)
racCRacC protein. (91 aa)
kilRKilling protein, Rac prophage; Causes inhibition of cell division. At high levels of expression, can also abolish the rod shape of the cells. Division inhibition by KilR can be relieved by overexpression of the cell division protein FtsZ. (73 aa)
ydaGRac prophage; uncharacterized protein. (44 aa)
racRRac prophage; Repressor protein for rac prophage. (158 aa)
ydaSRac prophage; putative DNA-binding transcriptional regulator. (98 aa)
ydaTRac prophage; uncharacterized protein. (140 aa)
ydaURac prophage; conserved protein. (285 aa)
ydaVRac prophage; Putative DNA replication factor. (248 aa)
ynaKRac prophage; conserved protein. (87 aa)
dicCRepressor protein of division inhibition gene dicB; This protein is a repressor of division inhibition gene dicB. (76 aa)
dicAQin prophage; This protein is a repressor of division inhibition gene dicB. (135 aa)
ydfAQin prophage; uncharacterized protein; To E.coli YdaF. (51 aa)
ydfBQin prophage; uncharacterized protein. (42 aa)
ydfCUncharacterized protein, Qin prophage. (72 aa)
dicBQin prophage; Involved in cell division inhibition; this function can be repressed by DicA and DicC proteins as well as antitoxin CbeA (yeeU). (62 aa)
ydfDQin prophage; uncharacterized protein. (63 aa)
yegSPhosphatidylglycerol kinase, metal-dependent; In vitro phosphorylates phosphatidylglycerol but not diacylglycerol; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. (299 aa)
yfdCPutative transport protein. (310 aa)
intSCPS-53 (KpLE1) prophage; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. (385 aa)
gtrACPS-53 (KpLE1) prophage; Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity); Belongs to the GtrA family. (120 aa)
gtrBCPS-53 (KpLE1) prophage; Involved in O antigen modification. Catalyzes the transfer of the glucose residue from UDP-glucose to a lipid carrier (By similarity). (306 aa)
gtrSSerotype-specific glucosyl transferase, CPS-53 (KpLE1) prophage; Putative ligase. (443 aa)
yfdKUncharacterized protein YfdK; Pseudogene, CPS-53 (KpLE1) prophage; tail fiber assembly protein fragment;Phage or Prophage Related; To E.coli YmfS. (146 aa)
yfdNUncharacterized protein YfdN; CPS-53 (KpLE1) prophage; putative methyltransferase;Phage or Prophage Related. (164 aa)
yfdPUncharacterized protein YfdP; Pseudogene, CPS-53 (KpLE1) prophage; bacteriophage replication protein O family;Phage or Prophage Related; To phage T4 y06Q. (120 aa)
yfdQCPS-53 (KpLE1) prophage; uncharacterized protein. (274 aa)
yfdRCPS-53 (KpLE1) prophage; conserved protein. (178 aa)
yfdSCPS-53 (KpLE1) prophage; uncharacterized protein; To the N-terminal region of phage HK97/HK620 Gp37/hpaH. (120 aa)
yfdTCPS-53 (KpLE1) prophage; uncharacterized protein. (101 aa)
intACP4-57 prophage; Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Part of the cryptic P4-like prophage CP4-57, it excises the prophage when overexpressed, which also requires integration host factor (encoded by ihfA and ihfB). Overexpression of AlpA leads to excision of the CP4-57 prophage, which inactivates ssrA (the gene upstream of the prophage) that encodes tmRNA which is required to rescue stalled ribosomes in a pro [...] (413 aa)
yfjHCP4-57 prophage; Putative histone. (318 aa)
alpACP4-57 prophage; Positive regulator of the expression of the slpA gene. When overexpressed, leads to suppression of the capsule overproduction and UV sensitivity phenotypes of cells mutant for the Lon ATP-dependent protease. Part of the cryptic P4-like prophage CP4-57. Overexpression of AlpA leads to excision of the CP4-57 prophage by IntA. This inactivates ssrA (the gene upstream of the prophage) that encodes tmRNA which is required to rescue stalled ribosomes in a process known as trans- translation. (70 aa)
yfjICP4-57 prophage; uncharacterized protein. (469 aa)
yfjJCP4-57 prophage; uncharacterized protein; To E.coli YagK. (208 aa)
ygeIUncharacterized protein. (72 aa)
torIResponse regulator inhibitor for tor operon; Transcription inhibitory protein for the torCAD operon. Also acts as an excisionase and plays an essential role in the defective prophage CPS53 excision. (66 aa)
ydaEConserved protein, Rac prophage. (56 aa)
ydaFUncharacterized protein, Rac prophage; To E.coli YdfA. (51 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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