7 items (Escherichia coli K12) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Input:
	dppF	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (334 aa)
	dppD	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. (327 aa)
	ccmA	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. (207 aa)
	nrfE	Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. (552 aa)
	ccmB	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. (220 aa)
	ccmC	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. (245 aa)
	ccmF	Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. (647 aa)

Your Current Organism:

Escherichia coli K12

NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ccmA	ccmB	b2201	b2200	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	0.999
ccmA	ccmC	b2201	b2199	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	0.999
ccmA	ccmF	b2201	b2196	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	0.992
ccmA	dppD	b2201	b3541	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system.	0.560
ccmA	dppF	b2201	b3540	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.	0.566
ccmA	nrfE	b2201	b4074	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	0.798
ccmB	ccmA	b2200	b2201	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	0.999
ccmB	ccmC	b2200	b2199	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	0.999
ccmB	ccmF	b2200	b2196	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	0.993
ccmB	dppD	b2200	b3541	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system.	0.540
ccmB	dppF	b2200	b3540	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.	0.540
ccmB	nrfE	b2200	b4074	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	0.821
ccmC	ccmA	b2199	b2201	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	0.999
ccmC	ccmB	b2199	b2200	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	0.999
ccmC	ccmF	b2199	b2196	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	0.998
ccmC	dppD	b2199	b3541	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system.	0.540
ccmC	dppF	b2199	b3540	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Dipeptide/heme ABC transporter ATPas; Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.	0.540
ccmC	nrfE	b2199	b4074	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	Heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; May be required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	0.829
ccmF	ccmA	b2196	b2201	Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system.	0.992
ccmF	ccmB	b2196	b2200	Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase.	Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.	0.993

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