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| | livG | Branched-chain amino acid ABC transporter ATPase; Component of the leucine-specific transport system. (255 aa) |
| | livM | Branched-chain amino acid ABC transporter permease; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily. (425 aa) |
| | livH | Branched-chain amino acid ABC transporter permease; Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane; Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily. (308 aa) |
| | livK | Leucine transporter subunit; This protein is a component of the leucine-specific transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids in E.coli; Belongs to the leucine-binding protein family. (369 aa) |
| | mdtE | Anaerobic multidrug efflux transporter, ArcA-regulated; Part of the tripartite efflux system MdtEF-TolC, which confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa) |
| | mdtF | Anaerobic multidrug efflux transporter, ArcA-regulated; Part of the tripartite efflux system MdtEF-TolC, which confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1037 aa) |
| | dctA | C4-dicarboxylic acid, orotate and citrate transporter; Responsible for the aerobic transport of the dicarboxylates fumarate, L- and D-malate and to a lesser extent succinate, from the periplasm across the inner membrane; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (428 aa) |
| | yiaM | 2,3-diketo-L-gulonate TRAP transporter small permease protein; Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L- gulonate. (157 aa) |
| | lldP | L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force. (551 aa) |
| | gltS | Glutamate transporter; Catalyzes the sodium-dependent, binding-protein-independent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. (401 aa) |
| | proV | Glycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system (Probable). (400 aa) |
| | alaE | Alanine exporter, alanine-inducible, stress-responsive; Exports L-alanine; Belongs to the AlaE exporter family. (149 aa) |
| | gabP | Gamma-aminobutyrate transporter; Transporter for GABA; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (466 aa) |
| | eamB | Cysteine and O-acetylserine exporter; Exporter of O-acetylserine (OAS) and cysteine. Belongs to the Rht family. (195 aa) |
| | focB | Putative formate transporter; Involved in the bidirectional transport of formate. Belongs to the FNT transporter (TC 2.A.44) family. (282 aa) |
| | acrD | Aminoglycoside/multidrug efflux system; Participates in the efflux of aminoglycosides. Confers resistance to a variety of these substances. Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1037 aa) |
| | emrK | Multidrug resistance efflux pump membrane fusion protein; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. (387 aa) |
| | emrY | Putative multidrug efflux system; Part of the tripartite efflux system EmrYK-TolC, which confers resistance to various drugs. (512 aa) |
| | dsdX | D-serine transporter; A D-serine-specific transporter, may function as a H(+) symporter. (445 aa) |
| | yfdC | Putative transport protein. (310 aa) |
| | fadL | Long-chain fatty acid outer membrane transporter; Involved in translocation of long-chain fatty acids across the outer membrane. It is a receptor for the bacteriophage T2. FadL may form a specific channel; Belongs to the OmpP1/FadL family. (446 aa) |
| | argT | Lysine/arginine/ornithine transporter subunit; Part of an ABC transporter involved in lysine, arginine and ornithine transport. Stimulates ATPase activity of HisP (By similarity). (260 aa) |
| | hisJ | Histidine ABC transporter periplasmic binding protein; Part of the histidine permease ABC transporter. Binds histidine. Interacts with HisQMP and stimulates ATPase activity of HisP, which results in histidine translocation (By similarity). (260 aa) |
| | hisQ | Histidine ABC transporter permease; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity). (228 aa) |
| | hisM | Histidine ABC transporter permease; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Probably responsible for the translocation of the substrate across the membrane. Required to relay the ATPase-inducing signal from the solute-binding protein to HisP (By similarity). (238 aa) |
| | hisP | Histidine ABC transporter ATPase; Part of the histidine permease ABC transporter. Also part of a lysine/arginine/ornithine transporter. Responsible for energy coupling to the transport system (By similarity). (257 aa) |
| | glpT | Sn-glycerol-3-phosphate transporter; Responsible for glycerol-3-phosphate uptake. (452 aa) |
| | bcr | Bicyclomycin/cysteine/sulfonamide efflux transporter; Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance. Probable membrane translocase. A transporter able to export peptides. When overexpressed, allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide overproduction of this protein increases export of the dipeptide. Belongs [...] (396 aa) |
| | lysP | Lysine transporter; Permease that is involved in the transport across the cytoplasmic membrane of lysine; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (489 aa) |
| | mdtC | Multidrug efflux system, subunit C; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function. (1025 aa) |
| | mdtB | Multidrug efflux system, subunit B; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function. (1040 aa) |
| | mdtA | Multidrug efflux system, subunit A; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate. MdtABC requires TolC for its function. Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (415 aa) |
| | yeeO | Putative multdrug exporter, MATE family; A transporter able to export peptides and flavins. When overexpressed allows cells deleted for multiple peptidases (pepA, pepB, pepD and pepN) to grow in the presence of dipeptides Ala-Gln or Gly-Tyr which otherwise inhibit growth. Cells overexpressing this protein have decreased intracellular levels of Ala-Gln dipeptide, and in a system that produces the Ala-Gln dipeptide, overproduction of this protein increases its export. When overexpressed increases secretion of FMN and FAD but not riboflavin; intracellular concentrations of FMN and ribofla [...] (495 aa) |
| | shiA | Shikimate transporter; Pseudogene, glycosyltransferase homology. (438 aa) |
| | fliY | Cystine transporter subunit; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Binds cystine ; Belongs to the bacterial solute-binding protein 3 family. (266 aa) |
| | yecS | ABC family putative inner membrane permease; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Probably responsible for the translocation of the substrate across the membrane (Probable). (222 aa) |
| | yecC | Putative ABC transporter ATPase; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Probably responsible for energy coupling to the transport system (Probable). (250 aa) |
| | leuE | Leucine efflux protein; Exporter of leucine. Can also transport its natural analog L- alpha-amino-n-butyric acid and some other structurally unrelated amino acids. (212 aa) |
| | ydjN | Putative transporter; Involved in L-cystine transport. Can probably also transport L-cysteine. Mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (463 aa) |
| | eamA | Cysteine and O-acetyl-L-serine efflux system; May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L- serine (OAS)), and for other amino acids and their metabolites. Belongs to the EamA transporter family. (299 aa) |
| | ydcO | BenE family inner membrane putative transporter; Putative membrane transport protein. (391 aa) |
| | abgT | P-aminobenzoyl-glutamate transporter; Essential for aminobenzoyl-glutamate utilization. It catalyzes the concentration-dependent uptake of p-aminobenzoyl- glutamate (PABA-GLU) into the cell and allows accumulation of PABA-GLU to a concentration enabling AbgAB to catalyze cleavage into p- aminobenzoate and glutamate. It seems also to increase the sensitivity to low levels of aminobenzoyl-glutamate. May actually serve physiologically as a transporter for some other molecule, perhaps a dipeptide, and that it transports p-aminobenzoyl-glutamate as a secondary activity. The physiological ro [...] (508 aa) |
| | dauA | C4-dicarboxylic acid transporter; Responsible for the aerobic transport of succinate from the periplasm to the cytoplasm at acidic pH. Can transport other C4- dicarboxylic acids such as aspartate and fumarate. May also play a role in the regulation of C4-dicarboxylic acid metabolism at pH 7, via regulation of expression and/or activity of DctA. May act as a co- sensor of DcuS. (559 aa) |
| | putP | Proline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline. This protein is also capable of using lithium as the transport cation. Also catalyzes the uptake of propionate. (502 aa) |
| | ssuA | Aliphatic sulfonate ABC transporter periplasmic binding protein; Part of a binding-protein-dependent transport system for aliphatic sulfonates. Putative binding protein; Belongs to the bacterial solute-binding protein SsuA/TauA family. (319 aa) |
| | ssuC | Aliphatic sulfonate ABC transporter permease; Part of a binding-protein-dependent transport system for aliphatic sulfonates. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (263 aa) |
| | ssuB | Aliphatic sulfonate ABC transporter ATPase; Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system (Probable). (255 aa) |
| | focA | Formate channel; Involved in the bidirectional transport of formate; Belongs to the FNT transporter (TC 2.A.44) family. (285 aa) |
| | cydD | Glutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system. (588 aa) |
| | cydC | Glutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system; Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3.A.1.129.1) family. (573 aa) |
| | ybjE | Putative transporter; Mediates export of lysine; Belongs to the LysO family. (299 aa) |
| | artP | Arginine ABC transporter ATPase; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for energy coupling to the transport system. (242 aa) |
| | artI | Arginine transporter subunit; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. (243 aa) |
| | artQ | Arginine ABC transporter permease; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane. (238 aa) |
| | artM | Arginine ABC transporter permease; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for the translocation of the substrate across the membrane. (222 aa) |
| | artJ | Arginine ABC transporter periplasmic binding protein; Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Binds L-arginine with high affinity. (243 aa) |
| | gsiC | Glutathione ABC transporter permease; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane. (306 aa) |
| | rhtA | Threonine and homoserine efflux system; Involved in the efflux of threonine and homoserine. Can also export other amino acids such as proline, serine, histidine and cysteine; Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family. (295 aa) |
| | glnH | Glutamine transporter subunit; Involved in a glutamine-transport system GlnHPQ. (248 aa) |
| | glnP | Glutamine transporter subunit; Part of the binding-protein-dependent transport system for glutamine; probably responsible for the translocation of the substrate across the membrane. (219 aa) |
| | glnQ | Glutamine transporter subunit; Part of the binding-protein-dependent transport system for glutamine. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. (240 aa) |
| | ybhF | Putative ABC transporter ATPase; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably responsible for energy coupling to the transport system. (578 aa) |
| | ybhS | Putative ABC transporter permease; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family. (377 aa) |
| | ybhR | Putative ABC transporter permease; Part of the ABC transporter complex YbhFSR that could be involved in efflux of cefoperazone. Probably involved in the translocation of the substrate across the membrane. Belongs to the ABC-2 integral membrane protein family. (368 aa) |
| | potE | Putrescine transporter PotE; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. (439 aa) |
| | gltI | Glutamate/aspartate periplasmic binding protein; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Binds to both glutamate and aspartate. (302 aa) |
| | gltJ | Glutamate/aspartate ABC transporter permease; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane. (246 aa) |
| | gltK | Glutamate/aspartate ABC transporter permease; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for the translocation of the substrate across the membrane. (224 aa) |
| | gltL | Glutamate/aspartate ABC transporter ATPase; Part of the ABC transporter complex GltIJKL involved in glutamate and aspartate uptake. Probably responsible for energy coupling to the transport system. (241 aa) |
| | dcuC | Anaerobic C4-dicarboxylate transport; Responsible for the transport of C4-dicarboxylates during anaerobic growth; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. (461 aa) |
| | cstA | Carbon starvation protein involved in peptide utilization; Involved in peptide utilization during carbon starvation. (701 aa) |
| | fepB | Ferrienterobactin ABC transporter periplasmic binding protein; Binds ferrienterobactin; part of the binding-protein- dependent transport system for uptake of ferrienterobactin. (318 aa) |
| | entS | Enterobactin exporter, iron-regulated; Component of an export pathway for enterobactin. Overexpression reduces intracellular arabinose concentrations. (416 aa) |
| | fepD | Ferrienterobactin ABC transporter permease; Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane. (334 aa) |
| | fepG | Iron-enterobactin ABC transporter permease; Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane. (330 aa) |
| | fepC | Ferrienterobactin ABC transporter ATPase; Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for energy coupling to the transport system. (271 aa) |
| | fepE | Regulator of length of O-antigen component of lipopolysaccharide chains; Part of the ferric enterobactin transport system. (377 aa) |
| | fepA | Ferrienterobactin outer membrane transporter; This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D. (746 aa) |
| | acrA | Multidrug efflux system; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with broad substrate specificity that uses the proton motive force to export substrates. This subunit may act as an adapter protein that links AcrB and TolC stably together. It is elongated in shape, being long enough to span the periplasm. (397 aa) |
| | brnQ | Branched-chain amino acid transport system 2 carrier protein; Component of the LIV-II transport system for branched-chain amino acids. This LIV-II transport system may be H(+)-coupled. (439 aa) |
| | tauC | Taurine ABC transporter permease; Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (275 aa) |
| | tauA | Taurine ABC transporter periplasmic binding protein; Part of a binding-protein-dependent transport system for taurine. (320 aa) |
| | metN | DL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. It has also been shown to be involved in formyl-L-methionine transport. Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (343 aa) |
| | metI | DL-methionine transporter subunit; Part of the binding-protein-dependent transport system for D- methionine and the toxic methionine analog alpha-methyl-methionine. Probably responsible for the translocation of the substrate across the membrane. (217 aa) |
| | metQ | DL-methionine transporter subunit; This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system. Belongs to the NlpA lipoprotein family. (271 aa) |
| | aroP | Aromatic amino acid transporter; Permease that is involved in the transport across the cytoplasmic membrane of the aromatic amino acids (phenylalanine, tyrosine, and tryptophan). (457 aa) |
| | satP | Succinate-acetate transporter; Uptake of acetate and succinate. Transport is energetically dependent on the protonmotive force. (188 aa) |
| | yaaJ | Putative transporter; Inner membrane transport protein. (476 aa) |
| | dgoT | D-galactonate transporter; Intake of galactonate into the cell; Belongs to the major facilitator superfamily. Phthalate permease family. (430 aa) |
| | proW | Glycine betaine/proline ABC transporter permease; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa) |
| | proX | Glycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. (330 aa) |
| | ygaZ | Inner membrane protein YgaZ; Pseudogene, major facilitator transporter superfamily;putative transport; Not classified; putative transport protein; Protein involved in response to stress. (245 aa) |
| | ygaH | Putative L-valine exporter, norvaline resistance protein. (111 aa) |
| | ygbN | Putative transport protein. (454 aa) |
| | sdaC | Putative serine transporter; Involved in the import of serine into the cell. May be required for phage C1 adsorption by interacting with DrcB. May also be involved in ampicillin sensitivity. (429 aa) |
| | uacT | Uric acid permease; Proton-dependent high-capacity transporter for uric acid. Shows also a low capacity for transport of xanthine at 37 degrees Celsius but not at 25 degrees Celsius; Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily. (482 aa) |
| | argO | Arginine transporter; Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine. May also be involved in the export of canavanine (a plant-derived antimetabolite). (211 aa) |
| | glcA | Glycolate transporter; Transports glycolate across the membrane. Can also transport L-lactate and D-lactate. Seems to be driven by a proton motive force. (560 aa) |
| | ygiS | Putative ABC transporter permease; Probably part of a deoxycholate transport system. Its expression in the presence of deoxycholate in a ygiS deletion mutant increases intracellular deoxycholate levels and decreases cell growth; higher expression in the presence of deoxycholate inhibits cell growth completely. Bile acid detergents such as deoxycholate are important for host defense against bacterial growth in the gall bladder and duodenum. Belongs to the bacterial solute-binding protein 5 family. (535 aa) |
| | yjiY | Putative transporter; Transports pyruvate with a high affinity and specificity. The process is driven by the proton motive force. Part of a nutrient-sensing regulatory network composed of the two-component regulatory systems BtsS/BtsR and YpdA/YpdB, and their respective target proteins, BtsT and YhjX. Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family. (716 aa) |
| | lgoT | Putative L-galactonate:H+ symporter; Probably responsible for the transport of L-galactonate from the periplasm across the inner membrane. Is essential for growth on L- galactonate as the sole carbon source; Belongs to the major facilitator superfamily. Phthalate permease family. (453 aa) |
| | ytfR | Putative sugar ABC transporter ATPase; Part of the ABC transporter complex YtfQRT-YjfF involved in galactofuranose transport (Probable). Responsible for energy coupling to the transport system (Probable). (500 aa) |
| | gntU | Gluconate transporter, low affinity GNT 1 system; Part of the gluconate utilization system Gnt-I; low-affinity intake of gluconate; Belongs to the GntP permease family. (446 aa) |
| | yjjP | DUF1212 family inner membrane protein; Putative structural protein; To H.influenzae HI_0108. (256 aa) |
| | yjjB | DUF3815 family inner membrane protein. (157 aa) |
| | tolC | Transport channel; Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells. (493 aa) |
| | sstT | Sodium:serine/threonine symporter; Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system). (414 aa) |
| | exuT | Hexuronate transporter; Aldohexuronate transport system. (432 aa) |
| | tdcC | L-threonine/L-serine transporter; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. (443 aa) |
| | mtr | Tryptophan transporter of high affinity; Involved in transporting tryptophan across the cytoplasmic membrane. (414 aa) |
| | nanT | Sialic acid transporter; Catalyzes the proton-dependent transport of sialic acid. Can transport the common sialic acid N-acetylneuraminic acid (Neu5Ac) and the related sialic acids N- glycolylneuraminic acid (Neu5Gc) and 3-keto-3-deoxy-D-glycero-D- galactonononic acid (KDN). Functions as a bidirectional transporter in vitro. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family. (496 aa) |
| | dcuD | Putative transporter; May have a role in the transport of dicarboxylates from the periplasm across the inner membrane. Seems not to be essential for growth. It is likely to be a cryptic gene, as no or low expression has been found under a number of growth conditions and when tested with a large number of potential substrates; Belongs to the DcuC/DcuD transporter (TC 2.A.61) family. (455 aa) |
| | aaeB | P-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell. Substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. (655 aa) |
| | aaeA | P-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeB. (310 aa) |
| | panF | Pantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (483 aa) |
| | nirC | Nitrite transporter; Catalyzes nitrite uptake and nitrite export across the cytoplasmic membrane. Is up to 10-fold more active than NarK or NarU in nitrite uptake for subsequent reduction in the cytoplasm by the NirB/NirD nitrite reductase; Belongs to the FNT transporter (TC 2.A.44) family. (268 aa) |
| | frlA | Putative fructoselysine transporter; Is likely involved in the transport of fructoselysine and psicoselysine to the cytoplasm, where they are degraded. (445 aa) |
| | gntT | Gluconate transporter, high-affinity GNT I system; Part of the gluconate utilization system Gnt-I; high-affinity intake of gluconate. (438 aa) |
| | ugpC | Sn-glycerol-3-phosphate ABC transporter ATPase; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system (Probable). Can also transport glycerophosphoryl diesters. (356 aa) |
| | ugpE | Sn-glycerol-3-phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa) |
| | ugpA | Sn-glycerol-3-phosphate ABC transporter permease; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (295 aa) |
| | ugpB | Sn-glycerol-3-phosphate ABC transporter periplasmic binding protein; sn-glycerol-3-phosphate and glycerophosphoryl diester-binding protein interacts with the binding protein-dependent transport system UgpACE. (438 aa) |
| | livF | Branched-chain amino acid ABC transporter ATPase; Component of the leucine-specific transport system. (237 aa) |
| | rhtC | Threonine efflux pump; Conducts the efflux of threonine. Belongs to the Rht family. (206 aa) |
| | rhtB | Homoserine, homoserine lactone and S-methyl-methionine efflux pump; Conducts the efflux of homoserine and homoserine lactone. Belongs to the Rht family. (206 aa) |
| | kdgT | 2-keto-3-deoxy-D-gluconate transporter; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system; Belongs to the KdgT transporter family. (327 aa) |
| | actP | Acetate transporter; Transports acetate. Also able to transport glycolate. (549 aa) |
| | gltP | Glutamate/aspartate:proton symporter; Catalyzes the proton-dependent, binding-protein-independent transport of glutamate and aspartate. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. GltP subfamily. (437 aa) |
| | adiC | Arginine:agmatine antiporter; Major component of the acid-resistance (AR) system allowing enteric pathogens to survive the acidic environment in the stomach (By similarity). Exchanges extracellular arginine for its intracellular decarboxylation product agmatine (Agm) thereby expelling intracellular protons. (445 aa) |
| | dcuB | C4-dicarboxylate transporter, anaerobic; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (446 aa) |
| | cadB | Putative lysine/cadaverine transporter; Probable cadaverine/lysine antiporter or part of it. (444 aa) |
| | dcuA | C4-dicarboxylate antiporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (433 aa) |
| | yjeH | Putative transporter; Catalyzes the efflux of L-methionine. Can also export L- leucine, L-isoleucine and L-valine. Activity is dependent on electrochemical potential. (418 aa) |
| | ulaA | L-ascorbate-specific enzyme IIC permease component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. Belongs to the UlaA family. (465 aa) |
| | mdtM | Multidrug efflux system protein; Confers resistance to acriflavine, chloramphenicol, norfloxacin, ethidium bromide and TPP; Belongs to the major facilitator superfamily. (410 aa) |
| | gntP | Fructuronate transporter; High-affinity gluconate transporter with fairly broad specificity, including low affinity for glucuronate, several disaccharides, and some hexoses, but not glucose. (447 aa) |
| | nanC | N-acetylnuraminic acid outer membrane channel protein; Outer membrane channel protein allowing the entry of N- acetylneuraminic acid (Neu5Ac, the most abundant sialic acid on host cell surfaces) into the bacteria (Probable). NanC proteins form high- conductance channels which are open at low membrane potentials and which have a weak anion selectivity; Belongs to the oligogalacturonate-specific porin KdgM (TC 1.B.35) family. NanC subfamily. (238 aa) |
| | yjhF | Putative transport system permease. (449 aa) |
| | yjhB | Putative MFS transporter, membrane protein; Putative transport protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (405 aa) |
| | idnT | L-idonate and D-gluconate transporter; Transports L-idonate, D-gluconate and 5-keto-D-gluconate, from the periplasm across the inner membrane. (439 aa) |
| | cycA | D-alanine/D-serine/glycine transporter; Permease that is involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (470 aa) |
| | ulaC | L-ascorbate-specific enzyme IIA component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (154 aa) |
| | ulaB | L-ascorbate-specific enzyme IIB component of PTS; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport. (101 aa) |
