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cydC cydC gsiC gsiC emrE emrE mmuP mmuP caiT caiT yehW yehW yehX yehX yehY yehY osmF osmF proV proV proW proW proX proX panF panF proP proP yecC yecC ydjN ydjN yecS yecS fliY fliY mdtJ mdtJ mdtI mdtI abgT abgT cydD cydD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
cydCGlutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system; Belongs to the ABC transporter superfamily. Cysteine exporter (TC 3.A.1.129.1) family. (573 aa)
gsiCGlutathione ABC transporter permease; Part of the ABC transporter complex GsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane. (306 aa)
emrEDLP12 prophage; Multidrug transporter that expels positively charged hydrophobic drugs across the inner membrane of E.coli., thereby conferring resistance to a wide range of toxic compounds. The drug efflux is coupled to an influx of protons. Is involved in the resistance of E.coli cells to methyl viologen, ethidium bromide and acriflavine. Is also able to transport tetraphenylphosphonium (TPP(+)) and benzalkonium. Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. (110 aa)
mmuPCP4-6 prophage; Transporter for the intake of S-methylmethionine; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (467 aa)
caiTPutative transporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. (504 aa)
yehWPutative ABC transporter permease; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (243 aa)
yehXPutative ABC transporter ATPase; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for energy coupling to the transport system. (308 aa)
yehYPutative ABC transporter permease; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Probably responsible for the translocation of the substrate across the membrane. (385 aa)
osmFPutative ABC transporter periplasmic binding protein; Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Binds glycine betaine with low affinity. Belongs to the OsmX family. (305 aa)
proVGlycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for energy coupling to the transport system (Probable). (400 aa)
proWGlycine betaine/proline ABC transporter permease; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (354 aa)
proXGlycine betaine/proline ABC transporter periplasmic binding protein; Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake. Binds glycine betaine and proline betaine with high affinity. (330 aa)
panFPantothenate:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular pantothenate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (483 aa)
proPProline/glycine betaine transporter; Proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response; Belongs to the major facilitator superfamily. Metabolite:H+ Symporter (MHS) family (TC 2.A.1.6) family. (500 aa)
yecCPutative ABC transporter ATPase; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Probably responsible for energy coupling to the transport system (Probable). (250 aa)
ydjNPutative transporter; Involved in L-cystine transport. Can probably also transport L-cysteine. Mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (463 aa)
yecSABC family putative inner membrane permease; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Probably responsible for the translocation of the substrate across the membrane (Probable). (222 aa)
fliYCystine transporter subunit; Part of the ABC transporter complex FliY-YecC-YecS involved in L-cystine transport. The system can probably also transport L- cysteine, and it mediates accumulation of the toxic compounds L- selenaproline (SCA) and L-selenocystine (SeCys). Binds cystine ; Belongs to the bacterial solute-binding protein 3 family. (266 aa)
mdtJMultidrug efflux system transporter; Catalyzes the excretion of spermidine. Can also confer resistance to deoxycholate and SDS; Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily. (121 aa)
mdtIMultidrug efflux system transporter; Catalyzes the excretion of spermidine. Can also confer resistance to deoxycholate and SDS; Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily. (109 aa)
abgTP-aminobenzoyl-glutamate transporter; Essential for aminobenzoyl-glutamate utilization. It catalyzes the concentration-dependent uptake of p-aminobenzoyl- glutamate (PABA-GLU) into the cell and allows accumulation of PABA-GLU to a concentration enabling AbgAB to catalyze cleavage into p- aminobenzoate and glutamate. It seems also to increase the sensitivity to low levels of aminobenzoyl-glutamate. May actually serve physiologically as a transporter for some other molecule, perhaps a dipeptide, and that it transports p-aminobenzoyl-glutamate as a secondary activity. The physiological ro [...] (508 aa)
cydDGlutathione/cysteine ABC transporter export permease/ATPase; Somehow involved in the cytochrome D branch of aerobic respiration. Seems to be a component of a transport system. (588 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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