STRINGSTRING
ascG ascG galR galR ebgR ebgR xylR xylR treR treR idnR idnR rbsR rbsR cytR cytR lacI lacI purR purR galS galS
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ascGAsc operon transcriptional repressor; Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. (336 aa)
galRGalactose-inducible d-galactose regulon transcriptional repressor; Repressor of the galactose operon. Binds galactose as an inducer. (343 aa)
ebgRTranscriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. (327 aa)
xylRXylose divergent operon transcriptional activator; Regulatory protein for the xylBAFGHR operon. (392 aa)
treRTrehalose 6-phosphate-inducible trehalose regulon transcriptional repressor; Repressor of the treBC operon. It is able to bind trehalose- 6-phosphate and trehalose. (315 aa)
idnRTranscriptional repressor, 5-gluconate-binding; Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate. (332 aa)
rbsRTranscriptional repressor of ribose metabolism; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon. (330 aa)
cytRAnti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. (341 aa)
lacILactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. (360 aa)
purRTranscriptional repressor, hypoxanthine-binding; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. In addition, it participates in the regulation or coregulation of genes involved in de novo pyrimidine nucleotide biosynthesis, salvage and uptake (pyrC, pyrD, carAB and codBA), and of several genes encoding enzymes necessary for nucleotide and polyamine biosynthesis (prsA, glyA, gcvTHP, speA, glnB). Binds to a 16-bp palindromic sequence located within the promoter region [...] (341 aa)
galSGalactose- and fucose-inducible galactose regulon transcriptional isorepressor; Repressor of the mgl operon. Binds galactose and D-fucose as inducers. GalS binds to an operator DNA sequence within its own coding sequence (corresponding to residues 15 to 20). (346 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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