35 items (Escherichia coli K12) - STRING interaction network

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Your Input:
	phnM	Ribophosphonate triphosphate hydrolase; Catalyzes the hydrolysis of alpha-D-ribose 1- methylphosphonate triphosphate (RPnTP) to form alpha-D-ribose 1- methylphosphonate phosphate (PRPn) and diphosphate. Belongs to the metallo-dependent hydrolases superfamily. (378 aa)
	phnL	Ribophosphonate triphosphate synthase subunit; Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate; Belongs to the ABC transporter superfamily. (226 aa)
	phnK	Carbon-phosphorus lyase complex subunit, putative ATP transporter ATP-binding protein; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction. (252 aa)
	phnJ	Carbon-phosphorus lyase, SAM-dependent; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP). (281 aa)
	phnI	Ribophosphonate triphosphate synthase complex putative catalytic subunit; Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively. (354 aa)
	phnH	Ribophosphonate triphosphate synthase subunit; Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. (194 aa)
	phnG	Ribophosphonate triphosphate synthase subunit; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. (150 aa)
	phnF	Putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator. (241 aa)
	phnD	Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. (338 aa)
	phnC	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. (262 aa)
	yjiC	Uncharacterized protein; To E.coli YjfZ. (276 aa)
	yjiM	Putative 2-hydroxyglutaryl-CoA dehydratase; Belongs to the FldB/FldC dehydratase alpha/beta subunit family. (383 aa)
	yjiN	Zinc-type alcohol dehydrogenase-like protein. (426 aa)
	ymgI	Uncharacterized protein. (57 aa)
	yciZ	Uncharacterized protein. (57 aa)
	yjbT	Putative periplasmic protein; Belongs to the YjbT family. (92 aa)
	yjdN	Metalloprotein superfamily protein. (147 aa)
	apaG	Protein associated with Co2+ and Mg2+ efflux. (125 aa)
	yadL	Putative fimbrial-like adhesin protein; Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. (201 aa)
	ynbE	Lipoprotein. (61 aa)
	ydcA	Putative periplasmic protein. (57 aa)
	ydcY	DUF2526 family protein. (77 aa)
	ydcD	Uncharacterized protein YdcD; Pseudogene, Rhs family. (160 aa)
	ydgC	GlpM family inner membrane protein. (111 aa)
	dsrB	Uncharacterized protein. (62 aa)
	yfjK	Radiation resistance protein; DEAD/H helicase-like protein; CP4-57 putative defective prophage. (729 aa)
	yfjL	CP4-57 putative defective prophage, DUF4297/DUF1837 polymorphic toxin family protein. (538 aa)
	crp	cAMP-activated global transcription factor, mediator of catabolite repression; A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site [...] (210 aa)
	yhhQ	DUF165 family inner membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. Transports 7-cyano-7-deazaguanine (preQ(0)) and 7-aminomethyl-7-deazaguanine (preQ(1)), with a preference for preQ(0). (221 aa)
	yicR	UPF0758 family protein; DNA repair protein; Protein involved in DNA-dependent DNA replication and DNA repair; Belongs to the UPF0758 family. YicR subfamily. (222 aa)
	atpC	F1 sector of membrane-bound ATP synthase, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the ATPase epsilon chain family. (139 aa)
	yiiX	Putative lipid binding hydrolase, DUF830 family protein; To E.coli YebB. (202 aa)
	phnP	5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase; Catalyzes the hydrolysis of the cyclic ribose-phosphate to form alpha-D-ribose 1,5-bisphosphate. (252 aa)
	phnO	Aminoalkylphosphonate N-acetyltransferase; Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including aminomethylphosphonate, (S)-1-aminoethylphosphonate and 2- aminoethyl- and 3-aminopropylphosphonate, using acetyl-CoA as acetyl donor. Is required for the utilization of aminomethylphosphonate and (S)-1-aminoethylphosphonate as a phosphate source via the C-P lyase pathway. Is also essential for the detoxification of (S)-1- aminoethylphosphonate, a structural analog of D-alanine that has bacteriocidal properties due to inhibitio [...] (144 aa)
	phnN	Ribose 1,5-bisphosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor. (185 aa)

Your Current Organism:

Escherichia coli K12

NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apaG	yciZ	b0050	b4596	Protein associated with Co2+ and Mg2+ efflux.	Uncharacterized protein.	0.517
apaG	ydcD	b0050	b1457	Protein associated with Co2+ and Mg2+ efflux.	Uncharacterized protein YdcD; Pseudogene, Rhs family.	0.506
apaG	yjbT	b0050	b4620	Protein associated with Co2+ and Mg2+ efflux.	Putative periplasmic protein; Belongs to the YjbT family.	0.541
apaG	yjiM	b0050	b4335	Protein associated with Co2+ and Mg2+ efflux.	Putative 2-hydroxyglutaryl-CoA dehydratase; Belongs to the FldB/FldC dehydratase alpha/beta subunit family.	0.529
apaG	ymgI	b0050	b4593	Protein associated with Co2+ and Mg2+ efflux.	Uncharacterized protein.	0.452
dsrB	yciZ	b1952	b4596	Uncharacterized protein.	Uncharacterized protein.	0.803
dsrB	ydcA	b1952	b1419	Uncharacterized protein.	Putative periplasmic protein.	0.456
dsrB	ydcY	b1952	b1446	Uncharacterized protein.	DUF2526 family protein.	0.645
dsrB	ydgC	b1952	b1607	Uncharacterized protein.	GlpM family inner membrane protein.	0.457
dsrB	yjbT	b1952	b4620	Uncharacterized protein.	Putative periplasmic protein; Belongs to the YjbT family.	0.601
dsrB	yjiM	b1952	b4335	Uncharacterized protein.	Putative 2-hydroxyglutaryl-CoA dehydratase; Belongs to the FldB/FldC dehydratase alpha/beta subunit family.	0.599
dsrB	ymgI	b1952	b4593	Uncharacterized protein.	Uncharacterized protein.	0.477
phnC	phnD	b4106	b4105	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate.	0.999
phnC	phnF	b4106	b4102	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator.	0.993
phnC	phnG	b4106	b4101	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Ribophosphonate triphosphate synthase subunit; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.	0.997
phnC	phnH	b4106	b4100	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Ribophosphonate triphosphate synthase subunit; Together with PhnG, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate.	0.998
phnC	phnI	b4106	b4099	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Ribophosphonate triphosphate synthase complex putative catalytic subunit; Together with PhnG, PhnH and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. PhnI alone has nucleosidase activity, catalyzing the hydrolysis of ATP or GTP forming alpha-D-ribose 5-triphosphate and adenine or guanine, respectively.	0.995
phnC	phnJ	b4106	b4098	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Carbon-phosphorus lyase, SAM-dependent; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP).	0.996
phnC	phnK	b4106	b4097	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Carbon-phosphorus lyase complex subunit, putative ATP transporter ATP-binding protein; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. PhnK is not required for the ribophosphonate triphosphate (RPnTP) synthase reaction.	0.901
phnC	phnL	b4106	b4096	Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system.	Ribophosphonate triphosphate synthase subunit; Together with PhnG, PhnH and PhnI is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate; Belongs to the ABC transporter superfamily.	0.949

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