STRINGSTRING
insD1-4 insD1-4 insI1 insI1 insE1 insE1 insC1 insC1 insD1 insD1 insE1-2 insE1-2 insE1-3 insE1-3 efeB efeB phoH phoH pgaD pgaD pgaA pgaA insE1-4 insE1-4 ycdU ycdU ghrA ghrA ydbH ydbH ynbE ynbE ydbL ydbL feaR feaR feaB feaB tynA tynA paaA paaA paaK paaK insD1-2 insD1-2 insC1-2 insC1-2 insI1-2 insI1-2 ynbC ynbC ynbD ynbD insD1-3 insD1-3 insC1-3 insC1-3 insE1-5 insE1-5 insC1-4 insC1-4 insC1-5 insC1-5 insD1-5 insD1-5 insC1-6 insC1-6 insD1-6 insD1-6 insI1-3 insI1-3 fecA fecA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
insD1-4Pseudogene, orgA family, part of T3SS PAI ETT2 remnant. (301 aa)
insI1Transposase InsI for insertion sequence element IS30A; Required for the transposition of the insertion element. (383 aa)
insE1Transposase InsE for insertion sequence IS3A; Involved in the transposition of the insertion sequence IS3. (99 aa)
insC1Transposase InsC for insertion element IS2-10; Involved in the transposition of the insertion sequence IS2. (121 aa)
insD1IS2 transposase TnpB; Involved in the transposition of the insertion sequence IS2. (301 aa)
insE1-2IS3 transposase A. (99 aa)
insE1-3Pseudogene, DLP12 prophage;Phage or Prophage Related. (99 aa)
efeBDeferrrochelatase, periplasmic; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Also displays peroxidase activity on guaiacol in vitro. (423 aa)
phoHPhoB-dependent, ATP-binding pho regulon component; may be helicase; induced by P starvation; Protein involved in phosphorus metabolic process and response to starvation; Belongs to the PhoH family. (354 aa)
pgaDBiofilm PGA synthase PgaCD, regulatory subunit; Required for the synthesis of poly-beta-1,6-N-acetyl-D- glucosamine (PGA), a biofilm adhesin polysaccharide. May assist the glycosyltransferase PgaC in the polymerization of PGA. (137 aa)
pgaABiofilm adhesin polysaccharide PGA secretin; Exports the biofilm adhesin polysaccharide poly-beta-1,6-N- acetyl-D-glucosamine (PGA) across the outer membrane. The PGA transported seems to be partially N-deacetylated since N-deacetylation of PGA by PgaB is needed for PGA export through the PgaA porin. (807 aa)
insE1-4IS3 transposase A. (99 aa)
ycdUUncharacterized protein YcdU; Pseudogene. (328 aa)
ghrAGlyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low. (312 aa)
ydbHPutative membrane-anchored protein, function unknown. (879 aa)
ynbELipoprotein. (61 aa)
ydbLDUF1318 family protein. (108 aa)
feaRTranscriptional activator for tynA and feaB; Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism. (301 aa)
feaBPhenylacetaldehyde dehydrogenase; Acts almost equally well on phenylacetaldehyde, 4- hydroxyphenylacetaldehyde and 3,4-dihydroxyphenylacetaldehyde. (499 aa)
tynATyramine oxidase, copper-requiring; The enzyme prefers aromatic over aliphatic amines; Belongs to the copper/topaquinone oxidase family. (757 aa)
paaARing 1,2-phenylacetyl-CoA epoxidase subunit; Component of 1,2-phenylacetyl-CoA epoxidase multicomponent enzyme system which catalyzes the reduction of phenylacetyl-CoA (PA- CoA) to form 1,2-epoxyphenylacetyl-CoA. The subunit A is the catalytic subunit involved in the incorporation of one atom of molecular oxygen into phenylacetyl-CoA. (309 aa)
paaKphenylacetyl-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (437 aa)
insD1-2Pseudogene, autotransporter homolog; interrupted by IS2 and IS30. (301 aa)
insC1-2IS2 repressor TnpA. (121 aa)
insI1-2IS30 transposase; Required for the transposition of the insertion element. (383 aa)
ynbCPutative esterase. (585 aa)
ynbDPutative phosphatase inner membrane protein; Putative enzymes; Belongs to the protein-tyrosine phosphatase family. (430 aa)
insD1-3CP4-44 prophage; putative disrupted hemin or colicin receptor;Phage or Prophage Related; interrupted by IS2 and C-terminal deletion. (301 aa)
insC1-3IS2 repressor TnpA. (121 aa)
insE1-5Pseudogene, repressor for gat operon; interrupted by IS3; split galactitol utilization operon repressor, fragment 2; split galactitol utilization operon repressor, interrupted. (99 aa)
insC1-4IS2 repressor TnpA. (121 aa)
insC1-5Pseudogene; fimbrial export usher family;putative membrane; Not classified; putative membrane protein. (121 aa)
insD1-5IS2 transposase TnpB. (301 aa)
insC1-6Pseudogene, integrase homology;IS, phage, Tn; Phage-related functions and prophages; KpLE2 phage-like element; P4-like integrase. (121 aa)
insD1-6IS2 transposase TnpB. (301 aa)
insI1-3Pseudogene, IS911 transposase B;IS, phage, Tn; Transposon-related functions; extrachromosomal; transposon related. (383 aa)
fecATonB-dependent outer membrane ferric citrate transporter and signal transducer; FecA is the outer membrane receptor protein in the Fe(3+) dicitrate transport system. (774 aa)
Your Current Organism:
Escherichia coli K12
NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655
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