19 items (Escherichia coli K12) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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protein homology

Your Input:
	bhsA	Biofilm, cell surface and signaling protein; Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction; Belongs to the BhsA/McbA family. (85 aa)
	yciG	KGG family protein; Belongs to the con-10 family. (59 aa)
	ynaE	Cold shock protein, Rac prophage. (77 aa)
	ydfK	Cold shock protein YdfK; Cryptic prophage Qin/Kim. (77 aa)
	cspI	Qin prophage; Cold shock-like protein. (70 aa)
	cspB	Qin prophage; cold shock protein. (71 aa)
	cspF	Qin prophage; cold shock protein. (70 aa)
	cspC	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. (69 aa)
	cspA	RNA chaperone and antiterminator, cold-inducible; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'. (70 aa)
	ppiC	Peptidyl-prolyl cis-trans isomerase C (rotamase C); PPIases accelerate the folding of proteins. It prefers amino acid residues with hydrophobic side chains like leucine and phenylalanine in the P1 position of the peptides substrates; Belongs to the PpiC/parvulin rotamase family. (93 aa)
	yjbJ	Stress-induced protein, UPF0337 family; Belongs to the UPF0337 (CsbD) family. (69 aa)
	ymdF	KGG family protein; Belongs to the con-10 family. (57 aa)
	cspG	Homolog of Salmonella cold shock protein; Protein involved in response to temperature stimulus. (70 aa)
	cspH	Stress protein, member of the CspA-family; Cold shock-like protein; Protein involved in response to temperature stimulus. (70 aa)
	cspD	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells. (74 aa)
	ybgS	Putative homeobox protein. (126 aa)
	cspE	Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus. (69 aa)
	hupB	HU, DNA-binding transcriptional regulator, beta subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
	yahO	Periplasmic protein, function unknown, YhcN family. (91 aa)

Your Current Organism:

Escherichia coli K12

NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cspA	cspB	b3556	b1557	RNA chaperone and antiterminator, cold-inducible; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'.	Qin prophage; cold shock protein.	0.611
cspA	cspC	b3556	b1823	RNA chaperone and antiterminator, cold-inducible; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'.	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	0.768
cspA	cspG	b3556	b0990	RNA chaperone and antiterminator, cold-inducible; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'.	Homolog of Salmonella cold shock protein; Protein involved in response to temperature stimulus.	0.659
cspB	cspA	b1557	b3556	Qin prophage; cold shock protein.	RNA chaperone and antiterminator, cold-inducible; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'.	0.611
cspB	cspF	b1557	b1558	Qin prophage; cold shock protein.	Qin prophage; cold shock protein.	0.803
cspB	cspG	b1557	b0990	Qin prophage; cold shock protein.	Homolog of Salmonella cold shock protein; Protein involved in response to temperature stimulus.	0.887
cspB	cspI	b1557	b1552	Qin prophage; cold shock protein.	Qin prophage; Cold shock-like protein.	0.762
cspB	ynaE	b1557	b1375	Qin prophage; cold shock protein.	Cold shock protein, Rac prophage.	0.777
cspC	cspA	b1823	b3556	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	RNA chaperone and antiterminator, cold-inducible; Binds to and stimulates the transcription of the CCAAT- containing, cold-shock-inducible promoters of the H-NS and GyrA proteins. Binds also to the inverted repeat 5'-ATTGG-3'.	0.768
cspC	cspD	b1823	b0880	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	0.482
cspC	cspE	b1823	b0623	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	0.627
cspD	cspC	b0880	b1823	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	0.482
cspD	cspE	b0880	b0623	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	0.561
cspD	cspF	b0880	b1558	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	Qin prophage; cold shock protein.	0.644
cspD	yahO	b0880	b0329	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	Periplasmic protein, function unknown, YhcN family.	0.456
cspE	cspC	b0623	b1823	Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	Stress protein, member of the CspA-family; Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	0.627
cspE	cspD	b0623	b0880	Cold shock protein; Protein involved in transcription activator activity, transcription and response to temperature stimulus.	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	0.561
cspF	cspB	b1558	b1557	Qin prophage; cold shock protein.	Qin prophage; cold shock protein.	0.803
cspF	cspD	b1558	b0880	Qin prophage; cold shock protein.	Inhibitor of DNA replication, cold shock protein homolog; Inhibits DNA replication at both initiation and elongation steps, most probably by binding to the opened, single-stranded regions at replication forks. Plays a regulatory role in chromosomal replication in nutrient-depleted cells.	0.644
cspF	cspH	b1558	b0989	Qin prophage; cold shock protein.	Stress protein, member of the CspA-family; Cold shock-like protein; Protein involved in response to temperature stimulus.	0.685

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