node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
phnC | phnD | b4106 | b4105 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | 0.999 |
phnC | phnF | b4106 | b4102 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator. | 0.993 |
phnC | phnG | b4106 | b4101 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Ribophosphonate triphosphate synthase subunit; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. | 0.997 |
phnC | phnJ | b4106 | b4098 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Carbon-phosphorus lyase, SAM-dependent; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP). | 0.996 |
phnC | phnN | b4106 | b4094 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Ribose 1,5-bisphosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor. | 0.988 |
phnC | phnO | b4106 | b4093 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Aminoalkylphosphonate N-acetyltransferase; Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including aminomethylphosphonate, (S)-1-aminoethylphosphonate and 2- aminoethyl- and 3-aminopropylphosphonate, using acetyl-CoA as acetyl donor. Is required for the utilization of aminomethylphosphonate and (S)-1-aminoethylphosphonate as a phosphate source via the C-P lyase pathway. Is also essential for the detoxification of (S)-1- aminoethylphosphonate, a structural analog of D-alanine that has bacteriocidal properties due to inhibitio [...] | 0.902 |
phnC | phnP | b4106 | b4092 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase; Catalyzes the hydrolysis of the cyclic ribose-phosphate to form alpha-D-ribose 1,5-bisphosphate. | 0.950 |
phnC | phoA | b4106 | b0383 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Alkaline phosphatase; start codon corrected; Protein involved in phosphorus metabolic process; Belongs to the alkaline phosphatase family. | 0.818 |
phnC | pitB | b4106 | b2987 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Phosphate transporter; Low-affinity inorganic phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily. | 0.415 |
phnC | pstS | b4106 | b3728 | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | Phosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.654 |
phnD | phnC | b4105 | b4106 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Phosphonate ABC transporter ATPase; Part of the ABC transporter complex PhnCDE involved in phosphonates, phosphate esters, phosphite and phosphate import. Responsible for energy coupling to the transport system. | 0.999 |
phnD | phnF | b4105 | b4102 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Putative DNA-binding transcriptional regulator of phosphonate uptake and biodegradation; Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator. | 0.993 |
phnD | phnG | b4105 | b4101 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Ribophosphonate triphosphate synthase subunit; Together with PhnH, PhnI and PhnL is required for the transfer of the ribose triphosphate moiety from ATP to methyl phosphonate. | 0.995 |
phnD | phnJ | b4105 | b4098 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Carbon-phosphorus lyase, SAM-dependent; Catalyzes the breakage of the C-P bond in alpha-D-ribose 1- methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP). | 0.998 |
phnD | phnN | b4105 | b4094 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Ribose 1,5-bisphosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). Accepts ATP but not GTP as a phosphoryl donor, and uses ribose 1,5-bisphosphate but not ribose, ribose 1-phosphate, or ribose 5-phosphate as a phosphoryl acceptor. | 0.989 |
phnD | phnO | b4105 | b4093 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Aminoalkylphosphonate N-acetyltransferase; Aminoalkylphosphonate N-acetyltransferase which is able to acetylate a range of aminoalkylphosphonic acids, including aminomethylphosphonate, (S)-1-aminoethylphosphonate and 2- aminoethyl- and 3-aminopropylphosphonate, using acetyl-CoA as acetyl donor. Is required for the utilization of aminomethylphosphonate and (S)-1-aminoethylphosphonate as a phosphate source via the C-P lyase pathway. Is also essential for the detoxification of (S)-1- aminoethylphosphonate, a structural analog of D-alanine that has bacteriocidal properties due to inhibitio [...] | 0.889 |
phnD | phnP | b4105 | b4092 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase; Catalyzes the hydrolysis of the cyclic ribose-phosphate to form alpha-D-ribose 1,5-bisphosphate. | 0.950 |
phnD | phoA | b4105 | b0383 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Alkaline phosphatase; start codon corrected; Protein involved in phosphorus metabolic process; Belongs to the alkaline phosphatase family. | 0.737 |
phnD | pitB | b4105 | b2987 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Phosphate transporter; Low-affinity inorganic phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily. | 0.464 |
phnD | pstS | b4105 | b3728 | Phosphonates-binding periplasmic protein; Phosphonate binding protein that is part of the phosphonate uptake system. Exhibits high affinity for 2-aminoethylphosphonate, and somewhat less affinity to ethylphosphonate, methylphosphonate, phosphonoacetate and phenylphosphonate. | Phosphate ABC transporter periplasmic binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.871 |