node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gor | gshA | b3500 | b2688 | Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Glutamate-cysteine ligase; Protein involved in glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.885 |
gor | gshB | b3500 | b2947 | Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Protein involved in glutathione biosynthetic process. | 0.985 |
gor | lpd | b3500 | b0116 | Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | Dihydrolipoyl dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. | 0.425 |
gshA | gor | b2688 | b3500 | Glutamate-cysteine ligase; Protein involved in glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.885 |
gshA | gshB | b2688 | b2947 | Glutamate-cysteine ligase; Protein involved in glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | Protein involved in glutathione biosynthetic process. | 0.995 |
gshB | gor | b2947 | b3500 | Protein involved in glutathione biosynthetic process. | Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.985 |
gshB | gshA | b2947 | b2688 | Protein involved in glutathione biosynthetic process. | Glutamate-cysteine ligase; Protein involved in glutathione biosynthetic process; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. | 0.995 |
lpd | gor | b0116 | b3500 | Dihydrolipoyl dehydrogenase; Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. | Glutathione oxidoreductase; Maintains high levels of reduced glutathione in the cytosol; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.425 |
nrdA | nrdB | b2234 | b2235 | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.999 |
nrdA | nrdD | b2234 | b4238 | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | Anaerobic ribonucleoside-triphosphate reductase; Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. Belongs to the anaerobic ribonucleoside-triphosphate reductase family. | 0.911 |
nrdA | nrdE | b2234 | b2675 | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1E contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide; Belongs to the ribonucleoside diphosphate reductase large chain family. | 0.931 |
nrdA | nrdF | b2234 | b2676 | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2F contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.998 |
nrdA | nrdH | b2234 | b2673 | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | Hydrogen donor for NrdEF electron transport system; Electron transport system for the ribonucleotide reductase system NrdEF; Belongs to the glutaredoxin family. | 0.759 |
nrdA | nrdI | b2234 | b2674 | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | NrdEF cluster assembly flavodoxin; Probably involved in ribonucleotide reductase function. Belongs to the NrdI family. | 0.792 |
nrdB | nrdA | b2235 | b2234 | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase 1, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. | 0.999 |
nrdB | nrdD | b2235 | b4238 | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | Anaerobic ribonucleoside-triphosphate reductase; Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. Belongs to the anaerobic ribonucleoside-triphosphate reductase family. | 0.926 |
nrdB | nrdE | b2235 | b2675 | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1E contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide; Belongs to the ribonucleoside diphosphate reductase large chain family. | 0.997 |
nrdB | nrdF | b2235 | b2676 | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | Ribonucleoside-diphosphate reductase 2, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2F contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.938 |
nrdB | nrdH | b2235 | b2673 | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | Hydrogen donor for NrdEF electron transport system; Electron transport system for the ribonucleotide reductase system NrdEF; Belongs to the glutaredoxin family. | 0.669 |
nrdB | nrdI | b2235 | b2674 | Ribonucleoside-diphosphate reductase 1, beta subunit, ferritin-like protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis; Belongs to the ribonucleoside diphosphate reductase small chain family. | NrdEF cluster assembly flavodoxin; Probably involved in ribonucleotide reductase function. Belongs to the NrdI family. | 0.965 |