node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
araA | araB | b0062 | b0063 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | 0.999 |
araA | araD | b0062 | b0061 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.999 |
araA | araE | b0062 | b2841 | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.936 |
araB | araA | b0063 | b0062 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.999 |
araB | araD | b0063 | b0061 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.999 |
araB | araE | b0063 | b2841 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.958 |
araB | lacI | b0063 | b0345 | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. | 0.562 |
araD | araA | b0061 | b0062 | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.999 |
araD | araB | b0061 | b0063 | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | 0.999 |
araD | araE | b0061 | b2841 | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.935 |
araD | uidA | b0061 | b1617 | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | beta-D-glucuronidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. | 0.809 |
araE | araA | b2841 | b0062 | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. | 0.936 |
araE | araB | b2841 | b0063 | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | L-ribulokinase; Protein involved in carbohydrate catabolic process; Belongs to the ribulokinase family. | 0.958 |
araE | araD | b2841 | b0061 | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D- xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon- carbon bond cleavage analogous to a class II aldolase reaction). | 0.935 |
araE | crp | b2841 | b3357 | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | cAMP-activated global transcription factor, mediator of catabolite repression; A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site [...] | 0.473 |
araE | lacI | b2841 | b0345 | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. | 0.624 |
crp | araE | b3357 | b2841 | cAMP-activated global transcription factor, mediator of catabolite repression; A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site [...] | Arabinose transporter; Uptake of arabinose across the boundary membrane with the concomitant transport of protons into the cell (symport system). | 0.473 |
crp | lacI | b3357 | b0345 | cAMP-activated global transcription factor, mediator of catabolite repression; A global transcription regulator. Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACATTT-3') to directly regulate the transcription of about 300 genes in about 200 operons and indirectly regulate the expression of about half the genome. There are 3 classes of CRP promoters; class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)-binding site, whereas in class II promoters the single CRP- and RNAP-binding site [...] | Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. | 0.823 |
exbB | exbD | b3006 | b3005 | Membrane spanning protein in TonB-ExbB-ExbD complex; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB. | Membrane spanning protein in TonB-ExbB-ExbD complex; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. | 0.999 |
exbD | exbB | b3005 | b3006 | Membrane spanning protein in TonB-ExbB-ExbD complex; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. | Membrane spanning protein in TonB-ExbB-ExbD complex; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB. | 0.999 |