node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccmA | ccmB | b2201 | b2200 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmA | ccmC | b2201 | b2199 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmA | ccmD | b2201 | b2198 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Cytochrome c biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmA | ccmE | b2201 | b2197 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Periplasmic heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH; Belongs to the CcmE/CycJ family. | 0.998 |
ccmA | ccmF | b2201 | b2196 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.992 |
ccmA | dsbE | b2201 | b2195 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Periplasmic thioredoxin of cytochrome c-type biogenesis; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD. | 0.989 |
ccmA | lolC | b2201 | b1116 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Lipoprotein-releasing system transmembrane protein; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA. | 0.568 |
ccmA | lolD | b2201 | b1117 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA. | 0.626 |
ccmA | lolE | b2201 | b1118 | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | Lipoprotein-releasing system transmembrane protein; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA. | 0.573 |
ccmB | ccmA | b2200 | b2201 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | 0.999 |
ccmB | ccmC | b2200 | b2199 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmB | ccmD | b2200 | b2198 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Cytochrome c biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |
ccmB | ccmE | b2200 | b2197 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Periplasmic heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH; Belongs to the CcmE/CycJ family. | 0.999 |
ccmB | ccmF | b2200 | b2196 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme lyase, CcmF subunit; Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase. | 0.993 |
ccmB | dsbE | b2200 | b2195 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Periplasmic thioredoxin of cytochrome c-type biogenesis; Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase. DsbE is maintained in a reduced state by DsbD. | 0.985 |
ccmB | lolC | b2200 | b1116 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Lipoprotein-releasing system transmembrane protein; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA. | 0.540 |
ccmB | lolD | b2200 | b1117 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA. | 0.541 |
ccmB | lolE | b2200 | b1118 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Lipoprotein-releasing system transmembrane protein; Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA. | 0.540 |
ccmC | ccmA | b2199 | b2201 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme export ABC transporter ATPase; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. | 0.999 |
ccmC | ccmB | b2199 | b2200 | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | Heme export ABC transporter permease; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. | 0.999 |