7 items (Escherichia coli K12) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Input:
	ykgG	LutC family protein; Putative transporter. (231 aa)
	ldhA	Fermentative D-lactate dehydrogenase, NAD-dependent; Fermentative lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa)
	lldP	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force. (551 aa)
	lldD	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate. (396 aa)
	ykgF	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component. (475 aa)
	ykgE	Cysteine-rich LutA family protein; Putative dehydrogenase subunit. (239 aa)
	lacZ	beta-D-galactosidase; Protein involved in carbohydrate catabolic process; Belongs to the glycosyl hydrolase 2 family. (1024 aa)

Your Current Organism:

Escherichia coli K12

NCBI taxonomy Id: 511145
Other names: E. coli str. K-12 substr. MG1655, Escherichia coli MG1655, Escherichia coli str. K-12 substr. MG1655, Escherichia coli str. K12 substr. MG1655, Escherichia coli str. MG1655, Escherichia coli strain MG1655

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ldhA	lldD	b1380	b3605	Fermentative D-lactate dehydrogenase, NAD-dependent; Fermentative lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	0.983
ldhA	lldP	b1380	b3603	Fermentative D-lactate dehydrogenase, NAD-dependent; Fermentative lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	0.564
lldD	ldhA	b3605	b1380	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	Fermentative D-lactate dehydrogenase, NAD-dependent; Fermentative lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.983
lldD	lldP	b3605	b3603	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	0.999
lldD	ykgE	b3605	b0306	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	0.446
lldD	ykgF	b3605	b0307	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	0.656
lldP	ldhA	b3603	b1380	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	Fermentative D-lactate dehydrogenase, NAD-dependent; Fermentative lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.564
lldP	lldD	b3603	b3605	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	0.999
lldP	ykgE	b3603	b0306	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	0.587
lldP	ykgF	b3603	b0307	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	0.652
lldP	ykgG	b3603	b0308	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	LutC family protein; Putative transporter.	0.536
ykgE	lldD	b0306	b3605	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	0.446
ykgE	lldP	b0306	b3603	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	0.587
ykgE	ykgF	b0306	b0307	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	0.999
ykgE	ykgG	b0306	b0308	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	LutC family protein; Putative transporter.	0.999
ykgF	lldD	b0307	b3605	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Seems to be a primary dehydrogenase in the respiratory chain. To a lesser extent, can also oxidize DL-alpha-hydroxybutyrate, but not D-lactate.	0.656
ykgF	lldP	b0307	b3603	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	0.652
ykgF	ykgE	b0307	b0306	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	Cysteine-rich LutA family protein; Putative dehydrogenase subunit.	0.999
ykgF	ykgG	b0307	b0308	Ferridoxin-like LutB family protein; putative electron transport chain YkgEFG component.	LutC family protein; Putative transporter.	0.999
ykgG	lldP	b0308	b3603	LutC family protein; Putative transporter.	L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate. Seems to be driven by a proton motive force.	0.536

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