Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ascG | cra | b2714 | b0080 | Asc operon transcriptional repressor; Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | 0.437 |
| ascG | rbsR | b2714 | b3753 | Asc operon transcriptional repressor; Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. | Transcriptional repressor of ribose metabolism; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon. | 0.419 |
| ascG | treR | b2714 | b4241 | Asc operon transcriptional repressor; Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. | Trehalose 6-phosphate-inducible trehalose regulon transcriptional repressor; Repressor of the treBC operon. It is able to bind trehalose- 6-phosphate and trehalose. | 0.479 |
| cra | ascG | b0080 | b2714 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Asc operon transcriptional repressor; Repressor of the asc operon. The cryptic operon is activated by the insertion of IS186 into the ascG gene. | 0.437 |
| cra | cytR | b0080 | b3934 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Anti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. | 0.491 |
| cra | ebgR | b0080 | b3075 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | 0.730 |
| cra | galR | b0080 | b2837 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Galactose-inducible d-galactose regulon transcriptional repressor; Repressor of the galactose operon. Binds galactose as an inducer. | 0.534 |
| cra | galS | b0080 | b2151 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Galactose- and fucose-inducible galactose regulon transcriptional isorepressor; Repressor of the mgl operon. Binds galactose and D-fucose as inducers. GalS binds to an operator DNA sequence within its own coding sequence (corresponding to residues 15 to 20). | 0.465 |
| cra | lacI | b0080 | b0345 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. | 0.481 |
| cra | purR | b0080 | b1658 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Transcriptional repressor, hypoxanthine-binding; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. In addition, it participates in the regulation or coregulation of genes involved in de novo pyrimidine nucleotide biosynthesis, salvage and uptake (pyrC, pyrD, carAB and codBA), and of several genes encoding enzymes necessary for nucleotide and polyamine biosynthesis (prsA, glyA, gcvTHP, speA, glnB). Binds to a 16-bp palindromic sequence located within the promoter region [...] | 0.520 |
| cra | rbsR | b0080 | b3753 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Transcriptional repressor of ribose metabolism; Transcriptional repressor for the ribose rbsDACBK operon. RbsR binds to a region of perfect dyad symmetry spanning the rbs operon transcriptional start site. The affinity for the rbs operator is reduced by addition of ribose, consistent with ribose being the inducer of the operon. | 0.442 |
| cra | treR | b0080 | b4241 | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | Trehalose 6-phosphate-inducible trehalose regulon transcriptional repressor; Repressor of the treBC operon. It is able to bind trehalose- 6-phosphate and trehalose. | 0.437 |
| cytR | cra | b3934 | b0080 | Anti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | 0.491 |
| cytR | lacI | b3934 | b0345 | Anti-activator for CytR-CRP nucleoside utilization regulon; This protein negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins. Binds cytidine and adenosine as effectors. | Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. | 0.497 |
| ebgR | cra | b3075 | b0080 | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | Transcriptional repressor-activator for carbon metabolism; Global transcriptional regulator, which plays an important role in the regulation of carbon metabolism. Activates transcription of genes encoding biosynthetic and oxidative enzymes (involved in Krebs cycle, glyoxylate shunt and gluconeogenesis, such as ppsA and fbp). Represses genes involved in sugar catabolism, such as fruB, pfkA, pykF and adhE. Binds asymmetrically to the two half-sites of its operator. | 0.730 |
| ebgR | galR | b3075 | b2837 | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | Galactose-inducible d-galactose regulon transcriptional repressor; Repressor of the galactose operon. Binds galactose as an inducer. | 0.441 |
| ebgR | gntR | b3075 | b3438 | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | D-gluconate inducible gluconate regulon transcriptional repressor; Negative regulator for the gluconate utilization system GNT- I, the gntUKR operon. | 0.773 |
| ebgR | idnR | b3075 | b4264 | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | Transcriptional repressor, 5-gluconate-binding; Idn operon regulator. May repress gntKU and gntT genes when growing on L-idonate. | 0.878 |
| ebgR | lacI | b3075 | b0345 | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | Lactose-inducible lac operon transcriptional repressor; Repressor of the lactose operon. Binds allolactose as an inducer. | 0.472 |
| ebgR | malI | b3075 | b1620 | Transcriptional repressor; Repressor for beta galactosidase alpha and beta subunits (ebgA and ebgC). Binds lactose as an inducer. | Transcriptional repressor of Mal regulon; Repressor for the malX and malY genes. Also regulates its own expression. Binds maltose as an inducer. | 0.771 |
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