(57 nodes) Nucleotide excision repair network (Juglans regia)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108981134	RING-box protein 1a. (118 aa)
	LOC108982749	Cullin-4-like; Belongs to the cullin family. (827 aa)
	LOC108983738	DNA polymerase epsilon subunit 3. (185 aa)
	LOC108983896	DNA polymerase I B, chloroplastic/mitochondrial-like isoform X1. (1057 aa)
	LOC108984440	Replication factor C subunit 2. (334 aa)
	LOC108985777	Probable RNA polymerase II transcription factor B subunit 1-3 isoform X1. (611 aa)
	LOC108985792	Ubiquitin receptor RAD23b-like. (374 aa)
	LOC108986111	DNA repair helicase XPD. (758 aa)
	LOC108986907	DNA damage-binding protein 1. (1089 aa)
	LOC108987071	Ubiquitin receptor RAD23c-like. (380 aa)
	LOC108987083	Ubiquitin receptor RAD23c-like. (380 aa)
	LOC108988120	DNA ligase. (1442 aa)
	LOC108988169	Ubiquitin receptor RAD23c-like. (383 aa)
	LOC108988190	DNA repair protein RAD4 isoform X1. (992 aa)
	LOC108988327	RNA polymerase II transcription factor B subunit 4 isoform X1. (290 aa)
	LOC108989700	DNA ligase. (784 aa)
	LOC108990087	General transcription factor IIH subunit. (423 aa)
	LOC108990252	Cullin-4-like isoform X1; Belongs to the cullin family. (814 aa)
	LOC108990627	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (451 aa)
	LOC108991783	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (323 aa)
	LOC108993247	Uncharacterized protein LOC108993247 isoform X1. (192 aa)
	LOC108993564	DNA polymerase I A, chloroplastic/mitochondrial-like isoform X1. (1073 aa)
	LOC108994160	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (637 aa)
	LOC108995412	Replication factor C subunit 1. (960 aa)
	LOC108995956	Protein CHROMATIN REMODELING 8 isoform X1. (1233 aa)
	LOC108996361	DNA polymerase. (1087 aa)
	LOC108996617	DNA polymerase delta subunit 4. (121 aa)
	LOC108997079	DNA repair protein UVH3 isoform X1. (1693 aa)
	LOC108997443	DNA repair helicase XPB1. (767 aa)
	LOC108997538	Uncharacterized protein LOC108997538 isoform X1. (795 aa)
	LOC108998915	Replication protein A 32 kDa subunit B isoform X1. (277 aa)
	LOC109000861	Replication factor C subunit 3. (354 aa)
	LOC109001448	Uncharacterized protein At4g28440. (153 aa)
	LOC109001537	Uncharacterized protein LOC109001537 isoform X1. (761 aa)
	LOC109002051	Protein DAMAGED DNA-BINDING 2 isoform X1. (573 aa)
	LOC109003372	DNA repair endonuclease UVH1. (986 aa)
	LOC109003593	Cyclin-dependent kinase D-3-like; Belongs to the protein kinase superfamily. (407 aa)
	LOC109003774	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (266 aa)
	LOC109004017	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (873 aa)
	LOC109004847	Nucleolar and coiled-body phosphoprotein 1. (564 aa)
	LOC109007378	Replication protein A 14 kDa subunit B-like. (106 aa)
	LOC109007405	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
	LOC109008161	DNA excision repair protein ERCC-1-like. (389 aa)
	LOC109008755	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2218 aa)
	LOC109008887	Replication factor C subunit 3 isoform X1. (368 aa)
	LOC109008893	Replication factor C subunit 2. (342 aa)
	LOC109009014	Protein DAMAGED DNA-BINDING 2-like isoform X1. (571 aa)
	LOC109009026	RING-box protein 1a-like. (118 aa)
	LOC109009746	cyclin-H1-1; Belongs to the cyclin family. (337 aa)
	LOC109010990	RNA polymerase II transcription factor B subunit 5. (70 aa)
	LOC109012089	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (543 aa)
	LOC109012385	DNA excision repair protein ERCC-8-like isoform X1. (447 aa)
	LOC109013050	Replication protein A 32 kDa subunit A-like isoform X1. (283 aa)
	LOC109014000	Replication factor C subunit 1. (954 aa)
	LOC109019188	Replication protein A 14 kDa subunit B-like. (106 aa)
	LOC109020747	DNA polymerase delta small subunit-like. (457 aa)
	LOC109020969	Cyclin-dependent kinase D-3-like isoform X1; Belongs to the protein kinase superfamily. (415 aa)

Your Current Organism:

Juglans regia

NCBI taxonomy Id: 51240
Other names: English walnut, J. regia, Juglans regia L.

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108981134	LOC108982749	A0A2I4DKT1	A0A2I4DRH3	RING-box protein 1a.	Cullin-4-like; Belongs to the cullin family.	0.965
LOC108981134	LOC108983738	A0A2I4DKT1	A0A2I4DV53	RING-box protein 1a.	DNA polymerase epsilon subunit 3.	0.736
LOC108981134	LOC108984440	A0A2I4DKT1	A0A2I4DXS7	RING-box protein 1a.	Replication factor C subunit 2.	0.725
LOC108981134	LOC108985777	A0A2I4DKT1	A0A2I4E2X0	RING-box protein 1a.	Probable RNA polymerase II transcription factor B subunit 1-3 isoform X1.	0.643
LOC108981134	LOC108985792	A0A2I4DKT1	A0A2I4E318	RING-box protein 1a.	Ubiquitin receptor RAD23b-like.	0.744
LOC108981134	LOC108986111	A0A2I4DKT1	A0A2I4E457	RING-box protein 1a.	DNA repair helicase XPD.	0.708
LOC108981134	LOC108986907	A0A2I4DKT1	A0A2I4E775	RING-box protein 1a.	DNA damage-binding protein 1.	0.984
LOC108981134	LOC108987071	A0A2I4DKT1	A0A2I4E7U0	RING-box protein 1a.	Ubiquitin receptor RAD23c-like.	0.744
LOC108981134	LOC108987083	A0A2I4DKT1	A0A2I4E7V6	RING-box protein 1a.	Ubiquitin receptor RAD23c-like.	0.744
LOC108981134	LOC108988120	A0A2I4DKT1	A0A2I4EBL9	RING-box protein 1a.	DNA ligase.	0.627
LOC108981134	LOC108988169	A0A2I4DKT1	A0A2I4EBT2	RING-box protein 1a.	Ubiquitin receptor RAD23c-like.	0.744
LOC108981134	LOC108988190	A0A2I4DKT1	A0A2I4EBW4	RING-box protein 1a.	DNA repair protein RAD4 isoform X1.	0.805
LOC108981134	LOC108989700	A0A2I4DKT1	A0A2I4EHT2	RING-box protein 1a.	DNA ligase.	0.619
LOC108981134	LOC108990252	A0A2I4DKT1	A0A2I4EJX2	RING-box protein 1a.	Cullin-4-like isoform X1; Belongs to the cullin family.	0.965
LOC108981134	LOC108991783	A0A2I4DKT1	A0A2I4EQN7	RING-box protein 1a.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.635
LOC108981134	LOC108993247	A0A2I4DKT1	A0A2I4EW65	RING-box protein 1a.	Uncharacterized protein LOC108993247 isoform X1.	0.743
LOC108981134	LOC108995956	A0A2I4DKT1	A0A2I4F6A7	RING-box protein 1a.	Protein CHROMATIN REMODELING 8 isoform X1.	0.769
LOC108981134	LOC108996361	A0A2I4DKT1	A0A2I4F7Z3	RING-box protein 1a.	DNA polymerase.	0.684
LOC108981134	LOC108997079	A0A2I4DKT1	A0A2I4FAQ5	RING-box protein 1a.	DNA repair protein UVH3 isoform X1.	0.668
LOC108981134	LOC108997443	A0A2I4DKT1	A0A2I4FCA6	RING-box protein 1a.	DNA repair helicase XPB1.	0.625