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AMIS_10490 AMIS_10490 purA purA purD purD ndk ndk AMIS_1150 AMIS_1150 purS purS purQ purQ purL purL purF purF purM purM AMIS_12900 AMIS_12900 surE surE AMIS_14110 AMIS_14110 AMIS_16860 AMIS_16860 AMIS_18550 AMIS_18550 AMIS_18560 AMIS_18560 AMIS_28770 AMIS_28770 tmk tmk AMIS_36960 AMIS_36960 AMIS_39110 AMIS_39110 AMIS_43110 AMIS_43110 AMIS_44910 AMIS_44910 AMIS_47030 AMIS_47030 AMIS_5080 AMIS_5080 AMIS_56960 AMIS_56960 dcd dcd pyrG pyrG AMIS_620 AMIS_620 gmk gmk pyrF pyrF pyrD pyrD carB carB carA carA pyrC pyrC pyrB pyrB pyrR pyrR apt apt dut dut AMIS_68910 AMIS_68910 guaB guaB AMIS_6920 AMIS_6920 guaA guaA AMIS_7110 AMIS_7110 purN purN purH purH AMIS_74680 AMIS_74680 add add AMIS_74810 AMIS_74810 AMIS_74820 AMIS_74820 pyrE pyrE AMIS_78590 AMIS_78590 purC purC purK purK purE purE AMIS_8970 AMIS_8970
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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AMIS_10490Putative thymidylate kinase. (247 aa)
purAPutative adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa)
purDPutative phosphoribosylglycinamide synthetase; Belongs to the GARS family. (413 aa)
ndkPutative nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa)
AMIS_1150Putative adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (473 aa)
purSPutative phosphoribosylformylglycinamidine synthase PurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and [...] (87 aa)
purQPutative phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (235 aa)
purLPutative phosphoribosyl formylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (792 aa)
purFPutative phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (517 aa)
purMPutative phosphoribosylaminoimidazole synthetase. (383 aa)
AMIS_12900Putative 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Belongs to the 5'-nucleotidase family. (596 aa)
surEPutative stationary phase survival protein SurE. (278 aa)
AMIS_14110Putative PfkB-family carbohydrate kinase. (325 aa)
AMIS_16860Putative flavohemoprotein. (590 aa)
AMIS_18550Putative ribonucleoside-diphosphate reductase small subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (331 aa)
AMIS_18560Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (786 aa)
AMIS_28770Putative phosphoribulokinase/uridine kinase. (220 aa)
tmkPutative thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (665 aa)
AMIS_36960Hypothetical protein; CBS domain. (145 aa)
AMIS_39110Putative thymidine kinase. (205 aa)
AMIS_43110Putative inositol-5'-monophosphate dehydrogenase. (496 aa)
AMIS_44910Putative phosphoribulokinase/uridine kinase. (222 aa)
AMIS_47030Putative adenosine deaminase. (333 aa)
AMIS_5080Putative 5'-nucleotidase. (1590 aa)
AMIS_56960Putative thymidine kinase. (202 aa)
dcdPutative deoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (193 aa)
pyrGPutative CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (564 aa)
AMIS_620Putative phosphoribosyltransferase. (180 aa)
gmkPutative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (199 aa)
pyrFPutative orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (276 aa)
pyrDPutative dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (342 aa)
carBPutative carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1105 aa)
carAPutative carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (383 aa)
pyrCPutative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (420 aa)
pyrBPutative aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
pyrRPutative pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (194 aa)
aptPutative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa)
dutPutative deoxyuridine 5'-triphosphate pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (168 aa)
AMIS_68910Putative vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (972 aa)
guaBPutative inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (495 aa)
AMIS_6920Putative inosine-5'-monophosphate dehydrogenase. (372 aa)
guaAPutative GMP synthase; Catalyzes the synthesis of GMP from XMP. (515 aa)
AMIS_7110Putative 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (608 aa)
purNPutative phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (205 aa)
purHPutative bifunctional purine biosynthesis protein. (521 aa)
AMIS_74680Putative uracil phosphoribosyltransferase; Belongs to the UPRTase family. (210 aa)
addPutative adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (373 aa)
AMIS_74810Putative thymidine phosphorylase. (425 aa)
AMIS_74820Putative cytidine/deoxycytidine deaminase. (238 aa)
pyrEPutative orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (174 aa)
AMIS_78590Putative purine nucleoside phosphorylase. (237 aa)
purCPutative phosphoribosylaminoimidazole-succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. (279 aa)
purKPutative phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (380 aa)
purEPutative phosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa)
AMIS_8970Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (199 aa)
Your Current Organism:
Actinoplanes missouriensis
NCBI taxonomy Id: 512565
Other names: A. missouriensis 431, Actinoplanes missouriensis 431, Actinoplanes missouriensis str. 431, Actinoplanes missouriensis strain 431
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