(13 nodes) Mixed, incl. Quorum sensing, and NAD+ binding network (Eubacterium eligens)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACR72641.1	Hypothetical protein; Psort-B: Unknown cell location. (429 aa)
	ACR72642.1	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87. (63 aa)
	ACR72643.1	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase. (208 aa)
	ACR72644.1	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase. (325 aa)
	ACR72645.1	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0419 ATPase involved in DNA repair; superfamily:IPR000157. (687 aa)
	ACR72646.1	Arsenate reductase; Psort-B: Cytoplasmic, score:8.87; COG0394 Protein-tyrosine-phosphatase; HMMPfam:IPR000106; HMMPanther:IPR000106; HMMSmart:IPR000106; superfamily:IPR000106; K03741 arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (136 aa)
	ACR72647.1	Hypothetical protein; Psort-B: Unknown cell location; NOG31153 non supervised orthologous group. (135 aa)
	ACR72649.1	Hypothetical protein; Psort-B: Unknown cell location; COG0642 Signal transduction histidine kinase; HMMPfam:IPR003594; HMMPfam:IPR003661; Gene3D:IPR003594; HMMSmart:IPR003594; HMMSmart:IPR003661; superfamily:IPR003594; superfamily:IPR009082. (458 aa)
	ACR72650.1	Two-component system, OmpR family, response regulator ResD; Psort-B: Cytoplasmic, score:9.98; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; HMMPfam:IPR001789; HMMPfam:IPR001867; BlastProDom:IPR001789; BlastProDom:IPR001867; HMMSmart:IPR001789; superfamily:IPR011006; K07775 two-component system, OmpR family, response regulator ResD. (220 aa)
	ACR72651.1	Antibiotic transport system permease protein; Psort-B: CytoplasmicMembrane, score:9.99; NOG31276 non supervised orthologous group; K09686 antibiotic transport system permease protein. (246 aa)
	ACR72652.1	Antibiotic transport system permease protein; Psort-B: CytoplasmicMembrane, score:9.99; NOG17940 non supervised orthologous group; K09686 antibiotic transport system permease protein. (243 aa)
	ACR72653.1	Antibiotic transport system ATP-binding protein; Psort-B: CytoplasmicMembrane, score:9.49; COG1131 ABC-type multidrug transport system, ATPase component; HMMPfam:IPR003439; BlastProDom:IPR003439; HMMSmart:IPR003593; ScanRegExp:IPR003439; K09687 antibiotic transport system ATP-binding protein. (237 aa)
	ACR72654.1	Putative transcriptional regulator; Psort-B: Unknown cell location; COG1476 Predicted transcriptional regulators; HMMPfam:IPR001387; HMMSmart:IPR001387; superfamily:IPR010982; K07729 putative transcriptional regulator. (97 aa)

Your Current Organism:

Eubacterium eligens

NCBI taxonomy Id: 515620
Other names: Eubacterium eligens ATCC 27750, [. eligens ATCC 27750, [Eubacterium] eligens ATCC 27750

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACR72641.1	ACR72642.1	EUBELI_01650	EUBELI_01651	Hypothetical protein; Psort-B: Unknown cell location.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	0.768
ACR72641.1	ACR72643.1	EUBELI_01650	EUBELI_01652	Hypothetical protein; Psort-B: Unknown cell location.	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	0.632
ACR72641.1	ACR72644.1	EUBELI_01650	EUBELI_01653	Hypothetical protein; Psort-B: Unknown cell location.	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	0.623
ACR72641.1	ACR72645.1	EUBELI_01650	EUBELI_01654	Hypothetical protein; Psort-B: Unknown cell location.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0419 ATPase involved in DNA repair; superfamily:IPR000157.	0.623
ACR72642.1	ACR72641.1	EUBELI_01651	EUBELI_01650	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	Hypothetical protein; Psort-B: Unknown cell location.	0.768
ACR72642.1	ACR72643.1	EUBELI_01651	EUBELI_01652	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	0.636
ACR72642.1	ACR72644.1	EUBELI_01651	EUBELI_01653	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	0.628
ACR72642.1	ACR72645.1	EUBELI_01651	EUBELI_01654	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0419 ATPase involved in DNA repair; superfamily:IPR000157.	0.627
ACR72643.1	ACR72641.1	EUBELI_01652	EUBELI_01650	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	Hypothetical protein; Psort-B: Unknown cell location.	0.632
ACR72643.1	ACR72642.1	EUBELI_01652	EUBELI_01651	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	0.636
ACR72643.1	ACR72644.1	EUBELI_01652	EUBELI_01653	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	0.762
ACR72643.1	ACR72645.1	EUBELI_01652	EUBELI_01654	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0419 ATPase involved in DNA repair; superfamily:IPR000157.	0.762
ACR72643.1	ACR72646.1	EUBELI_01652	EUBELI_01655	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	Arsenate reductase; Psort-B: Cytoplasmic, score:8.87; COG0394 Protein-tyrosine-phosphatase; HMMPfam:IPR000106; HMMPanther:IPR000106; HMMSmart:IPR000106; superfamily:IPR000106; K03741 arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.	0.450
ACR72643.1	ACR72647.1	EUBELI_01652	EUBELI_01656	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	Hypothetical protein; Psort-B: Unknown cell location; NOG31153 non supervised orthologous group.	0.526
ACR72644.1	ACR72641.1	EUBELI_01653	EUBELI_01650	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	Hypothetical protein; Psort-B: Unknown cell location.	0.623
ACR72644.1	ACR72642.1	EUBELI_01653	EUBELI_01651	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87.	0.628
ACR72644.1	ACR72643.1	EUBELI_01653	EUBELI_01652	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	methylated-DNA-[protein]-cysteine S-methyltransferase; Psort-B: Cytoplasmic, score:8.87; COG0350 Methylated DNA-protein cysteine methyltransferase; HMMPfam:IPR007351; HMMPfam:IPR014048; Gene3D:IPR011991; HMMPanther:IPR014048; HMMTigr:IPR014048; superfamily:IPR014048; K00567 methylated-DNA-[protein]-cysteine S-methyltransferase.	0.762
ACR72644.1	ACR72645.1	EUBELI_01653	EUBELI_01654	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	Hypothetical protein; Psort-B: Cytoplasmic, score:8.87; COG0419 ATPase involved in DNA repair; superfamily:IPR000157.	0.773
ACR72644.1	ACR72646.1	EUBELI_01653	EUBELI_01655	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	Arsenate reductase; Psort-B: Cytoplasmic, score:8.87; COG0394 Protein-tyrosine-phosphatase; HMMPfam:IPR000106; HMMPanther:IPR000106; HMMSmart:IPR000106; superfamily:IPR000106; K03741 arsenate reductase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.	0.429
ACR72644.1	ACR72647.1	EUBELI_01653	EUBELI_01656	3-hydroxybutyryl-CoA dehydrogenase; Psort-B: Unknown cell location; COG1250 3-hydroxyacyl-CoA dehydrogenase; HMMPfam:IPR006108; HMMPfam:IPR006176; Gene3D:IPR013328; superfamily:IPR008927; K00074 3-hydroxybutyryl-CoA dehydrogenase.	Hypothetical protein; Psort-B: Unknown cell location; NOG31153 non supervised orthologous group.	0.450