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Dtur_0031 Dtur_0031 dcd dcd Dtur_0444 Dtur_0444 Dtur_0588 Dtur_0588 tmk tmk thyX thyX tdk tdk upp upp dut dut pyrE pyrE surE surE pyrH pyrH Dtur_1324 Dtur_1324 pyrG pyrG Dtur_1383 Dtur_1383 Dtur_1471 Dtur_1471 pyrF pyrF pyrD pyrD Dtur_1573 Dtur_1573 pyrC pyrC pyrB pyrB pyrR pyrR Dtur_1698 Dtur_1698 carB carB carA carA Dtur_1794 Dtur_1794
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Dtur_0031PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase; KEGG: dth:DICTH_1732 uridine kinase. (555 aa)
dcdDeoxycytidine triphosphate deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (194 aa)
Dtur_0444PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dth:DICTH_0323 dihydroorotate dehydrogenase superfamily. (390 aa)
Dtur_0588PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: mta:Moth_0753 putative carbamoyl phosphate synthase large subunit. (320 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (207 aa)
thyXThymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (218 aa)
tdkPFAM: thymidine kinase; KEGG: dth:DICTH_0645 thymidine kinase. (198 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (147 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (189 aa)
surEStationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (252 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (249 aa)
Dtur_1324Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (131 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa)
Dtur_1383Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (749 aa)
Dtur_1471TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like; KEGG: dth:DICTH_1361 pyrimidine-nucleoside phosphorylase. (434 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa)
pyrDDihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate. (306 aa)
Dtur_1573PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: dth:DICTH_1463 dihydroorotate dehydrogenase electron transfer subunit. (252 aa)
pyrCDihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (431 aa)
pyrBKEGG: dth:DICTH_1465 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (311 aa)
pyrRPhosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (183 aa)
Dtur_1698TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: dth:DICTH_1590 anaerobic ribonucleoside-triphosphate reductase. (627 aa)
carBTIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; RimK domain protein ATP-grasp; KEGG: dth:DICTH_1672 carbamoyl-phosphate synthase, large subunit. (1054 aa)
carATIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: dth:DICTH_1673 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (358 aa)
Dtur_17945'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: dth:DICTH_1684 nucleotidase; Belongs to the 5'-nucleotidase family. (504 aa)
Your Current Organism:
Dictyoglomus turgidum
NCBI taxonomy Id: 515635
Other names: D. turgidum DSM 6724, Dictyoglomus turgidum DSM 6724, Dictyoglomus turgidum str. DSM 6724, Dictyoglomus turgidum strain DSM 6724
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