(24 nodes) Lysine degradation network (Podospora anserina)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A090CAH8	Uncharacterized protein. (531 aa)
	A0A090CVB2	Uncharacterized protein. (438 aa)
	A0A090CWN6	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (506 aa)
	A0A090D5D3	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1273 aa)
	PODANS_1_1980	Succinate-semialdehyde dehydrogenase. (528 aa)
	PODANS_1_5030	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 1. (444 aa)
	PODANS_1_20820	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 5. (894 aa)
	PODANS_0_1600	Podospora anserina S mat+ genomic DNA chromosome 5, supercontig 2. (555 aa)
	PODANS_1_13090	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 3. (491 aa)
	PODANS_4_4550	Podospora anserina S mat+ genomic DNA chromosome 4, supercontig 4; Belongs to the aldehyde dehydrogenase family. (476 aa)
	PODANS_4_8970	Podospora anserina S mat+ genomic DNA chromosome 4, supercontig 4. (502 aa)
	PODANS_7_3820	Podospora anserina S mat+ genomic DNA chromosome 7, supercontig 1. (674 aa)
	PODANS_7_1930	Podospora anserina S mat+ genomic DNA chromosome 7, supercontig 1; Belongs to the aldehyde dehydrogenase family. (495 aa)
	PODANS_7_7710	Putative histone-lysine N-methyltransferase, H3 lysine-36 specific SET2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (919 aa)
	PODANS_7_10210	ECHA mitochondrial enoyl-CoA hydratase encoded by the echA protein; Belongs to the enoyl-CoA hydratase/isomerase family. (304 aa)
	PODANS_1_8990	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 2; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	PODANS_1_10980	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (374 aa)
	PODANS_6_4990	Podospora anserina S mat+ genomic DNA chromosome 6, supercontig 2; Belongs to the aldehyde dehydrogenase family. (498 aa)
	PODANS_6_2240	Podospora anserina S mat+ genomic DNA chromosome 6, supercontig 2. (449 aa)
	PODANS_6_1590	Podospora anserina S mat+ genomic DNA chromosome 6, supercontig 2; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
	PODANS_2_3550	Podospora anserina S mat+ genomic DNA chromosome 2, supercontig 2. (440 aa)
	PODANS_2_11760	Podospora anserina S mat+ genomic DNA chromosome 2, supercontig 2. (304 aa)
	PODANS_5_5370	Podospora anserina S mat+ genomic DNA chromosome 5, supercontig 6. (420 aa)
	PODANS_5_5810	Dihydrolipoyl dehydrogenase. (505 aa)

Your Current Organism:

Podospora anserina

NCBI taxonomy Id: 515849
Other names: P. anserina S mat+, Podospora anserina FGSC #10383, Podospora anserina S mat+

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A090CAH8	A0A090CVB2	A0A090CAH8	A0A090CVB2	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A090CAH8	A0A090CWN6	A0A090CAH8	A0A090CWN6	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.918
A0A090CAH8	A0A090D5D3	A0A090CAH8	A0A090D5D3	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.935
A0A090CAH8	PODANS_1_20820	A0A090CAH8	B2ABI8	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 5.	0.909
A0A090CAH8	PODANS_1_5030	A0A090CAH8	B2AAT0	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 1.	0.900
A0A090CAH8	PODANS_7_3820	A0A090CAH8	B2AV81	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 7, supercontig 1.	0.908
A0A090CAH8	PODANS_7_7710	A0A090CAH8	B2AWM9	Uncharacterized protein.	Putative histone-lysine N-methyltransferase, H3 lysine-36 specific SET2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.918
A0A090CVB2	A0A090CAH8	A0A090CVB2	A0A090CAH8	Uncharacterized protein.	Uncharacterized protein.	0.900
A0A090CVB2	A0A090CWN6	A0A090CVB2	A0A090CWN6	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.900
A0A090CVB2	A0A090D5D3	A0A090CVB2	A0A090D5D3	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.900
A0A090CVB2	PODANS_1_1980	A0A090CVB2	B2A9W1	Uncharacterized protein.	Succinate-semialdehyde dehydrogenase.	0.512
A0A090CVB2	PODANS_1_20820	A0A090CVB2	B2ABI8	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 5.	0.900
A0A090CVB2	PODANS_1_5030	A0A090CVB2	B2AAT0	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 1, supercontig 1.	0.900
A0A090CVB2	PODANS_4_4550	A0A090CVB2	B2AQD1	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 4, supercontig 4; Belongs to the aldehyde dehydrogenase family.	0.466
A0A090CVB2	PODANS_5_5810	A0A090CVB2	B2VLD9	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.452
A0A090CVB2	PODANS_6_4990	A0A090CVB2	B2B1Z6	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 6, supercontig 2; Belongs to the aldehyde dehydrogenase family.	0.466
A0A090CVB2	PODANS_7_10210	A0A090CVB2	B2AXD7	Uncharacterized protein.	ECHA mitochondrial enoyl-CoA hydratase encoded by the echA protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.623
A0A090CVB2	PODANS_7_1930	A0A090CVB2	B2AVS7	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 7, supercontig 1; Belongs to the aldehyde dehydrogenase family.	0.466
A0A090CVB2	PODANS_7_3820	A0A090CVB2	B2AV81	Uncharacterized protein.	Podospora anserina S mat+ genomic DNA chromosome 7, supercontig 1.	0.906
A0A090CVB2	PODANS_7_7710	A0A090CVB2	B2AWM9	Uncharacterized protein.	Putative histone-lysine N-methyltransferase, H3 lysine-36 specific SET2; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.906