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pckG pckG Cpar_0368 Cpar_0368 Cpar_0560 Cpar_0560 lpd lpd Cpar_0857 Cpar_0857 Cpar_0858 Cpar_0858 Cpar_1008 Cpar_1008 Cpar_1009 Cpar_1009 Cpar_1438 Cpar_1438 sucC sucC mdh mdh Cpar_1686 Cpar_1686 sucD sucD Cpar_1875 Cpar_1875 Cpar_1876 Cpar_1876 Cpar_1916 Cpar_1916 Cpar_1917 Cpar_1917 Cpar_1918 Cpar_1918 Cpar_2025 Cpar_2025 Cpar_2026 Cpar_2026 Cpar_2027 Cpar_2027
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (621 aa)
Cpar_0368KEGG: cte:CT1834 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (447 aa)
Cpar_0560PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cte:CT1628 pyruvate flavodoxin/ferrodoxin oxidoreductase. (1178 aa)
lpdDihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (469 aa)
Cpar_0857Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa)
Cpar_0858Oxaloacetate decarboxylase; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cte:CT0834 oxaloacetate decarboxylase, alpha subunit. (627 aa)
Cpar_1008PFAM: ATP-grasp domain protein; KEGG: cte:CT1089 citrate lyase, subunit 1. (398 aa)
Cpar_1009PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: cte:CT1088 citrate lyase, subunit 2. (608 aa)
Cpar_1438TIGRFAM: aconitate hydratase 2; PFAM: aconitate hydratase domain protein; Aconitase B, N-terminal; KEGG: cte:CT0543 aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (854 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (310 aa)
Cpar_1686KEGG: cte:CT0351 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (741 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
Cpar_1875PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pvi:Cvib_1597 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (616 aa)
Cpar_1876PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: pvi:Cvib_1598 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (342 aa)
Cpar_1916CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cte:CT2040 succinate/fumarate oxidoreductase, putative. (283 aa)
Cpar_1917TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: cte:CT2041 succinate/fumarate oxidoreductase, iron-sulfur protein, putative. (345 aa)
Cpar_1918KEGG: cte:CT2042 succinate/fumarate oxidoreductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (567 aa)
Cpar_2025PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cte:CT2266 succinate dehydrogenase, iron-sulfur protein. (257 aa)
Cpar_2026KEGG: cte:CT2267 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (646 aa)
Cpar_2027TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: cte:CT2268 succinate dehydrogenase, cytochrome subunit, putative. (222 aa)
Your Current Organism:
Chlorobaculum parvum
NCBI taxonomy Id: 517417
Other names: C. parvum NCIB 8327, Chlorobaculum parvum NCIB 8327, Chlorobaculum parvum str. NCIB 8327, Chlorobaculum parvum strain NCIB 8327
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