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| | Cpar_0021 | TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cte:CT2256 geranylgeranyl hydrogenase. (383 aa) |
| | Cpar_0038 | TIGRFAM: siroheme synthase; KEGG: cte:CT2239 porphyrin biosynthesis protein, putative. (153 aa) |
| | Cpar_0039 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cte:CT2238 siroheme synthetase, putative; Belongs to the precorrin methyltransferase family. (459 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (621 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa) |
| | Cpar_0119 | TIGRFAM: chlorophyllide reductase subunit Z; PFAM: oxidoreductase/nitrogenase component 1; protein of unknown function DUF1197; KEGG: cte:CT2125 chlorophyllide reductase, BchZ subunit. (468 aa) |
| | gcvPB | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (495 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa) |
| | Cpar_0129 | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa) |
| | Cpar_0130 | TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: cte:CT2115 malonyl CoA-acyl carrier protein transacylase. (303 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (562 aa) |
| | hemL | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cte:CT2099 glutamate-1-semialdehyde 2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (431 aa) |
| | Cpar_0156 | PFAM: GCN5-related N-acetyltransferase; KEGG: cte:CT2212 acetyltransferase, GNAT family; Belongs to the acetyltransferase family. (157 aa) |
| | Cpar_0207 | PFAM: Nucleotidyl transferase; KEGG: cte:CT2159 mannose-1-phosphate guanylyltransferase, putative. (373 aa) |
| | bchN | Light-independent protochlorophyllide reductase, N subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (420 aa) |
| | bchB | Light-independent protochlorophyllide reductase, B subunit; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex. (535 aa) |
| | bchL | Light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (276 aa) |
| | Cpar_0225 | TIGRFAM: bacteriochlorophyll 4-vinyl reductase; KEGG: cte:CT2014 bacteriochlorophyll synthase, 23 kDa subunit. (190 aa) |
| | glgA | Glycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (488 aa) |
| | Cpar_0232 | PFAM: ROK family protein; KEGG: cte:CT2007 glucokinase, putative. (336 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | Cpar_0244 | PFAM: UbiA prenyltransferase; KEGG: cte:CT1992 bacteriochlorophyll a synthase. (339 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (294 aa) |
| | Cpar_0258 | KEGG: cte:CT1959 magnesium-protoporphyrin IX monomethyl ester oxidative cyclase, 66 kDa subunit; TIGRFAM: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (546 aa) |
| | Cpar_0259 | KEGG: cte:CT1958 magnesium-protoporphyrin IX monomethyl ester oxidative cyclase, 25 kDa subunit; TIGRFAM: magnesium protoporphyrin O-methyltransferase; PFAM: Magnesium-protoporphyrin IX methyltransferase domain protein; Methyltransferase type 11; Methyltransferase type 12. (232 aa) |
| | Cpar_0260 | KEGG: cte:CT1957 magnesium-protoporphyrin methyltransferase; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1279 aa) |
| | Cpar_0262 | KEGG: cte:CT1955 magnesium-chelatase, bacteriochlorophyll c-specific subunit; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase. (1267 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa) |
| | Cpar_0287 | PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cte:CT1921 cysteine synthase/cystathionine beta-synthase family protein. (456 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (434 aa) |
| | Cpar_0328 | PFAM: acyl-CoA reductase; Aldehyde Dehydrogenase_; KEGG: cte:CT1886 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (462 aa) |
| | Cpar_0334 | TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; KEGG: cte:CT1874 6-phosphogluconate dehydrogenase, decarboxylating, putative. (305 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (473 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (271 aa) |
| | Cpar_0338 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (674 aa) |
| | Cpar_0346 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1227 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (249 aa) |
| | Cpar_0355 | TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: cte:CT1848 O-succinylbenzoic acid--CoA ligase. (456 aa) |
| | menC | Mandelate racemase/muconate lactonizing protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (363 aa) |
| | menB | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (273 aa) |
| | menH | Alpha/beta hydrolase fold; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (276 aa) |
| | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (583 aa) |
| | menF | Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (469 aa) |
| | Cpar_0368 | KEGG: cte:CT1834 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (447 aa) |
| | Cpar_0375 | TIGRFAM: chlorophyllide reductase subunit Y; PFAM: oxidoreductase/nitrogenase component 1; KEGG: cte:CT1826 chlorophyllide reductase, BchY subunit. (415 aa) |
| | Cpar_0394 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cte:CT1565 para-aminobenzoate/anthranilate synthase glutamine amidotransferase. (187 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (261 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (279 aa) |
| | Cpar_0413 | PFAM: fructose-bisphosphate aldolase class-I; KEGG: tbd:Tbd_1513 fructose-bisphosphate aldolase. (340 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa) |
| | Cpar_0429 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cte:CT1777 bacteriochlorophyll c8 methyltransferase. (474 aa) |
| | Cpar_0430 | PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: cte:CT1776 bacteriochlorophyll c3(1) hydratase. (157 aa) |
| | Cpar_0434 | PFAM: ribulose bisphosphate carboxylase large chain; KEGG: cte:CT1772 ribulose-bisphosphate carboxylase large chain. (434 aa) |
| | Cpar_0440 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cte:CT1766 3-oxoacyl-(acyl-carrier-protein) reductase, putative. (245 aa) |
| | Cpar_0452 | KEGG: cte:CT0456 hypothetical protein. (510 aa) |
| | menG | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (241 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (137 aa) |
| | Cpar_0460 | PFAM: ferrochelatase; KEGG: cph:Cpha266_0481 ferrochelatase; Belongs to the ferrochelatase family. (333 aa) |
| | Cpar_0468 | TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cte:CT0473 glutamate synthase, small subunit. (482 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (202 aa) |
| | hisA | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: cte:CT0477 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (260 aa) |
| | Cpar_0484 | PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: cte:CT1708 hydrolase, haloacid dehalogenase-like family. (233 aa) |
| | Cpar_0507 | KEGG: cte:CT1682 pyruvate,orthophosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (916 aa) |
| | purD | KEGG: cte:CT1674 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. (425 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: cte:CT1671 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (256 aa) |
| | Cpar_0519 | PFAM: ribulose-phosphate 3-epimerase; KEGG: cte:CT1670 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa) |
| | pheA | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cte:CT1666 prephenate dehydratase. (281 aa) |
| | Cpar_0529 | PFAM: inositol monophosphatase; KEGG: cte:CT1661 extragenic suppressor protein SuhB. (288 aa) |
| | acsA | acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (659 aa) |
| | panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa) |
| | Cpar_0560 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cte:CT1628 pyruvate flavodoxin/ferrodoxin oxidoreductase. (1178 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (444 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | psd | Phosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (214 aa) |
| | Cpar_0576 | TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; PFAM: UbiA prenyltransferase; KEGG: cte:CT1610 bacteriochlorophyll a synthase. (330 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (351 aa) |
| | Cpar_0621 | KEGG: cte:CT0604 O-acetylhomoserine (thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. (429 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (356 aa) |
| | Cpar_0628 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: cte:CT0612 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (535 aa) |
| | Cpar_0629 | PFAM: aconitate hydratase domain protein; KEGG: cte:CT0613 3-isopropylmalate dehydratase small subunit; Belongs to the LeuD family. (191 aa) |
| | Cpar_0630 | Homoaconitate hydratase family protein; KEGG: cte:CT0614 3-isopropylmalate dehydratase large subunit; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein; Belongs to the aconitase/IPM isomerase family. (431 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (351 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa) |
| | Cpar_0633 | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: cte:CT0617 acetolactate synthase small subunit. (159 aa) |
| | Cpar_0634 | TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: cte:CT0618 acetolactate synthase large subunit. (573 aa) |
| | ilvD | KEGG: cte:CT0619 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (560 aa) |
| | Cpar_0650 | PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cte:CT0649 carotenoid isomerase, putative. (503 aa) |
| | Cpar_0672 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cte:CT0700 cysteine synthase. (310 aa) |
| | Cpar_0673 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cte:CT0701 trans-sulfuration enzyme family protein. (380 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cte:CT0718 N-(5'-phosphoribosyl)-anthranilate isomerase; Belongs to the TrpF family. (221 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (404 aa) |
| | Cpar_0692 | PFAM: Nucleotidyl transferase; KEGG: cte:CT0727 glucose-1-phosphate thymidylyltransferase. (325 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: cte:CT0735 imidazoleglycerol-phosphate dehydratase. (194 aa) |
| | Cpar_0710 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa) |
| | lpd | Dihydrolipoamide dehydrogenase; Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (469 aa) |
| | bchI | Magnesium chelatase ATPase subunit I; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (390 aa) |
| | bchD | Magnesium chelatase ATPase subunit D; Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (619 aa) |
| | bchH | Magnesium chelatase, H subunit; Involved in bacteriochlorophyll pigment biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg- protoroporphyrin IX. (1272 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (494 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (410 aa) |
| | hemB | Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen; Belongs to the ALAD family. (328 aa) |
| | hemD | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (312 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa) |
| | Cpar_0741 | KEGG: cte:CT1423 chlorophyllide reductase, BchX subunit; TIGRFAM: chlorophyllide reductase iron protein subunit X; PFAM: NifH/frxC-family protein; Sigma-70 region 4 type 2; Belongs to the NifH/BchL/ChlL family. (365 aa) |
| | Cpar_0742 | TIGRFAM: chlorophyll synthesis pathway, BchC; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cte:CT1422 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase. (339 aa) |
| | Cpar_0743 | PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: cte:CT1421 2-vinyl bacteriochlorophyllide hydratase. (159 aa) |
| | Cpar_0751 | Carotene 7,8-desaturase; PFAM: amine oxidase; KEGG: cte:CT1414 zeta-carotene desaturase. (453 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (367 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (187 aa) |
| | Cpar_0777 | PFAM: Squalene/phytoene synthase; KEGG: cte:CT1386 phytoene desaturase. (310 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (431 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (277 aa) |
| | Cpar_0816 | TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cte:CT1340 CDP-diacylglycerol-serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (270 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (84 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (252 aa) |
| | Cpar_0829 | KEGG: cph:Cpha266_1166 acetyl-CoA carboxylase alpha subunit-like. (591 aa) |
| | Cpar_0833 | PFAM: Transketolase central region; Transketolase domain protein; KEGG: cte:CT0804 transketolase, C-terminal subunit. (327 aa) |
| | Cpar_0836 | Carotene 7,8-desaturase; PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cte:CT0807 phytoene desaturase. (461 aa) |
| | Cpar_0857 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa) |
| | Cpar_0870 | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (360 aa) |
| | ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (285 aa) |
| | Cpar_0911 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: cte:CT0889 phosphoglycolate phosphatase. (224 aa) |
| | Cpar_0913 | PFAM: phospholipid/glycerol acyltransferase; KEGG: pvi:Cvib_1002 phospholipid/glycerol acyltransferase. (271 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (759 aa) |
| | Cpar_0980 | KEGG: cte:CT1050 ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase. (144 aa) |
| | Cpar_0983 | KEGG: cte:CT1053 fructose-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II. (323 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: cte:CT1055 argininosuccinate lyase. (463 aa) |
| | argG | PFAM: argininosuccinate synthase; ExsB family protein; KEGG: cte:CT1114 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa) |
| | Cpar_0988 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (336 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (301 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (427 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (338 aa) |
| | Cpar_1008 | PFAM: ATP-grasp domain protein; KEGG: cte:CT1089 citrate lyase, subunit 1. (398 aa) |
| | Cpar_1009 | PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: cte:CT1088 citrate lyase, subunit 2. (608 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (392 aa) |
| | Cpar_1021 | NmrA family protein; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility domain; KEGG: cte:CT1063 hypothetical protein. (343 aa) |
| | Cpar_1043 | KEGG: cte:CT1077 hypothetical protein. (193 aa) |
| | adk | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) |
| | Cpar_1146 | PFAM: Polyprenyl synthetase; KEGG: cte:CT1206 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (324 aa) |
| | Cpar_1209 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: cph:Cpha266_1144 HAD-superfamily hydrolase, subfamily IA, variant 1. (219 aa) |
| | Cpar_1222 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: cte:CT0989 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (434 aa) |
| | pgi | PFAM: phosphoglucose isomerase (PGI); KEGG: cte:CT0988 glucose-6-phosphate isomerase; Belongs to the GPI family. (559 aa) |
| | Cpar_1230 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (353 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (313 aa) |
| | Cpar_1246 | PFAM: aminotransferase class I and II; KEGG: cte:CT0966 aspartate aminotransferase, putative. (400 aa) |
| | purC | KEGG: cte:CT0960 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (235 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: cte:CT1256 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa) |
| | Cpar_1271 | TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; PFAM: UbiA prenyltransferase; KEGG: cte:CT1270 bacteriochlorophyll synthase, 34 kDa subunit. (355 aa) |
| | Cpar_1277 | TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase GroES domain protein; KEGG: cte:CT1275 alcohol dehydrogenase, zinc-containing. (342 aa) |
| | Cpar_1289 | PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: afw:Anae109_3601 short-chain dehydrogenase/reductase SDR. (247 aa) |
| | Cpar_1317 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: cte:CT0756 riboflavin synthase alpha chain. (219 aa) |
| | ispD | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (246 aa) |
| | Cpar_1336 | PFAM: thioesterase superfamily protein; KEGG: cte:CT1318 ComA2 protein. (149 aa) |
| | Cpar_1337 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cte:CT1320 BchE/P-methylase family protein. (468 aa) |
| | Cpar_1356 | KEGG: cte:CT1436 serine acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein. (273 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa) |
| | Cpar_1424 | KEGG: met:M446_2680 asparagine synthase family amidotransferase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); asparagine synthase family amidotransferase; PFAM: glutamine amidotransferase class-II; asparagine synthase. (592 aa) |
| | Cpar_1438 | TIGRFAM: aconitate hydratase 2; PFAM: aconitate hydratase domain protein; Aconitase B, N-terminal; KEGG: cte:CT0543 aconitate hydratase; Belongs to the aconitase/IPM isomerase family. (854 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | Cpar_1453 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: sun:SUN_2140 acetolactate synthase, large subunit; Belongs to the TPP enzyme family. (598 aa) |
| | Cpar_1454 | PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: mmi:MMAR_2330 short chain dehydrogenase. (221 aa) |
| | Cpar_1455 | PFAM: 3-dehydroquinate synthase; KEGG: rfr:Rfer_1247 3-dehydroquinate synthase. (358 aa) |
| | Cpar_1480 | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cte:CT0390 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (272 aa) |
| | Cpar_1491 | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cte:CT0402 glutamate synthase, small subunit. (490 aa) |
| | Cpar_1492 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: cte:CT0401 glutamate synthase, large subunit. (1534 aa) |
| | gpmA | Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa) |
| | Cpar_1505 | KEGG: cte:CT0372 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (476 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: cte:CT0367 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (440 aa) |
| | ribBA | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (426 aa) |
| | Cpar_1525 | KEGG: cte:CT1596 glycogen phosphorylase family protein; TIGRFAM: alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35. (706 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa) |
| | Cpar_1530 | 6-phosphofructokinase; PFAM: phosphofructokinase; KEGG: cte:CT1603 phosphofructokinase. (401 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (303 aa) |
| | Cpar_1534 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. (404 aa) |
| | tpiA | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (250 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (504 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (361 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa) |
| | Cpar_1570 | KEGG: cte:CT1480 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (286 aa) |
| | mdh | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (310 aa) |
| | Cpar_1600 | PFAM: peptidase M48 Ste24p; KEGG: cte:CT1509 CAAX prenyl protease 1, putative. (413 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (308 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | Cpar_1613 | KEGG: cte:CT1527 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (175 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (296 aa) |
| | Cpar_1655 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa) |
| | fbp | PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: cte:CT0358 fructose-1,6-bisphosphatase. (333 aa) |
| | Cpar_1686 | KEGG: cte:CT0351 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type; Belongs to the monomeric-type IDH family. (741 aa) |
| | Cpar_1687 | KEGG: cte:CT0350 enoyl-[acyl-carrier protein] reductase (NADH). (293 aa) |
| | dxs | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: cte:CT0320 phosphoribosylaminoimidazolecarboxamide formyltransferase. (523 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (200 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (497 aa) |
| | Cpar_1728 | KEGG: cte:CT0309 mannose-6-phosphate isomerase / mannose-1-phosphate guanylyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (469 aa) |
| | Cpar_1729 | TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cte:CT0308 dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (349 aa) |
| | Cpar_1730 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (291 aa) |
| | Cpar_1731 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (185 aa) |
| | Cpar_1732 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | Cpar_1736 | PFAM: hydroxyneurosporene synthase; KEGG: cte:CT0301 hydroxyneurosporene synthase CrtC. (379 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (517 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (332 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | Cpar_1767 | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (268 aa) |
| | Cpar_1774 | PFAM: phosphoglucomutase/phosphomannomutase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: cte:CT0260 phosphoglucomutase/phosphomannomutase family protein. (471 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (357 aa) |
| | Cpar_1778 | PFAM: Polyprenyl synthetase; KEGG: cte:CT0256 isoprenyl synthetase; Belongs to the FPP/GGPP synthase family. (332 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (128 aa) |
| | Cpar_1784 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (390 aa) |
| | Cpar_1790 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: cte:CT0244 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (321 aa) |
| | Cpar_1800 | PFAM: phosphatidate cytidylyltransferase; KEGG: cte:CT0233 phosphatidate cytidylyltransferase; Belongs to the CDS family. (276 aa) |
| | trpB-2 | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (458 aa) |
| | Cpar_1870 | KEGG: cte:CT0173 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. (407 aa) |
| | Cpar_1875 | PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: pvi:Cvib_1597 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (616 aa) |
| | Cpar_1876 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: pvi:Cvib_1598 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (342 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (336 aa) |
| | Cpar_1880 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa) |
| | Cpar_1881 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (694 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (437 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (264 aa) |
| | Cpar_1907 | KEGG: cte:CT2030 aspartate kinase / homoserine dehydrogenase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. (818 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (324 aa) |
| | Cpar_1911 | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. (438 aa) |
| | Cpar_1912 | KEGG: cte:CT2036 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (237 aa) |
| | ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (156 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (351 aa) |
| | Cpar_1916 | CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cte:CT2040 succinate/fumarate oxidoreductase, putative. (283 aa) |
| | Cpar_1917 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: cte:CT2041 succinate/fumarate oxidoreductase, iron-sulfur protein, putative. (345 aa) |
| | Cpar_1918 | KEGG: cte:CT2042 succinate/fumarate oxidoreductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (567 aa) |
| | Cpar_1930 | PFAM: Nucleotidyl transferase; KEGG: cte:CT2056 mannose-1-phosphate guanylyltransferase, putative. (310 aa) |
| | Cpar_1960 | KEGG: cte:CT2088 trehalose synthase; TIGRFAM: trehalose synthase; trehalose synthase-fused possible maltokinase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain. (1109 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa) |
| | Cpar_1992 | PFAM: Prephenate dehydrogenase; KEGG: cte:CT0084 prephenate dehydrogenase. (288 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: cte:CT0092 glycerol-3-phosphate dehydrogenase, NAD-dependent. (338 aa) |
| | plsY | Protein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (232 aa) |
| | purM | KEGG: cte:CT0094 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (329 aa) |
| | Cpar_2003 | KEGG: cte:CT0095 aspartokinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (467 aa) |
| | Cpar_2025 | PFAM: ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cte:CT2266 succinate dehydrogenase, iron-sulfur protein. (257 aa) |
| | Cpar_2026 | KEGG: cte:CT2267 succinate dehydrogenase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (646 aa) |
| | Cpar_2027 | TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: cte:CT2268 succinate dehydrogenase, cytochrome subunit, putative. (222 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (222 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: cte:CT2222 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
