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| Smon_0957 | PFAM: methyltransferase small; Methyltransferase type 12; KEGG: bcz:BCZK0095 methyltransferase. (202 aa) | ||||
| Smon_1495 | KEGG: hpa:HPAG1_0664 hypothetical protein. (115 aa) | ||||
| Smon_1492 | Hypothetical protein. (89 aa) | ||||
| Smon_1480 | TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: bcb:BCB4264_A2176 single-stranded DNA-binding protein. (134 aa) | ||||
| Smon_1474 | KEGG: bcr:BCAH187_A4730 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; SMART: phosphoesterase PHP domain protein. (1056 aa) | ||||
| nusB | NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (133 aa) | ||||
| Smon_1455 | KEGG: prw:PsycPRwf_1121 hypothetical protein. (305 aa) | ||||
| Smon_1453 | PFAM: Eco57I restriction endonuclease; KEGG: ajs:Ajs_0197 Eco57I restriction endonuclease. (348 aa) | ||||
| truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (244 aa) | ||||
| Smon_1431 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (289 aa) | ||||
| Smon_1427 | PFAM: NUDIX hydrolase; KEGG: dps:DP2873 7,8-dihydro-8-oxoguanine- triphosphatase. (151 aa) | ||||
| Smon_1419 | Site-specific DNA-methyltransferase (adenine- specific); PFAM: DNA methylase N-4/N-6 domain protein; KEGG: bcr:BCAH187_A5299 DNA methylase domain protein. (528 aa) | ||||
| tmcAL | Cytidyltransferase-related domain protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (378 aa) | ||||
| Smon_1373 | KEGG: hypothetical protein. (320 aa) | ||||
| tsaD | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (332 aa) | ||||
| Smon_1367 | PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: vvu:VV1_0246 16S rRNA uridine-516 pseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family. (228 aa) | ||||
| dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (378 aa) | ||||
| Smon_1346 | Hypothetical protein. (65 aa) | ||||
| Smon_1329 | DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: UV damage repair protein, ImpB/MucB/SamB family; Belongs to the DNA polymerase type-Y family. (421 aa) | ||||
| gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (660 aa) | ||||
| gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (870 aa) | ||||
| pheS | KEGG: pca:Pcar_1422 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa) | ||||
| pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sat:SYN_01723 phenylalanyl-tRNA synthetase beta chain. (806 aa) | ||||
| Smon_1246 | KEGG: nmn:NMCC_1163 type II restriction enzyme NlaIV. (224 aa) | ||||
| Smon_1245 | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: nmn:NMCC_1162 DNA (cytosine-5-)- methyltransferase. (438 aa) | ||||
| Smon_1240 | KEGG: hypothetical protein. (1348 aa) | ||||
| Smon_1239 | KEGG: viral A-type inclusion protein. (1367 aa) | ||||
| Smon_1238 | PFAM: PP-loop domain protein; KEGG: gur:Gura_0711 PP-loop domain-containing protein; Belongs to the TtcA family. (283 aa) | ||||
| Smon_1234 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_1233 | KEGG: msu:MS0633 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; formate C- acetyltransferase glycine radical. (704 aa) | ||||
| Smon_1202 | PFAM: integrase family protein; KEGG: tdn:Suden_0800 phage integrase. (346 aa) | ||||
| Smon_1198 | PFAM: replication initiator A domain protein; KEGG: bcb:BCB4264_A3622 replication protein, putative. (117 aa) | ||||
| Smon_1193 | PFAM: MobA/MobL protein; KEGG: sbc:SbBS512_D0003 mobilization protein A. (507 aa) | ||||
| Smon_1163 | KEGG: baa:BXB0107 hypothetical protein. (306 aa) | ||||
| Smon_1157 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; SMART: DNA topoisomerase I DNA-binding; Toprim sub domain protein; DNA topoisomerase I ATP-binding; KEGG: vfi:VF_B0046 DNA topoisomerase III. (667 aa) | ||||
| mnmG-2 | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (619 aa) | ||||
| recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (348 aa) | ||||
| recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (689 aa) | ||||
| Smon_1112 | KEGG: rhoptry protein. (313 aa) | ||||
| Smon_1111 | PFAM: protein of unknown function DUF34; KEGG: NIF3-like protein 1, putative. (255 aa) | ||||
| polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (861 aa) | ||||
| Smon_1100 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (297 aa) | ||||
| ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (928 aa) | ||||
| glyQ | KEGG: pca:Pcar_0598 glycyl-tRNA synthetase subunit alpha; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit. (293 aa) | ||||
| glyS | KEGG: bha:BH1371 glycyl-tRNA synthetase subunit beta; TIGRFAM: glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase beta subunit. (668 aa) | ||||
| ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (334 aa) | ||||
| Smon_1088 | Protein of unknown function DUF558; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (233 aa) | ||||
| rsmG | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (231 aa) | ||||
| Smon_1073 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bcy:Bcer98_0829 endonuclease/exonuclease/phosphatase. (597 aa) | ||||
| Smon_1072 | Hypothetical protein; KEGG: Dsec_Top2; GM17008 gene product from transcript GM17008-RA. (215 aa) | ||||
| Smon_1071 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tdn:Suden_1355 site-specific DNA- methyltransferase (adenine-specific); Belongs to the N(4)/N(6)-methyltransferase family. (391 aa) | ||||
| hisS | KEGG: bba:Bd1107 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (414 aa) | ||||
| aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (587 aa) | ||||
| cas9 | CRISPR-associated protein, Csn1 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this [...] (1259 aa) | ||||
| cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (308 aa) | ||||
| cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (104 aa) | ||||
| mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (606 aa) | ||||
| Smon_1038 | PFAM: putative RNA methylase; KEGG: dal:Dalk_2235 hypothetical protein; Belongs to the N(4)/N(6)-methyltransferase family. (249 aa) | ||||
| rlmH | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (154 aa) | ||||
| lysS | TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: gsu:GSU2271 lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (496 aa) | ||||
| queH | Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (248 aa) | ||||
| Smon_1015 | D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. (150 aa) | ||||
| Smon_1013 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0990 | tRNA/rRNA methyltransferase (SpoU); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (172 aa) | ||||
| metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (624 aa) | ||||
| ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (200 aa) | ||||
| Smon_0983 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: sun:SUN_1978 phosphoesterase. (314 aa) | ||||
| Smon_0964 | PFAM: UvrD/REP helicase; KEGG: bcy:Bcer98_0285 ATP-dependent DNA helicase PcrA. (735 aa) | ||||
| dnaA | Chromosomal replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (441 aa) | ||||
| mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (848 aa) | ||||
| serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (422 aa) | ||||
| recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (358 aa) | ||||
| mfd | DEAD/DEAH box helicase domain protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (900 aa) | ||||
| Smon_0058 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0060 | DNA-cytosine methyltransferase; KEGG: rbe:RBE_1392 site-specific DNA methylase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase. (329 aa) | ||||
| Smon_0073 | PFAM: protein of unknown function UPF0079; KEGG: hso:HS_1081 ATPase. (156 aa) | ||||
| Smon_0074 | PFAM: peptidase M22 glycoprotease; KEGG: bha:BH0546 glycoprotein endopeptidase. (223 aa) | ||||
| Smon_0080 | TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: sat:SYN_02529 single-stranded DNA-specific exonuclease. (883 aa) | ||||
| Smon_0085 | PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bce:BC1072 endonuclease/exonuclease/phosphatase family protein. (598 aa) | ||||
| Smon_0088 | Site-specific DNA-methyltransferase (adenine- specific); PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hpa:HPAG1_0048 type II DNA modification enzyme. (369 aa) | ||||
| Smon_0091 | Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (305 aa) | ||||
| rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (109 aa) | ||||
| mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa) | ||||
| Smon_0131 | PFAM: B3/4 domain protein; KEGG: mlo:mll6378 hypothetical protein. (231 aa) | ||||
| Smon_0160 | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: ngk:NGK_2479 modification methylase NgoPII. (328 aa) | ||||
| Smon_0162 | KEGG: hypothetical protein. (1346 aa) | ||||
| Smon_0167 | KEGG: rhoptry protein. (1336 aa) | ||||
| Smon_0168 | KEGG: 235 kDa rhoptry protein. (874 aa) | ||||
| gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (492 aa) | ||||
| Smon_0218 | PFAM: transposase IS200-family protein; KEGG: hpy:HP1008 IS200 insertion sequence from SARA17. (146 aa) | ||||
| valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (879 aa) | ||||
| rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (416 aa) | ||||
| Smon_0263 | KEGG: hypothetical protein. (200 aa) | ||||
| Smon_0266 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0272 | KEGG: cjr:CJE0603 hypothetical protein; Belongs to the methyltransferase superfamily. (203 aa) | ||||
| Smon_0289 | Site-specific DNA-methyltransferase (adenine- specific); PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: hpg:HPG27_1422 type II methylase. (337 aa) | ||||
| Smon_0298 | KEGG: 235 kDa rhoptry protein. (1308 aa) | ||||
| miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (296 aa) | ||||
| proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (574 aa) | ||||
| polC | DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1465 aa) | ||||
| argS | KEGG: apa:APP7_0039 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (572 aa) | ||||
| rnhB | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (199 aa) | ||||
| rpsK | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (127 aa) | ||||
| rpoA | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (322 aa) | ||||
| Smon_0348 | TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: bha:BH0113 tRNA/rRNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (232 aa) | ||||
| leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: gme:Gmet_2300 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (865 aa) | ||||
| Smon_0352 | PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: conserved hypothetical protein, putative exonuclease. (426 aa) | ||||
| Smon_0354 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (542 aa) | ||||
| Smon_0358 | PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: bha:BH1529 integrase/recombinase; Belongs to the 'phage' integrase family. (287 aa) | ||||
| Smon_0366 | PFAM: DNA polymerase III delta; KEGG: conserved hypothetical protein. (295 aa) | ||||
| gatC | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (98 aa) | ||||
| gatB | glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (475 aa) | ||||
| priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (643 aa) | ||||
| fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (308 aa) | ||||
| thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (633 aa) | ||||
| Smon_0394 | TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: wsu:WS1405 methyltransferase. (345 aa) | ||||
| pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (732 aa) | ||||
| trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (324 aa) | ||||
| recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (195 aa) | ||||
| Smon_0417 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (142 aa) | ||||
| alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (865 aa) | ||||
| asnS | TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: bba:Bd1054 asparaginyl-tRNA synthetase. (460 aa) | ||||
| topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (768 aa) | ||||
| Smon_0435 | PFAM: integrase family protein; integrase domain protein SAM domain protein; KEGG: bcb:BCB4264_A4199 integrase/recombinase XerD; Belongs to the 'phage' integrase family. (299 aa) | ||||
| Smon_0439 | Hypothetical protein; KEGG: cco:CCC13826_1620 uracil-DNA glycosylase superfamily protein. (188 aa) | ||||
| Smon_0452 | Hypothetical protein. (338 aa) | ||||
| rpoB | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1152 aa) | ||||
| rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1323 aa) | ||||
| Smon_0484 | Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (61 aa) | ||||
| dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (595 aa) | ||||
| sigA | RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (379 aa) | ||||
| Smon_0493 | KEGG: hypothetical protein. (221 aa) | ||||
| Smon_0494 | KEGG: hypothetical protein. (618 aa) | ||||
| Smon_0495 | PFAM: UvrD/REP helicase; KEGG: abu:Abu_2069 ATP-dependent DNA helicase UvrD. (981 aa) | ||||
| nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (215 aa) | ||||
| uvrC | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (588 aa) | ||||
| rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (273 aa) | ||||
| nusG | NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (190 aa) | ||||
| rplA | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (235 aa) | ||||
| Smon_0523 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| ybeY | Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (154 aa) | ||||
| Smon_0535 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0541 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (694 aa) | ||||
| Smon_0542 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (333 aa) | ||||
| Smon_0550 | Pseudouridylate synthase-like protein; KEGG: nis:NIS_1108 tRNA pseudouridine synthase A; Belongs to the tRNA pseudouridine synthase TruA family. (211 aa) | ||||
| psuG | Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (304 aa) | ||||
| Smon_0558 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0561 | PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: bha:BH3112 rRNA methylase. (254 aa) | ||||
| Smon_0565 | PFAM: heat shock protein DnaJ domain protein; KEGG: abu:Abu_1033 DnaJ domain-containing protein. (163 aa) | ||||
| Smon_0567 | TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: bsu:BSU00390 hypothetical protein. (256 aa) | ||||
| Smon_0571 | RNA methyltransferase, TrmA family; KEGG: bha:BH0687 RNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; deoxyribonuclease/rho motif-related TRAM; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (473 aa) | ||||
| Smon_0577 | RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (280 aa) | ||||
| Smon_0578 | KEGG: ecn:Ecaj_0815 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain; SMART: DNA polymerase III beta chain. (371 aa) | ||||
| Smon_0585 | PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein. (207 aa) | ||||
| rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (231 aa) | ||||
| rlmN | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (353 aa) | ||||
| trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (231 aa) | ||||
| queA | S-adenosylmethionine/tRNA-ribosyltransferase-iso merase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (342 aa) | ||||
| Smon_0618 | TIGRFAM: methyltransferase; PFAM: Protein of unknown function methylase putative; KEGG: bha:BH2590 hypothetical protein. (183 aa) | ||||
| xseB | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (65 aa) | ||||
| tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. (397 aa) | ||||
| mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (779 aa) | ||||
| cysS | TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia DALR; KEGG: bcb:BCB4264_A0110 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (457 aa) | ||||
| Smon_0637 | KEGG: pub:SAR11_1000 DNA polymerase III. (294 aa) | ||||
| ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (200 aa) | ||||
| Smon_0641 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (938 aa) | ||||
| Smon_0643 | TIGRFAM: RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; KEGG: RNA methyltransferase; K00599; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (466 aa) | ||||
| Smon_0646 | PFAM: replication initiator A domain protein. (251 aa) | ||||
| Smon_0654 | RNA-directed DNA polymerase. (544 aa) | ||||
| Smon_0657 | PFAM: N-6 DNA methylase; KEGG: dde:Dde_1861 type I restriction-modification system specificity subunit. (725 aa) | ||||
| Smon_0658 | PFAM: restriction modification system DNA specificity domain; KEGG: dde:Dde_1860 type I restriction enzyme, S subunit. (473 aa) | ||||
| Smon_0659 | PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; KEGG: dde:Dde_1859 DEAD/DEAH box helicase-like. (969 aa) | ||||
| Smon_0663 | Hypothetical protein; KEGG: hsm:HSM_1190 relaxase/mobilization nuclease family protein. (364 aa) | ||||
| Smon_0664 | PFAM: RNA-directed DNA polymerase (Reverse transcriptase); intron maturase type II; KEGG: bpt:Bpet4285 mobile mitochondrial group II intron of COX1 which IS involved in pre-mRNA splicing and in deletion of introns from mitochondrial DNA. (605 aa) | ||||
| Smon_0689 | Hypothetical protein. (1084 aa) | ||||
| Smon_0700 | PFAM: protein of unknown function UPF0044; KEGG: dol:Dole_1077 hypothetical protein. (112 aa) | ||||
| rsmI | Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (226 aa) | ||||
| tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (402 aa) | ||||
| rnr | VacB and RNase II family 3'-5' exoribonuclease; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (619 aa) | ||||
| Smon_0716 | DNA-(apurinic or apyrimidinic site) lyase; KEGG: rec:RHECIAT_PB0000014 putative N- glycosylase/DNA lyase protein, HhH-GPD family; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein. (217 aa) | ||||
| Smon_0718 | PFAM: SirA family protein; KEGG: sgl:SG1742 hypothetical protein; Belongs to the sulfur carrier protein TusA family. (76 aa) | ||||
| Smon_0721 | Hypothetical protein; Belongs to the sulfur carrier protein TusA family. (70 aa) | ||||
| Smon_0731 | PFAM: PP-loop domain protein; KEGG: pca:Pcar_0671 PP family ATPase; Belongs to the TtcA family. (286 aa) | ||||
| truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (285 aa) | ||||
| Smon_0739 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (463 aa) | ||||
| dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (455 aa) | ||||
| Smon_0744 | PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: bcy:Bcer98_3369 pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family. (230 aa) | ||||
| tdk | PFAM: thymidine kinase; KEGG: bsu:BSU37060 thymidine kinase. (358 aa) | ||||
| Smon_0754 | PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: abu:Abu_1113 hypothetical protein. (205 aa) | ||||
| Smon_0768 | PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: bsu:BSU27620 hypothetical protein. (557 aa) | ||||
| rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (124 aa) | ||||
| nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (362 aa) | ||||
| Smon_0775 | PFAM: protein of unknown function DUF147; KEGG: bsu:BSU00880 DNA integrity scanning protein DisA; Belongs to the DisA family. (349 aa) | ||||
| radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (448 aa) | ||||
| rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (233 aa) | ||||
| miaB | RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (438 aa) | ||||
| Smon_0785 | KEGG: bcb:BCB4264_A3839 exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase. (251 aa) | ||||
| rsmH | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (309 aa) | ||||
| Smon_0790 | KEGG: rhoptry protein. (1185 aa) | ||||
| Smon_0792 | PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; KEGG: cha:CHAB381_0798 DNA-binding protein HU 1 (DNA-binding protein II) (HB); Belongs to the bacterial histone-like protein family. (93 aa) | ||||
| Smon_0796 | TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S- methyltransferase DNA binding; KEGG: eca:ECA2454 methylated DNA--protein-cysteine methyltransferase. (173 aa) | ||||
| Smon_0810 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0813 | Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (317 aa) | ||||
| Smon_0815 | PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: nis:NIS_0066 recombination factor protein RarA. (395 aa) | ||||
| Smon_0817 | PFAM: protein of unknown function DUF195; KEGG: cps:CPS_3589 hypothetical protein. (359 aa) | ||||
| thiI | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (394 aa) | ||||
| tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (387 aa) | ||||
| Smon_0824 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0837 | Recombinational DNA repair protein (RecF pathway)-like protein; Involved in DNA repair and RecF pathway recombination. (215 aa) | ||||
| trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (245 aa) | ||||
| rimM | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (163 aa) | ||||
| Smon_0851 | KEGG: gsu:GSU0647 hypothetical protein. (187 aa) | ||||
| Smon_0852 | PFAM: Polynucleotide adenylyltransferase region; NUDIX hydrolase; KEGG: hac:Hac_0768 poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (577 aa) | ||||
| Smon_0853 | PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: bcy:Bcer98_2517 sun protein. (422 aa) | ||||
| mnmA | tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (359 aa) | ||||
| Smon_0857 | PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: pap:PSPA7_3451 hypothetical protein. (154 aa) | ||||
| Smon_0859 | Hypothetical protein; KEGG: vsa:pVSAL840_45 transposase. (407 aa) | ||||
| Smon_0865 | PFAM: integrase family protein; KEGG: tdn:Suden_1743 phage integrase; Belongs to the 'phage' integrase family. (353 aa) | ||||
| Smon_0866 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; SMART: DNA topoisomerase I DNA-binding; Toprim sub domain protein; DNA topoisomerase I ATP-binding; KEGG: vfi:VF_B0046 DNA topoisomerase III. (663 aa) | ||||
| Smon_0870 | KEGG: baa:BXB0107 hypothetical protein. (311 aa) | ||||
| Smon_0880 | Virulence-associated protein D (VapD) conserved region; Cleaves ssRNA, mostly between U:A. Belongs to the VapD ribonuclease family. (95 aa) | ||||
| Smon_0900 | PFAM: MobA/MobL protein; KEGG: sbc:SbBS512_D0003 mobilization protein A. (504 aa) | ||||
| Smon_0907 | PFAM: replication initiator A domain protein; KEGG: bcb:BCB4264_A3622 replication protein, putative. (116 aa) | ||||
| Smon_0910 | PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: bcu:BCAH820_0476 DNA-binding protein. (130 aa) | ||||
| Smon_0912 | PFAM: integrase family protein; KEGG: bcy:Bcer98_2627 phage integrase family protein; Belongs to the 'phage' integrase family. (353 aa) | ||||
| smc | SMC domain protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1180 aa) | ||||
| xseA | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (442 aa) | ||||
| uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa) | ||||
| Smon_0923 | PFAM: O-methyltransferase family 3; KEGG: bcb:BCB4264_A4503 O-methyltransferase family protein. (209 aa) | ||||
| Smon_0929 | PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: bcc:BCc_214 RluC; Belongs to the pseudouridine synthase RluA family. (280 aa) | ||||
| rny | RNA binding metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. (530 aa) | ||||
| ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (675 aa) | ||||
| Smon_0949 | PFAM: Uracil-DNA glycosylase superfamily; KEGG: uracil-DNA glycosylase; K03648 uracil-DNA glycosylase; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (537 aa) | ||||
| rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (619 aa) | ||||
| mnmG | Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (635 aa) | ||||