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| | Huta_0332 | PFAM: PHP domain protein; KEGG: nth:Nther_1995 histidinol phosphate phosphatase HisJ family. (257 aa) |
| | Huta_2790 | PFAM: translation initiation factor 2, alpha subunit; RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: hma:rrnAC3512 translation initiation factor IF-2 subunit alpha. (266 aa) |
| | rps27e | PFAM: Ribosomal protein S27E; KEGG: hsl:OE1820R ribosomal protein S27.eR. (57 aa) |
| | rpl44e | Ribosomal protein L44E; Binds to the 23S rRNA. (93 aa) |
| | Huta_2786 | KEGG: hma:rrnAC3517 hypothetical protein. (783 aa) |
| | dbh | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (417 aa) |
| | priS | DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (386 aa) |
| | smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1188 aa) |
| | gatB | glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (495 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (844 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (434 aa) |
| | Huta_2702 | DNA-(apurinic or apyrimidinic site) lyase; KEGG: hma:rrnAC1908 endonuclease III; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein. (274 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (484 aa) |
| | Huta_2680 | TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: nph:NP3590A IS1341-type transposase. (413 aa) |
| | infB | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (602 aa) |
| | rpl37ae | Ribosomal protein L37a; Binds to the 23S rRNA. (94 aa) |
| | psmA | Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (245 aa) |
| | Huta_2662 | Aminoacyl-tRNA hydrolase; PFAM: protein of unknown function UPF0099; KEGG: hma:rrnAC1774 peptidyl-tRNA hydrolase. (112 aa) |
| | gatE | aspartyl-tRNA(Asn) amidotransferase, B subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (631 aa) |
| | Huta_2656 | TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: hma:rrnAC0018 RNA methyltransferase. (237 aa) |
| | uvrC | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (579 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (693 aa) |
| | Huta_2595 | Cryptochrome, DASH family; KEGG: nph:NP3456A deoxyribodipyrimidine photolyase; TIGRFAM: cryptochrome, DASH family; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein. (478 aa) |
| | eif5a | Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (124 aa) |
| | Huta_2561 | TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; putative transposase IS891/IS1136/IS1341 family; KEGG: nph:NP5060A IS1341-type transposase. (440 aa) |
| | Huta_2560 | PFAM: protein-L-isoaspartate(D-aspartate) O- methyltransferase; KEGG: hma:rrnAC2256 protein-L-isoaspartate O- methyltransferase 2. (244 aa) |
| | pcm | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (225 aa) |
| | Huta_2558 | KEGG: hma:rrnAC2259 hypothetical protein. (215 aa) |
| | rpl10e | PFAM: ribosomal protein L16; KEGG: hma:rrnAC2357 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family. (176 aa) |
| | Huta_2534 | TIGRFAM: translation initiation factor SUI1; PFAM: translation initiation factor SUI1; KEGG: hma:rrnAC2445 translation initiation factor SUI1; Belongs to the SUI1 family. (97 aa) |
| | Huta_2530 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: hma:rrnAC0542 methyltransferase. (214 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (345 aa) |
| | rps13 | Ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (176 aa) |
| | rps4 | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (169 aa) |
| | rps11 | Ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (128 aa) |
| | rpl18e | PFAM: ribosomal protein L15; KEGG: nph:NP2836A 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family. (116 aa) |
| | rpl13 | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (146 aa) |
| | rps9 | PFAM: ribosomal protein S9; KEGG: hma:rrnAC0066 30S ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (132 aa) |
| | rps2 | TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; KEGG: hma:rrnAC0070 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (267 aa) |
| | fen | XPG I domain protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...] (326 aa) |
| | Huta_2491 | TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; KEGG: nph:NP1856A IS1341-type transposase. (349 aa) |
| | Huta_2469 | KEGG: nph:NP0818A hypothetical protein. (249 aa) |
| | Huta_2462 | KEGG: afu:AF0817 hypothetical protein. (652 aa) |
| | nfi | Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (269 aa) |
| | Huta_2447 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; KEGG: hma:rrnAC0669 DNA polymerase IV. (580 aa) |
| | Huta_2431 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hma:rrnAC1686 hypothetical protein. (224 aa) |
| | nfo | Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (276 aa) |
| | Huta_2391 | PFAM: Fibronectin type III domain protein; glycoside hydrolase family 10; SMART: Fibronectin type III domain protein; glycoside hydrolase family 10; KEGG: sus:Acid_2816 glycoside hydrolase family protein. (748 aa) |
| | rpl15e | PFAM: Ribosomal protein L15e; KEGG: nph:NP0246A 50S ribosomal protein L15e; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa) |
| | rps7 | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (202 aa) |
| | rps12 | Ribosomal protein S23 (S12); With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (685 aa) |
| | Huta_2353 | PFAM: KaiA binding; Circadian clock protein KaiC central region; KEGG: rca:Rcas_0671 putative circadian clock protein, KaiC. (489 aa) |
| | Huta_2338 | Ribonucleoside-diphosphate reductase, alpha subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (815 aa) |
| | rpl15 | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (161 aa) |
| | rpl30 | TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: nph:NP4896A 50S ribosomal protein L30P. (154 aa) |
| | rps5 | Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (210 aa) |
| | rpl18 | Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (187 aa) |
| | rpl19e | Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (148 aa) |
| | rpl32e | PFAM: Ribosomal protein L32e; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: hma:rrnAC1595 50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family. (335 aa) |
| | rpl6 | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) |
| | rps8 | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rps14 | Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles. (64 aa) |
| | rpl5 | Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (176 aa) |
| | rps4e | PFAM: Ribosomal protein S4E, central domain protein; Ribosomal protein S4E domain protein; KEGG: hma:rrnAC1600 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (286 aa) |
| | rpl24 | Ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (119 aa) |
| | rpl14 | Ribosomal protein L14b/L23e; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa) |
| | rps17 | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (108 aa) |
| | rpl29 | TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; KEGG: hma:rrnAC1604 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (68 aa) |
| | rps3 | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (326 aa) |
| | rpl22 | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (156 aa) |
| | rps19p | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (141 aa) |
| | rpl2 | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (242 aa) |
| | rpl23 | Ribosomal protein L25/L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (87 aa) |
| | rpl4 | Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. (247 aa) |
| | rpl3 | Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (338 aa) |
| | Huta_2271 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: hma:rrnAC3371 ATP-dependant helicase. (789 aa) |
| | Huta_2247 | PFAM: nucleic acid binding OB-fold tRNA/helicase- type; KEGG: hma:rrnAC2302 replication factor A. (486 aa) |
| | Huta_2215 | PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: hma:rrnAC2818 cell division protein FtsH; Belongs to the AAA ATPase family. (451 aa) |
| | eif2g | Protein synthesis factor GTP-binding; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (411 aa) |
| | spt4 | DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family. (65 aa) |
| | Huta_2203 | PFAM: transposase IS200-family protein; KEGG: hma:pNG5127 transposase. (140 aa) |
| | Huta_2202 | TIGRFAM: transposase, IS605 OrfB family; PFAM: putative transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: hma:pNG5128 transposase. (417 aa) |
| | Huta_2167 | Transcriptional regulator, XRE family; PFAM: MCM family protein; helix-turn-helix domain protein; SMART: MCM family protein; Hedgehog/intein hint domain protein; helix-turn-helix domain protein; KEGG: hma:rrnAC2762 cell division control protein 21. (1412 aa) |
| | Huta_2146 | TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: mth:MTH1789 dTDP-glucose 4,6-dehydratase. (308 aa) |
| | Huta_2145 | PFAM: dTDP-4-dehydrorhamnose reductase; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: sru:SRU_1854 dTDP-4-dehydrorhamnose reductase. (297 aa) |
| | Huta_2143 | TIGRFAM: glucose-1-phosphate thymidyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; KEGG: mst:Msp_1102 dTDP-glucose pyrophosphorylase. (357 aa) |
| | Huta_2142 | KEGG: mem:Memar_0185 dTDP-4-dehydrorhamnose 3,5- epimerase. (155 aa) |
| | Huta_2138 | PFAM: glycosyl transferase family 2; KEGG: tpd:Teth39_1630 glycosyl transferase family protein. (311 aa) |
| | Huta_2136 | PFAM: glycosyl transferase group 1; KEGG: mth:MTH335 galactosyl-transferase RfpB related protein. (362 aa) |
| | Huta_2135 | PFAM: sulfatase; KEGG: hwa:HQ3540A arylsulfatase. (429 aa) |
| | Huta_2134 | PFAM: glycosyl transferase group 1; KEGG: hwa:HQ3544A hexosyltransferase; glycosyltransferase. (370 aa) |
| | Huta_2131 | PFAM: Laminin G sub domain 2; SMART: LamG domain protein jellyroll fold domain protein; KEGG: hma:rrnAC3242 hypothetical protein. (981 aa) |
| | hel308 | DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (988 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (582 aa) |
| | Huta_2059 | Hypothetical protein; KEGG: nph:NP1516A chromosome segregation protein. (403 aa) |
| | rnj | Beta-lactamase domain protein; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa) |
| | argS | KEGG: hma:rrnAC3169 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (583 aa) |
| | prf1 | Peptide chain release factor eRF/aRF, subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (417 aa) |
| | Huta_1989 | PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hma:rrnAC1686 hypothetical protein. (222 aa) |
| | hisS | KEGG: nph:NP5044A histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (434 aa) |
| | rps19e | Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (153 aa) |
| | lysS | KEGG: hma:rrnAC3173 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase class 1c; Belongs to the class-I aminoacyl-tRNA synthetase family. (546 aa) |
| | Huta_1972 | Protein of unknown function DUF650; Involved in DNA damage repair. (426 aa) |
| | Huta_1957 | PFAM: Replication factor C; SMART: AAA ATPase; KEGG: hma:rrnAC2487 replication factor C small subunit 2. (336 aa) |
| | rps24e | PFAM: Ribosomal protein S24e; KEGG: hma:rrnAC2488 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (103 aa) |
| | rps27ae | PFAM: Ribosomal protein S27a; KEGG: nph:NP5072A 30S ribosomal protein S27ae; Belongs to the eukaryotic ribosomal protein eS31 family. (44 aa) |
| | Huta_1952 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: nph:NP5144A helicase. (699 aa) |
| | Huta_1933 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: hma:rrnAC2920 hypothetical protein. (263 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (926 aa) |
| | rfcS | Replication factor C; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (326 aa) |
| | Huta_1916 | KEGG: hsl:OE5350R hypothetical protein. (1430 aa) |
| | Huta_1891 | PFAM: DNA polymerase B region; KEGG: hsl:OE6036F putative DNA-directed DNA polymerase type II. (768 aa) |
| | Huta_1889 | KEGG: hma:pNG6179 hypothetical protein. (312 aa) |
| | Huta_1887 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (336 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1068 aa) |
| | Huta_1820 | PFAM: protein of unknown function UPF0066; KEGG: chy:CHY_0500 hypothetical protein. (162 aa) |
| | Huta_1815 | KEGG: tte:TTE1855 hypothetical protein. (253 aa) |
| | rlmE | Ribosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (256 aa) |
| | Huta_1768 | TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: hma:rrnAC2796 uracil DNA glycosylase superfamily protein. (194 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (451 aa) |
| | Huta_1730 | PFAM: UvrD/REP helicase; nucleic acid binding OB- fold tRNA/helicase-type; KEGG: nph:NP3864A helicase. (916 aa) |
| | Huta_1725 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (339 aa) |
| | Huta_1711 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: hwa:HQ3274A helicase. (1764 aa) |
| | Huta_1707 | KEGG: nph:NP3874A restriction/modification enzyme. (1343 aa) |
| | Huta_1703 | McrBC 5-methylcytosine restriction system component-like protein; KEGG: hma:rrnAC2393 hypothetical protein. (421 aa) |
| | Huta_1694 | KEGG: hma:pNG6120 hypothetical protein. (282 aa) |
| | Huta_1680 | PFAM: Non-histone chromosomal MC1 family protein; KEGG: hma:rrnAC2971 hypothetical protein. (103 aa) |
| | pheT | KEGG: hma:rrnAC2967 phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5; B3/4 domain protein. (576 aa) |
| | Huta_1675 | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; KEGG: nph:NP0696A phenylalanyl-tRNA synthetase subunit alpha. (501 aa) |
| | trpS | Tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). (537 aa) |
| | Huta_1659 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; helicase domain protein; KEGG: hma:rrnAC2961 pre-mRNA splicing helicase. (800 aa) |
| | hjc | Resolvase, Holliday junction-type; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products; Belongs to the Holliday junction resolvase Hjc family. (172 aa) |
| | priL | DNA primase, large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (361 aa) |
| | pcn | Proliferating cell nuclear antigen, PCNA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (247 aa) |
| | Huta_1638 | TIGRFAM: leucyl-tRNA synthetase; KEGG: hma:rrnAC2947 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (889 aa) |
| | Huta_1629 | PFAM: nucleic acid binding OB-fold tRNA/helicase- type; KEGG: hma:rrnAC2744 replication factor A. (311 aa) |
| | polC | DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1193 aa) |
| | Huta_1613 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (591 aa) |
| | polB | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (537 aa) |
| | eif1a-2 | Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (95 aa) |
| | Huta_1601 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: csc:Csac_0774 anaerobic ribonucleoside triphosphate reductase. (706 aa) |
| | Huta_1552 | PFAM: PilT protein domain protein; KEGG: hsl:OE1124R hypothetical protein. (151 aa) |
| | trm1 | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (374 aa) |
| | Huta_1488 | KEGG: hma:rrnAC2701 glycyl-tRNA synthetase; TIGRFAM: glycyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (586 aa) |
| | Huta_1486 | PFAM: helicase domain protein; ERCC4 domain protein; helix-hairpin-helix motif; DEAD/DEAH box helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; helicase domain protein; Helix-hairpin-helix DNA-binding class 1; KEGG: hma:rrnAC2704 Hef nuclease. (833 aa) |
| | Huta_1478 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hwa:HQ3463A phosphatase-like protein. (224 aa) |
| | Huta_1477 | Endo-1,4-beta-xylanase; KEGG: tfu:Tfu_2791 xylanase; PFAM: glycoside hydrolase family 10; SMART: glycoside hydrolase family 10. (317 aa) |
| | Huta_1453 | TIGRFAM: CRISPR-associated protein, Csh2 family; CRISPR-associated protein, CT1132 family; PFAM: CRISPR-associated protein TM1801; KEGG: hma:pNG4049 CRISPR-associated protein. (359 aa) |
| | cas1 | CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (330 aa) |
| | cas2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa) |
| | Huta_1443 | PFAM: UvrD/REP helicase; KEGG: hma:rrnAC2267 repair helicase. (613 aa) |
| | Huta_1431 | TIGRFAM: ATP synthase H subunit; KEGG: hma:rrnAC3152 vacuolar (H+)-ATPase G subunit. (110 aa) |
| | Huta_1399 | PFAM: integrase family protein; KEGG: mbu:Mbur_2299 phage integrase. (430 aa) |
| | Huta_1398 | PFAM: initiation factor 2B related; NUDIX hydrolase; KEGG: hma:rrnAC2247 translation initiation factor eIF-2B alpha subunit; Belongs to the eIF-2B alpha/beta/delta subunits family. (414 aa) |
| | rpl18a | PFAM: Ribosomal LX protein; KEGG: nph:NP0186A 50S ribosomal protein LX. (57 aa) |
| | rpl40e | KEGG: hma:rrnAC2802 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa) |
| | Huta_1290 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1039 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (348 aa) |
| | Huta_1249 | PFAM: putative RNA methylase; Methyltransferase type 11; KEGG: hma:rrnAC2834 putative RNA methylase. (343 aa) |
| | Huta_1188 | PFAM: glycosyl transferase family 2; conserved hypothetical protein; KEGG: hma:rrnAC1873 dolichol-P-glucose synthetase. (606 aa) |
| | Huta_1185 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: hma:rrnAC1876 CtaG modification methylase. (344 aa) |
| | Huta_1160 | 26S proteasome subunit P45 family; KEGG: hma:rrnAC3190 proteasome-activating nucleotidase; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family. (407 aa) |
| | Huta_1155 | PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain protein; elongation factor Tu domain 2 protein; KEGG: hma:rrnAC1619 GTP-binding protein-like. (545 aa) |
| | Huta_1130 | PFAM: glycosyl transferase group 1; KEGG: hsl:OE1112R putative glycosyltransferase, type 1. (357 aa) |
| | Huta_1126 | PFAM: glycosyl transferase group 1; KEGG: rrs:RoseRS_4438 glycosyl transferase, group 1. (360 aa) |
| | Huta_1124 | PFAM: glycosyl transferase group 1; KEGG: neu:NE2269 glycosyl transferase group 1. (371 aa) |
| | Huta_1121 | PFAM: glycosyl transferase group 1; KEGG: chu:CHU_0890 A-glycosyltransferase. (386 aa) |
| | Huta_1112 | KEGG: tma:TM0070 endo-1,4-beta-xylanase B; PFAM: glycoside hydrolase family 10; SMART: glycoside hydrolase family 10. (328 aa) |
| | trmY | Protein of unknown function DUF358; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (198 aa) |
| | Huta_1077 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (401 aa) |
| | Huta_1074 | PFAM: transposase IS4 family protein; KEGG: hma:pNG7397 putative transposase. (273 aa) |
| | Huta_1070 | PFAM: sulfatase; KEGG: hma:rrnAC0426 putative sulfatase. (463 aa) |
| | Huta_1065 | Glycosyltransferase-like protein; KEGG: mba:Mbar_A1129 glycosyltransferase. (311 aa) |
| | Huta_1055 | Orc1/cdc6 family replication initiation protein; Involved in regulation of DNA replication. (375 aa) |
| | Huta_1050 | PFAM: glycosyl transferase group 1; KEGG: hma:rrnAC1958 LPS glycosyltransferase. (349 aa) |
| | mutS2 | DNA mismatch repair protein MutS domain protein; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (664 aa) |
| | Huta_1018 | PFAM: protein of unknown function UPF0066; KEGG: sfu:Sfum_0270 protein of unknown function UPF0066. (171 aa) |
| | taw2 | Methyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (365 aa) |
| | rpl39e | PFAM: Ribosomal protein L39e; KEGG: hsl:OE4460R ribosomal protein L39.eR; Belongs to the eukaryotic ribosomal protein eL39 family. (50 aa) |
| | rpl31e | PFAM: Ribosomal protein L31e; KEGG: hwa:HQ3423A 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family. (92 aa) |
| | eif6 | Translation initiation factor eIF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (221 aa) |
| | Huta_0996 | TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; KEGG: nph:NP4546A IS1341-type transposase. (409 aa) |
| | glmS-2 | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa) |
| | Huta_0988 | PFAM: glycoside hydrolase family 10; SMART: glycoside hydrolase family 10; KEGG: sde:Sde_0323 TonB-like. (975 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (234 aa) |
| | Huta_0941 | MCP methyltransferase, CheR-type; KEGG: hma:rrnAC2206 chemotaxis protein methyltransferase CheR; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type. (271 aa) |
| | rps6e | PFAM: Ribosomal protein S6e; KEGG: hma:rrnAC2212 30S ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family. (127 aa) |
| | rps8e | TIGRFAM: ribosomal protein S8e; PFAM: Ribosomal protein S8E; KEGG: hma:rrnAC1511 30S ribosomal protein S8e. (123 aa) |
| | radB | DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. (227 aa) |
| | spt5 | NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (145 aa) |
| | rps10-2 | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (121 aa) |
| | Huta_0823 | PFAM: 8-oxoguanine DNA glycosylase domain protein; HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: hma:rrnAC1166 8-oxoguanine DNA glycosylase. (307 aa) |
| | Huta_0820 | PFAM: Translation initiation factor IF2/IF5; SMART: Translation initiation factor IF2/IF5; KEGG: hma:rrnAC1124 translation initiation factor IF-2 subunit beta. (129 aa) |
| | Huta_0816 | PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: hma:rrnAC0839 chaperone protein DnaJ. (266 aa) |
| | tuf | Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (423 aa) |
| | rps10 | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | Huta_0789 | PFAM: integrase domain protein SAM domain protein; integrase family protein; KEGG: hma:rrnAC2382 phage integrase. (351 aa) |
| | Huta_0779 | PFAM: Translation initiation factor IF2/IF5; deoxyribonuclease/rho motif-related TRAM; SMART: Translation initiation factor IF2/IF5; KEGG: hma:rrnAC0138 translation initiation factor IF-2 subunit beta. (204 aa) |
| | Huta_0778 | PFAM: glycosyl transferase group 1; KEGG: hma:rrnAC1350 putative sugar transferase. (333 aa) |
| | eif1a | S1 IF1 family protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (94 aa) |
| | rps17e | KEGG: hma:rrnAC0055 30S ribosomal protein S17e; Belongs to the eukaryotic ribosomal protein eS17 family. (63 aa) |
| | rpl24e | Ribosomal protein L24E; Binds to the 23S rRNA. (139 aa) |
| | rps28e | PFAM: Ribosomal protein S28e; KEGG: nph:NP3662A 30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (75 aa) |
| | rpl7ae | Ribosomal protein L7Ae/L30e/S12e/Gadd45; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa) |
| | Huta_0733 | PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: hsl:OE2276F phosphotransferase domain- containing protein. (228 aa) |
| | rps15 | PFAM: ribosomal protein S15; Ribosomal S13S15 domain protein; KEGG: hma:rrnAC1426 30S ribosomal protein S15P. (151 aa) |
| | rps3ae | PFAM: ribosomal protein S3Ae; KEGG: hma:rrnAC1429 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (206 aa) |
| | rpl37e | Ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (57 aa) |
| | ef1b | Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (88 aa) |
| | rpl21e | PFAM: Ribosomal protein L21e; KEGG: hma:rrnAC0260 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family. (98 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (292 aa) |
| | Huta_0620 | TIGRFAM: methylase; PFAM: Methyltransferase type 11; methyltransferase small; Methyltransferase type 12; KEGG: hma:rrnAC0256 protporphyrinogen oxidase. (204 aa) |
| | Huta_0618 | PFAM: Threonyl/alanyl tRNA synthetase SAD; KEGG: sru:SRU_1141 alanyl-tRNA synthetase. (265 aa) |
| | Huta_0603 | PFAM: glycosyl transferase group 1; KEGG: hma:rrnAC0179 LPS biosynthesis protein. (352 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (228 aa) |
| | Huta_0551 | SMART: DNA mismatch repair protein MutS domain protein; KEGG: hma:rrnAC1144 DNA mismatch repair protein. (583 aa) |
| | Huta_0549 | PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: hma:rrnAC1139 ATP-dependent helicase. (943 aa) |
| | Huta_0544 | PFAM: nucleic acid binding OB-fold tRNA/helicase- type; KEGG: hma:rrnAC1133 replication factor A. (423 aa) |
| | Huta_0538 | PFAM: sulfatase; KEGG: hma:rrnAC0428 putative sulfatase. (451 aa) |
| | Huta_0536 | PFAM: sulfatase; type I phosphodiesterase/nucleotide pyrophosphatase; KEGG: hma:rrnAC0426 putative sulfatase. (473 aa) |
| | Huta_0534 | TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; KEGG: nph:NP1696A IS1341-type transposase. (409 aa) |
| | Huta_0493 | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. (915 aa) |
| | Huta_0480 | PFAM: glycosyl transferase family 2; KEGG: mem:Memar_0960 glycosyl transferase family protein. (410 aa) |
| | Huta_0475 | PFAM: sulfatase; KEGG: hwa:HQ3543A arylsulfatase. (434 aa) |
| | Huta_0474 | Glycosyltransferase-like protein; KEGG: mem:Memar_0693 glycosyl transferase, group 1. (310 aa) |
| | glmS | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (865 aa) |
| | Huta_0455 | PFAM: DNA replication factor Dna2; KEGG: hma:rrnAC0954 DNA helicase. (902 aa) |
| | thrS | TIGRFAM: threonyl-tRNA synthetase; PFAM: Threonyl-tRNA synthetase editing domain protein; tRNA synthetase class II (G H P and S); Anticodon- binding domain protein; KEGG: mem:Memar_0766 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (620 aa) |
| | Huta_0387 | Transcriptional regulator, MarR family; PFAM: regulatory protein MarR; KEGG: hma:rrnAC0842 transcription repressor CinR. (116 aa) |
| | Huta_0375 | PFAM: DNA polymerase B region; DNA polymerase B exonuclease; SMART: DNA-directed DNA polymerase B; Hedgehog/intein hint domain protein; KEGG: hwa:HQ1705A family B DNA-directed DNA polymerase. (1353 aa) |
| | rad50 | SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex. Belongs to the SMC family. RAD50 subfamily. (890 aa) |
| | mre11 | Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. (469 aa) |
| | pan | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] (403 aa) |
| | Huta_0344 | KEGG: nph:NP1636A hypothetical protein; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region. (228 aa) |
| | Huta_0341 | TIGRFAM: RNA methylase, NOL1/NOP2/sun family; PFAM: Fmu (Sun) domain protein; KEGG: hma:rrnAC0628 tRNA and rRNA cytosine-C5- methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (302 aa) |
| | Huta_0339 | PFAM: protein of unknown function DUF790; KEGG: nph:NP4066A hypothetical protein. (503 aa) |
| | Huta_0333 | PFAM: ABC transporter related; 4Fe-4S ferredoxin iron-sulfur binding domain protein; metal-binding domain in RNase L inhibitor, RLI; SMART: AAA ATPase; KEGG: hma:rrnAC2103 putative ATPase RIL. (610 aa) |
| | Huta_2796 | PFAM: metallophosphoesterase; KEGG: hma:rrnAC3502 hypothetical protein. (228 aa) |
| | Huta_0328 | TIGRFAM: HAD superfamily (subfamily IA) hydrolase, TIGR01548; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hma:rrnAC2106 hypothetical protein. (299 aa) |
| | Huta_0314 | KEGG: hma:rrnAC2116 excinuclease ABC subunit A; TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (988 aa) |
| | Huta_0291 | PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: nph:NP4170A DNA N-glycosylase / DNA lyase. (190 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (387 aa) |
| | Huta_0284 | Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (182 aa) |
| | Huta_0265 | PFAM: deoxyribodipyrimidine photolyase-related protein; DNA photolyase FAD-binding; KEGG: hma:rrnAC0506 cryptochrome/photolyase. (510 aa) |
| | rpl12 | Ribosomal protein 60S; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa) |
| | rpl10 | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (350 aa) |
| | rpl1 | Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (212 aa) |
| | rpl11 | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (162 aa) |
| | Huta_0250 | TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; TGS domain protein; KEGG: hma:rrnAC1411 GTP-binding protein Drg. (370 aa) |
| | Huta_0242 | Methyltransferase; PFAM: protein of unknown function Met10; KEGG: hma:rrnAC1405 methyltransferase. (326 aa) |
| | Huta_0231 | PFAM: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; SMART: Transcription factor TFIIS; DNA-directed RNA polymerase, M/15 kDa subunit; KEGG: hma:rrnAC0218 DNA-directed RNA-polymerase subunit M; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (106 aa) |
| | Huta_0228 | PFAM: tRNA methyltransferase complex GCD14 subunit; O-methyltransferase family 3; KEGG: nph:NP0356A methyltransferase. (243 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (905 aa) |
| | dnaG | TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (537 aa) |
| | Huta_0190 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: hsl:OE3121R putative phosphoglycolate phosphatase. (178 aa) |
| | Huta_0183 | PFAM: Uracil-DNA glycosylase superfamily; KEGG: hma:rrnAC0123 uracil DNA glycosylase superfamily protein. (210 aa) |
| | nucS | Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (255 aa) |
| | Huta_0154 | PFAM: integrase domain protein SAM domain protein; integrase family protein; KEGG: hma:rrnAC0375 integrase/recombinase. (353 aa) |
| | Huta_0141 | PFAM: PUA domain containing protein; SMART: PUA domain containing protein; KEGG: hma:rrnAC2087 PUA domain-containing protein. (167 aa) |
| | Huta_0136 | TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS605 OrfB; KEGG: nph:NP0974A IS1341-type transposase. (415 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (823 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (637 aa) |
| | top6B | DNA topoisomerase VI, B subunit; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (807 aa) |
| | top6A | DNA topoisomerase (ATP-hydrolyzing); Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (370 aa) |
| | Huta_0110 | PFAM: integrase family protein; KEGG: hsl:OE2438R integrase-like protein. (338 aa) |
| | Huta_0103 | PFAM: N-6 DNA methylase; putative RNA methylase; KEGG: hal:VNG0106G RmeM. (493 aa) |
| | Huta_0102 | PFAM: restriction modification system DNA specificity domain; KEGG: pmy:Pmen_0564 restriction modification system DNA specificity subunit. (442 aa) |
| | Huta_0101 | KEGG: hsl:OE1178F type I site-specific deoxyribonuclease subunit RmeR; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicases. (986 aa) |
| | Huta_0097 | KEGG: sus:Acid_6033 hypothetical protein. (91 aa) |
| | Huta_0088 | PFAM: glycosyl transferase group 1; KEGG: hma:rrnAC1352 glycosyltransferase. (369 aa) |
| | gatA | glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (434 aa) |
| | gatC | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (92 aa) |
| | Huta_0072 | Transposase; PFAM: Protein of unknown function DUF1225; transposase IS605 OrfB; KEGG: hma:pNG3034 transposase and inactivated derivatives. (446 aa) |
| | cysS | KEGG: hma:rrnAC1292 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M). (496 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (709 aa) |
| | rfcL | AAA ATPase central domain protein; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (507 aa) |
| | Huta_3008 | KEGG: hma:rrnAC3452 hypothetical protein. (296 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase, subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (413 aa) |
| | Huta_2974 | KEGG: hsl:OE2052F hypothetical protein. (217 aa) |
| | Huta_2966 | KEGG: hma:pNG7150 copper-binding protein. (633 aa) |
| | Huta_2945 | TIGRFAM: transposase, IS605 OrfB family; PFAM: Protein of unknown function DUF1225; transposase IS605 OrfB; KEGG: hsl:OE6034F IS1341-type transposase (TCE32). (450 aa) |
| | Huta_2939 | PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; KEGG: hma:rrnAC0987 A/G-specific adenine glycosylase. (306 aa) |
| | Huta_2931 | PFAM: nucleic acid binding OB-fold tRNA/helicase- type; RNA binding S1 domain protein; SMART: RNA binding S1 domain protein; KEGG: hma:rrnAC0979 putative nuclease. (730 aa) |
| | Huta_2928 | PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: hma:rrnAC0969 hypothetical protein. (707 aa) |
| | pelA | Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (356 aa) |
| | Huta_2920 | TIGRFAM: leucyl-tRNA synthetase; KEGG: hma:rrnAC2650 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (898 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (697 aa) |
| | Huta_2908 | PFAM: deoxyribonuclease/rho motif-related TRAM; KEGG: hma:rrnAC1808 hypothetical protein. (132 aa) |
| | Huta_2893 | KEGG: nph:NP0918A methylated-DNA--protein-cysteine methyltransferase. (168 aa) |
| | Huta_2879 | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: hma:rrnAC0832 deoxyribodipyrimidine photolyase. (470 aa) |
| | fusA | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] (729 aa) |
| | Huta_2819 | PFAM: DEAD/H associated domain protein; DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein; KEGG: hma:rrnAC0959 ATP-dependent helicase. (915 aa) |
| | Huta_2810 | PFAM: glycosyl transferase group 1; KEGG: hma:rrnAC1350 putative sugar transferase. (356 aa) |
| | Huta_2809 | PFAM: protein of unknown function DUF368; KEGG: nph:NP3722A hypothetical protein. (305 aa) |
| | Huta_2808 | PFAM: Oligosaccharyl transferase STT3 subunit; KEGG: hma:rrnAC0431 transmembrane oligosaccharyl transferase. (1045 aa) |
| | psmA-2 | Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (271 aa) |
