(74 nodes) Exocytic vesicle network (Atta colombica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ALC53_00804	Uncharacterized protein. (1736 aa)
	ALC53_01050	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (604 aa)
	ALC53_00805	Protein unc-13 like protein B. (1407 aa)
	ALC53_00803	Uncharacterized protein. (236 aa)
	ALC53_00876	Otoferlin. (2050 aa)
	ALC53_00903	Double C2-like domain-containing protein beta. (746 aa)
	ALC53_00648	Uncharacterized protein. (368 aa)
	ALC53_00698	Chloride channel protein. (830 aa)
	ALC53_00376	Extended synaptotagmin-2. (860 aa)
	ALC53_03423	Synaptobrevin. (308 aa)
	ALC53_03033	Synaptotagmin-7. (405 aa)
	ALC53_02713	Calcineurin subunit B type 2. (183 aa)
	ALC53_02499	Membrane-associated transporter protein. (639 aa)
	ALC53_02922	Uncharacterized protein. (329 aa)
	ALC53_02570	Protein unc-13 like protein D. (1234 aa)
	ALC53_01515	ATP-binding cassette sub-family G member 1. (931 aa)
	ALC53_00802	Phorbol ester/diacylglycerol-binding protein unc-13. (1279 aa)
	ALC53_12674	Loss of heterozygosity 12 chromosomal region 1 protein like protein. (535 aa)
	ALC53_11429	Vesicular glutamate transporter 2. (640 aa)
	ALC53_11431	Synaptotagmin 1. (436 aa)
	ALC53_10217	Vesicle transport through interaction with t-SNAREs like protein 1B. (114 aa)
	ALC53_08690	Synaptic vesicular amine transporter. (505 aa)
	ALC53_08611	Secretory carrier-associated membrane protein. (352 aa)
	ALC53_08598	Phosphatidylinositol-binding clathrin assembly protein LAP. (851 aa)
	ALC53_09164	Cysteine string protein. (207 aa)
	ALC53_08538	Protein stoned-A. (861 aa)
	ALC53_08537	Protein stoned-B; Belongs to the Stoned B family. (1198 aa)
	ALC53_08237	Vesicular inhibitory amino acid transporter. (563 aa)
	ALC53_07347	Uncharacterized protein. (192 aa)
	ALC53_07886	Rab3 GTPase-activating protein non-catalytic subunit. (1424 aa)
	ALC53_05040	SNARE-associated protein Snapin. (154 aa)
	ALC53_04259	Ras-related protein Rab-40C. (365 aa)
	ALC53_05037	Uncharacterized protein. (114 aa)
	ALC53_04367	Syntaxin-6. (312 aa)
	ALC53_03174	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (442 aa)
	ALC53_00759	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily. (705 aa)
	ALC53_14084	Calcium-dependent secretion activator. (1408 aa)
	ALC53_14030	Synapsin. (596 aa)
	ALC53_13819	Syntaxin-12; Belongs to the syntaxin family. (275 aa)
	ALC53_13840	UPF0764 protein C16orf89 like protein. (311 aa)
	ALC53_13216	Ras-related protein Rab-35. (201 aa)
	ALC53_12068	Uncharacterized protein. (1834 aa)
	ALC53_12123	Synaptotagmin-like protein 5. (3355 aa)
	ALC53_11849	Septin-4; Belongs to the FBPase class 1 family. (697 aa)
	ALC53_10570	Ras-related protein Rab-10. (200 aa)
	ALC53_10864	BAI1-associated protein 3. (1318 aa)
	ALC53_10793	Multiple C2 and transmembrane domain-containing protein 2. (1319 aa)
	ALC53_09549	Uncharacterized protein. (814 aa)
	ALC53_09548	Ras-related protein Rab-8A. (209 aa)
	ALC53_09023	Synaptotagmin-3. (407 aa)
	ALC53_09021	PRKCA-binding protein. (425 aa)
	ALC53_09065	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (219 aa)
	ALC53_08489	Uncharacterized protein. (422 aa)
	ALC53_08151	Uncharacterized protein. (283 aa)
	ALC53_08488	Synaptotagmin-C. (625 aa)
	ALC53_07919	Synaptotagmin-11. (444 aa)
	ALC53_07988	Dopamine receptor 2; Belongs to the G-protein coupled receptor 1 family. (534 aa)
	ALC53_06797	MAP kinase-activating death domain protein. (1901 aa)
	ALC53_06803	Ras-related protein Rab-27A. (208 aa)
	ALC53_07177	Ras-related protein Rab-9A. (232 aa)
	ALC53_06581	Septin-1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (360 aa)
	ALC53_06577	Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (562 aa)
	ALC53_06671	Ras-related protein Rab-8A. (208 aa)
	ALC53_06277	Protein wntless. (501 aa)
	ALC53_06345	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (591 aa)
	ALC53_05697	Synaptotagmin-9. (492 aa)
	ALC53_04980	Guanine nucleotide exchange factor for Rab-3A. (582 aa)
	ALC53_04549	Neurocalcin like protein. (192 aa)
	ALC53_04547	Neuronal calcium sensor 2. (267 aa)
	ALC53_04964	Zinc transporter SLC39A7. (403 aa)
	ALC53_04458	Otoferlin. (2133 aa)
	ALC53_03540	Synaptic vesicular amine transporter. (432 aa)
	ALC53_03422	Synaptobrevin. (147 aa)
	ALC53_03346	Calcium channel flower. (230 aa)

Your Current Organism:

Atta colombica

NCBI taxonomy Id: 520822
Other names: A. colombica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALC53_00376	ALC53_03422	A0A195BY19	A0A195BNB1	Extended synaptotagmin-2.	Synaptobrevin.	0.635
ALC53_00376	ALC53_03423	A0A195BY19	A0A195BPV3	Extended synaptotagmin-2.	Synaptobrevin.	0.635
ALC53_00376	ALC53_08537	A0A195BY19	A0A151I2J0	Extended synaptotagmin-2.	Protein stoned-B; Belongs to the Stoned B family.	0.574
ALC53_00376	ALC53_08598	A0A195BY19	A0A151I240	Extended synaptotagmin-2.	Phosphatidylinositol-binding clathrin assembly protein LAP.	0.640
ALC53_00376	ALC53_09065	A0A195BY19	A0A195B8E6	Extended synaptotagmin-2.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.677
ALC53_00376	ALC53_10793	A0A195BY19	A0A195B3G7	Extended synaptotagmin-2.	Multiple C2 and transmembrane domain-containing protein 2.	0.535
ALC53_00759	ALC53_03174	A0A151I5Z7	A0A151I5D8	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.567
ALC53_00759	ALC53_03422	A0A151I5Z7	A0A195BNB1	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Synaptobrevin.	0.708
ALC53_00759	ALC53_03423	A0A151I5Z7	A0A195BPV3	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Synaptobrevin.	0.708
ALC53_00759	ALC53_04367	A0A151I5Z7	A0A151I4Y1	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Syntaxin-6.	0.740
ALC53_00759	ALC53_07177	A0A151I5Z7	A0A195BDU7	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Ras-related protein Rab-9A.	0.594
ALC53_00759	ALC53_09021	A0A151I5Z7	A0A195B7I0	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	PRKCA-binding protein.	0.529
ALC53_00759	ALC53_10217	A0A151I5Z7	A0A151I0G4	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Vesicle transport through interaction with t-SNAREs like protein 1B.	0.683
ALC53_00759	ALC53_13819	A0A151I5Z7	A0A195AUA2	Spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation; Belongs to the AAA ATPase family. Spastin subfamily.	Syntaxin-12; Belongs to the syntaxin family.	0.706
ALC53_00802	ALC53_00903	A0A195BUT8	A0A195BWV1	Phorbol ester/diacylglycerol-binding protein unc-13.	Double C2-like domain-containing protein beta.	0.430
ALC53_00802	ALC53_03033	A0A195BUT8	A0A195BPW5	Phorbol ester/diacylglycerol-binding protein unc-13.	Synaptotagmin-7.	0.576
ALC53_00802	ALC53_03422	A0A195BUT8	A0A195BNB1	Phorbol ester/diacylglycerol-binding protein unc-13.	Synaptobrevin.	0.722
ALC53_00802	ALC53_03423	A0A195BUT8	A0A195BPV3	Phorbol ester/diacylglycerol-binding protein unc-13.	Synaptobrevin.	0.722
ALC53_00802	ALC53_03540	A0A195BUT8	A0A195BMY8	Phorbol ester/diacylglycerol-binding protein unc-13.	Synaptic vesicular amine transporter.	0.621
ALC53_00802	ALC53_05697	A0A195BUT8	A0A195BI03	Phorbol ester/diacylglycerol-binding protein unc-13.	Synaptotagmin-9.	0.537