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Athe_0168 Athe_0168 birA birA Athe_0473 Athe_0473 ribH ribH Athe_0562 Athe_0562 Athe_0563 Athe_0563 Athe_0564 Athe_0564 Athe_0861 Athe_0861 nrdR nrdR Athe_1568 Athe_1568 Athe_2207 Athe_2207 Athe_2395 Athe_2395 bioB bioB bioA bioA bioD bioD Athe_2647 Athe_2647
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
Athe_0168KEGG: csc:Csac_2425 CopG family transcriptional regulator. (81 aa)
birAbiotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (314 aa)
Athe_0473TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Miro domain protein; KEGG: csc:Csac_1123 small GTP-binding protein. (403 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (155 aa)
Athe_0562KEGG: csc:Csac_0792 GTP cyclohydrolase II; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: GTP cyclohydrolase II; 34-dihydroxy-2-butanone 4-phosphate synthase; In the N-terminal section; belongs to the DHBP synthase family. (402 aa)
Athe_0563TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: csc:Csac_0793 riboflavin synthase subunit alpha. (192 aa)
Athe_0564Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (371 aa)
Athe_0861KEGG: csc:Csac_2681 nicotinate phosphoribosyltransferase. (39 aa)
nrdRATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (153 aa)
Athe_1568PFAM: nitroreductase; KEGG: csc:Csac_0665 nitroreductase. (191 aa)
Athe_2207PFAM: aminotransferase class I and II; glycine hydroxymethyltransferase; aminotransferase class-III; Orn/Lys/Arg decarboxylase major region; aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: csc:Csac_1225 glycine C-acetyltransferase. (416 aa)
Athe_2395PFAM: CMP/dCMP deaminase zinc-binding; KEGG: csc:Csac_0345 CMP/dCMP deaminase, zinc-binding. (143 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (337 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (449 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (243 aa)
Athe_2647PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tte:TTE1073 biotin synthase. (351 aa)
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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