STRINGSTRING
Athe_0173 Athe_0173 Athe_0217 Athe_0217 Athe_0218 Athe_0218 Athe_0432 Athe_0432 Athe_0628 Athe_0628 Athe_0646 Athe_0646 Athe_0736 Athe_0736 Athe_0784 Athe_0784 Athe_0787 Athe_0787 Athe_0788 Athe_0788 Athe_0978 Athe_0978 Athe_0979 Athe_0979 Athe_0989 Athe_0989 Athe_0990 Athe_0990 Athe_0991 Athe_0991 Athe_0992 Athe_0992 Athe_0993 Athe_0993 Athe_0994 Athe_0994 Athe_0995 Athe_0995 Athe_0996 Athe_0996 Athe_0997 Athe_0997 Athe_0998 Athe_0998 Athe_0999 Athe_0999 Athe_1000 Athe_1000 nusB nusB xseA xseA xseB xseB Athe_1004 Athe_1004 Athe_1006 Athe_1006 Athe_1225 Athe_1225 Athe_1229 Athe_1229 Athe_1270 Athe_1270 Athe_1271 Athe_1271 Athe_1336 Athe_1336 Athe_1337 Athe_1337 Athe_1680 Athe_1680 spoIIAB spoIIAB Athe_1682 Athe_1682 Athe_1789 Athe_1789 gpr gpr Athe_1791 Athe_1791 Athe_1792 Athe_1792 Athe_1793 Athe_1793 Athe_1953 Athe_1953 Athe_1954 Athe_1954 Athe_1955 Athe_1955 Athe_1956 Athe_1956 Athe_1957 Athe_1957 Athe_2287 Athe_2287 Athe_2583 Athe_2583 Athe_2584 Athe_2584 Athe_2601 Athe_2601 Athe_2731 Athe_2731 Athe_2732 Athe_2732 Athe_2733 Athe_2733 Athe_2765 Athe_2765 Athe_2766 Athe_2766 Athe_2767 Athe_2767
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Athe_0173TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: csc:Csac_2420 AbrB family transcriptional regulator. (80 aa)
Athe_0217KEGG: csc:Csac_0117 phosphoprotein phosphatase; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (764 aa)
Athe_0218TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; KEGG: csc:Csac_0118 SpoIID/LytB domain-containing protein. (358 aa)
Athe_0432Protein of unknown function DUF204; Probably functions as a manganese efflux pump. (208 aa)
Athe_0628TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein; KEGG: csc:Csac_1196 PRC-barrel domain-containing protein. (76 aa)
Athe_0646KEGG: csc:Csac_1212 hypothetical protein. (94 aa)
Athe_0736RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (219 aa)
Athe_0784Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (277 aa)
Athe_0787RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (244 aa)
Athe_0788RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (255 aa)
Athe_0978KEGG: csc:Csac_2146 dipicolinate synthase subunit A. (292 aa)
Athe_0979TIGRFAM: dipicolinic acid synthetase, B subunit; PFAM: flavoprotein; KEGG: csc:Csac_2145 dipicolinate synthase subunit B. (198 aa)
Athe_0989PFAM: metallophosphoesterase; KEGG: csc:Csac_2135 metallophosphoesterase. (259 aa)
Athe_0990SMART: AAA ATPase; KEGG: csc:Csac_2134 AAA ATPase. (313 aa)
Athe_0991KEGG: csc:Csac_2133 hypothetical protein. (160 aa)
Athe_0992TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation AC family protein; KEGG: csc:Csac_2132 stage III sporulation AC family protein. (66 aa)
Athe_0993KEGG: csc:Csac_2131 hypothetical protein. (128 aa)
Athe_0994KEGG: csc:Csac_2130 hypothetical protein. (370 aa)
Athe_0995KEGG: csc:Csac_2129 hypothetical protein. (164 aa)
Athe_0996KEGG: csc:Csac_2128 hypothetical protein. (184 aa)
Athe_0997KEGG: csc:Csac_2127 hypothetical protein. (178 aa)
Athe_0998PFAM: protein of unknown function DUF322; KEGG: csc:Csac_2126 hypothetical protein. (128 aa)
Athe_0999KEGG: csc:Csac_2125 hypothetical protein. (179 aa)
Athe_1000KEGG: csc:Csac_2124 hypothetical protein. (69 aa)
nusBNusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (134 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (454 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (86 aa)
Athe_1004PFAM: Polyprenyl synthetase; KEGG: csc:Csac_2120 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (299 aa)
Athe_1006TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: csc:Csac_2118 AbrB family transcriptional regulator. (183 aa)
Athe_1225PFAM: small acid-soluble spore protein alpha/beta type; KEGG: csc:Csac_1790 small acid-soluble spore protein, alpha/beta type. (65 aa)
Athe_1229PFAM: nucleoside recognition domain protein; KEGG: csc:Csac_1794 hypothetical protein. (325 aa)
Athe_1270TIGRFAM: sporulation protein YqfC; PFAM: protein of unknown function DUF1429; KEGG: csc:Csac_1835 hypothetical protein. (100 aa)
Athe_1271KEGG: csc:Csac_1836 hypothetical protein. (381 aa)
Athe_1336TIGRFAM: stage IV sporulation protein B; PFAM: peptidase S55 SpoIVB; KEGG: csc:Csac_1899 peptidase S55, SpoIVB. (413 aa)
Athe_1337Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (267 aa)
Athe_1680RNA polymerase, sigma 28 subunit, Sig B/F/G subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (232 aa)
spoIIABAnti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (154 aa)
Athe_1682Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: csc:Csac_1657 anti-sigma-factor antagonist. (109 aa)
Athe_1789TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: csc:Csac_2332 stage II sporulation P family protein. (377 aa)
gprSpore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. (327 aa)
Athe_1791KEGG: csc:Csac_2334 hypothetical protein. (57 aa)
Athe_1792TIGRFAM: germination protein YpeB; PFAM: Propeptide PepSY amd peptidase M4; KEGG: csc:Csac_2335 hypothetical protein. (466 aa)
Athe_1793PFAM: cell wall hydrolase SleB; KEGG: csc:Csac_2336 cell wall hydrolase, SleB. (185 aa)
Athe_1953KEGG: csc:Csac_0999 hypothetical protein. (230 aa)
Athe_1954TIGRFAM: germination protein, Ger(x)C family; PFAM: spore germination B3 GerAC family protein; KEGG: csc:Csac_0998 spore germination B3 GerAC family protein. (431 aa)
Athe_1955TIGRFAM: spore germination protein; PFAM: Spore germination protein; KEGG: csc:Csac_0997 spore germination protein. (368 aa)
Athe_1956PFAM: GerA spore germination protein; KEGG: csc:Csac_0996 GerA spore germination protein. (531 aa)
Athe_1957KEGG: amt:Amet_4601 hypothetical protein. (64 aa)
Athe_2287PFAM: CBS domain containing protein; SMART: CBS domain containing protein; KEGG: csc:Csac_0245 signal-transduction protein. (123 aa)
Athe_2583PFAM: nucleoside recognition domain protein; KEGG: csc:Csac_0422 nucleoside recognition domain-containing protein. (172 aa)
Athe_2584PFAM: nucleoside recognition domain protein; KEGG: csc:Csac_0421 nucleoside recognition domain-containing protein. (189 aa)
Athe_2601Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (491 aa)
Athe_2731TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: csc:Csac_0092 SpoVA protein. (152 aa)
Athe_2732TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: csc:Csac_0091 stage V sporulation protein AD. (336 aa)
Athe_2733TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: csc:Csac_0090 SpoVA protein. (117 aa)
Athe_2765PFAM: GerA spore germination protein; KEGG: csc:Csac_2777 GerA spore germination protein. (490 aa)
Athe_2766TIGRFAM: spore germination protein; PFAM: Spore germination protein; KEGG: csc:Csac_2778 spore germination protein. (368 aa)
Athe_2767TIGRFAM: germination protein, Ger(x)C family; PFAM: spore germination B3 GerAC family protein; KEGG: csc:Csac_2779 spore germination B3 GerAC family protein. (374 aa)
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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