STRINGSTRING
Athe_1271 Athe_1271 Athe_0049 Athe_0049 Athe_0173 Athe_0173 Athe_0217 Athe_0217 Athe_0218 Athe_0218 Athe_0244 Athe_0244 Athe_0396 Athe_0396 Athe_0432 Athe_0432 Athe_0516 Athe_0516 Athe_0541 Athe_0541 Athe_0542 Athe_0542 Athe_0543 Athe_0543 Athe_0628 Athe_0628 Athe_0650 Athe_0650 Athe_0692 Athe_0692 Athe_0736 Athe_0736 Athe_0781 Athe_0781 Athe_0784 Athe_0784 Athe_0787 Athe_0787 Athe_0796 Athe_0796 Athe_0817 Athe_0817 Athe_0880 Athe_0880 Athe_0978 Athe_0978 Athe_0979 Athe_0979 Athe_0990 Athe_0990 Athe_0992 Athe_0992 Athe_0993 Athe_0993 Athe_0994 Athe_0994 Athe_0995 Athe_0995 Athe_0996 Athe_0996 Athe_0997 Athe_0997 Athe_1006 Athe_1006 Athe_1164 Athe_1164 Athe_1229 Athe_1229 Athe_1337 Athe_1337 Athe_1509 Athe_1509 Athe_1560 Athe_1560 spoIIAB spoIIAB Athe_1789 Athe_1789 Athe_1793 Athe_1793 Athe_1953 Athe_1953 Athe_1976 Athe_1976 Athe_2021 Athe_2021 spoVG spoVG Athe_2493 Athe_2493 Athe_2583 Athe_2583 Athe_2584 Athe_2584 Athe_2595 Athe_2595 Athe_2601 Athe_2601 Athe_2615 Athe_2615 Athe_2651 Athe_2651 Athe_2731 Athe_2731 Athe_2732 Athe_2732 Athe_2733 Athe_2733 Athe_2738 Athe_2738 Athe_2752 Athe_2752
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Athe_1271KEGG: csc:Csac_1836 hypothetical protein. (381 aa)
Athe_0049PFAM: protein of unknown function DUF95 transmembrane; KEGG: csc:Csac_2575 hypothetical protein. (191 aa)
Athe_0173TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: csc:Csac_2420 AbrB family transcriptional regulator. (80 aa)
Athe_0217KEGG: csc:Csac_0117 phosphoprotein phosphatase; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein. (764 aa)
Athe_0218TIGRFAM: stage II sporulation protein D; SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; KEGG: csc:Csac_0118 SpoIID/LytB domain-containing protein. (358 aa)
Athe_0244TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; KEGG: csc:Csac_0152 SpoIID/LytB domain-containing protein. (584 aa)
Athe_0396KEGG: csc:Csac_0277 hypothetical protein. (192 aa)
Athe_0432Protein of unknown function DUF204; Probably functions as a manganese efflux pump. (208 aa)
Athe_0516PFAM: PSP1 domain protein; KEGG: csc:Csac_0744 PSP1 domain-containing protein. (295 aa)
Athe_0541TIGRFAM: spore coat protein, CotS family; PFAM: aminoglycoside phosphotransferase; KEGG: csc:Csac_0767 hypothetical protein. (337 aa)
Athe_0542KEGG: csc:Csac_0768 hypothetical protein. (322 aa)
Athe_0543TIGRFAM: spore coat protein, CotS family; KEGG: csc:Csac_0769 hypothetical protein. (330 aa)
Athe_0628TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein; KEGG: csc:Csac_1196 PRC-barrel domain-containing protein. (76 aa)
Athe_0650PFAM: YabP family protein; KEGG: csc:Csac_1216 YabP family protein. (91 aa)
Athe_0692PFAM: protein of unknown function DUF964; KEGG: csc:Csac_0863 hypothetical protein; Belongs to the UPF0342 family. (119 aa)
Athe_0736RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (219 aa)
Athe_0781PFAM: protein of unknown function DUF881; KEGG: csc:Csac_0928 hypothetical protein. (247 aa)
Athe_0784Peptidase U4 sporulation factor SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (277 aa)
Athe_0787RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (244 aa)
Athe_0796TIGRFAM: sporulation protein YtfJ; KEGG: csc:Csac_0941 tubulin. (127 aa)
Athe_0817KEGG: csc:Csac_0965 hypothetical protein. (190 aa)
Athe_0880Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (667 aa)
Athe_0978KEGG: csc:Csac_2146 dipicolinate synthase subunit A. (292 aa)
Athe_0979TIGRFAM: dipicolinic acid synthetase, B subunit; PFAM: flavoprotein; KEGG: csc:Csac_2145 dipicolinate synthase subunit B. (198 aa)
Athe_0990SMART: AAA ATPase; KEGG: csc:Csac_2134 AAA ATPase. (313 aa)
Athe_0992TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation AC family protein; KEGG: csc:Csac_2132 stage III sporulation AC family protein. (66 aa)
Athe_0993KEGG: csc:Csac_2131 hypothetical protein. (128 aa)
Athe_0994KEGG: csc:Csac_2130 hypothetical protein. (370 aa)
Athe_0995KEGG: csc:Csac_2129 hypothetical protein. (164 aa)
Athe_0996KEGG: csc:Csac_2128 hypothetical protein. (184 aa)
Athe_0997KEGG: csc:Csac_2127 hypothetical protein. (178 aa)
Athe_1006TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: csc:Csac_2118 AbrB family transcriptional regulator. (183 aa)
Athe_1164PFAM: Stage V sporulation protein S; KEGG: csc:Csac_1613 stage V sporulation protein S. (86 aa)
Athe_1229PFAM: nucleoside recognition domain protein; KEGG: csc:Csac_1794 hypothetical protein. (325 aa)
Athe_1337Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (267 aa)
Athe_1509PFAM: heat shock protein Hsp20; KEGG: csc:Csac_2056 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (148 aa)
Athe_1560TIGRFAM: spore cortex-lytic enzyme; PFAM: cell wall hydrolase SleB; Peptidoglycan-binding domain 1 protein; KEGG: csc:Csac_1743 cell wall hydrolase, SleB. (225 aa)
spoIIABAnti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (154 aa)
Athe_1789TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: csc:Csac_2332 stage II sporulation P family protein. (377 aa)
Athe_1793PFAM: cell wall hydrolase SleB; KEGG: csc:Csac_2336 cell wall hydrolase, SleB. (185 aa)
Athe_1953KEGG: csc:Csac_0999 hypothetical protein. (230 aa)
Athe_1976PFAM: Coat F domain protein; KEGG: csc:Csac_2706 coat F domain-containing protein. (93 aa)
Athe_2021KEGG: csc:Csac_1444 radical SAM domain-containing protein. (109 aa)
spoVGSpoVG family protein; Could be involved in septation. (88 aa)
Athe_2493PFAM: Radical SAM domain protein; KEGG: csc:Csac_2613 radical SAM domain-containing protein. (253 aa)
Athe_2583PFAM: nucleoside recognition domain protein; KEGG: csc:Csac_0422 nucleoside recognition domain-containing protein. (172 aa)
Athe_2584PFAM: nucleoside recognition domain protein; KEGG: csc:Csac_0421 nucleoside recognition domain-containing protein. (189 aa)
Athe_2595KEGG: csc:Csac_0382 DNA repair photolyase-like protein. (336 aa)
Athe_2601Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (491 aa)
Athe_2615PFAM: protein of unknown function DUF95 transmembrane; KEGG: csc:Csac_0525 hypothetical protein. (182 aa)
Athe_2651PFAM: Domain of unknown function DUF1848; KEGG: csc:Csac_0047 hypothetical protein. (360 aa)
Athe_2731TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: csc:Csac_0092 SpoVA protein. (152 aa)
Athe_2732TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: csc:Csac_0091 stage V sporulation protein AD. (336 aa)
Athe_2733TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: csc:Csac_0090 SpoVA protein. (117 aa)
Athe_2738PFAM: Stage V sporulation protein S; KEGG: csc:Csac_0022 stage V sporulation protein S. (86 aa)
Athe_2752PFAM: Cobyrinic acid ac-diamide synthase; KEGG: csc:Csac_2765 cobyrinic acid a,c-diamide synthase. (262 aa)
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.