STRINGSTRING
Athe_0038 Athe_0038 Athe_0042 Athe_0042 Athe_0050 Athe_0050 Athe_0192 Athe_0192 Athe_0212 Athe_0212 Athe_0440 Athe_0440 Athe_0457 Athe_0457 leuA leuA Athe_0507 Athe_0507 Athe_0518 Athe_0518 Athe_0589 Athe_0589 Athe_0604 Athe_0604 Athe_0631 Athe_0631 Athe_0656 Athe_0656 Athe_0680 Athe_0680 Athe_0704 Athe_0704 Athe_0819 Athe_0819 Athe_0832 Athe_0832 pheA pheA Athe_0973 Athe_0973 Athe_1004 Athe_1004 Athe_1032 Athe_1032 Athe_1055 Athe_1055 Athe_1061 Athe_1061 Athe_1065 Athe_1065 argB argB argC argC Athe_1105 Athe_1105 Athe_1113 Athe_1113 Athe_1124 Athe_1124 Athe_1126 Athe_1126 sbcD sbcD Athe_1158 Athe_1158 Athe_1190 Athe_1190 hemA hemA rplT rplT Athe_1211 Athe_1211 Athe_1214 Athe_1214 Athe_1230 Athe_1230 Athe_1232 Athe_1232 Athe_1234 Athe_1234 nadD nadD ybeY ybeY Athe_1277 Athe_1277 Athe_1315 Athe_1315 purD purD purF purF Athe_1464 Athe_1464 Athe_1468 Athe_1468 Athe_1517 Athe_1517 Athe_1524 Athe_1524 ispE ispE Athe_1547 Athe_1547 Athe_1599 Athe_1599 Athe_1617 Athe_1617 Athe_1625 Athe_1625 ychF ychF truA truA Athe_1699 Athe_1699 iscS iscS Athe_1723 Athe_1723 adk adk rplP rplP rplV rplV Athe_1785 Athe_1785 mcsB mcsB Athe_1841 Athe_1841 Athe_1864 Athe_1864 Athe_1899 Athe_1899 pdxS pdxS Athe_1911 Athe_1911 Athe_1938 Athe_1938 Athe_2034 Athe_2034 mrnC mrnC Athe_2060 Athe_2060 Athe_2072 Athe_2072 Athe_2086 Athe_2086 Athe_2118 Athe_2118 Athe_2126 Athe_2126 fhs fhs Athe_2226 Athe_2226 Athe_2262 Athe_2262 Athe_2319 Athe_2319 Athe_2360 Athe_2360 Athe_2362 Athe_2362 Athe_2363 Athe_2363 Athe_2385 Athe_2385 Athe_2395 Athe_2395 Athe_2396 Athe_2396 Athe_2538 Athe_2538 bioB bioB Athe_2560 Athe_2560 Athe_2608 Athe_2608 Athe_2609 Athe_2609 Athe_2611 Athe_2611 Athe_2641 Athe_2641 Athe_2647 Athe_2647 Athe_2687 Athe_2687 Athe_2713 Athe_2713 Athe_2754 Athe_2754
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Athe_0038KEGG: csc:Csac_0698 hypothetical protein. (794 aa)
Athe_0042PFAM: ATPase associated with various cellular activities AAA_3; magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: csc:Csac_0702 ATPase. (325 aa)
Athe_0050KEGG: csc:Csac_2574 Zn-dependent hydrolase of the beta-lactamase fold-like protein. (210 aa)
Athe_0192TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: csc:Csac_0101 putative endoribonuclease L-PSP. (125 aa)
Athe_0212KEGG: csc:Csac_0112 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (157 aa)
Athe_0440PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: csc:Csac_0210 putative 6-pyruvoyl tetrahydropterin synthase. (120 aa)
Athe_0457methylated-DNA/protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (160 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (507 aa)
Athe_0507TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; KEGG: csc:Csac_1146 alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (526 aa)
Athe_0518PFAM: pyruvate carboxyltransferase; KEGG: csc:Csac_0746 pyruvate carboxyltransferase. (465 aa)
Athe_0589TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: csc:Csac_0826 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (285 aa)
Athe_0604KEGG: csc:Csac_0687 hypothetical protein. (235 aa)
Athe_0631PFAM: beta-lactamase domain protein; KEGG: csc:Csac_1199 beta-lactamase domain-containing protein. (265 aa)
Athe_0656PFAM: MgtE intracellular region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: csc:Csac_1222 MgtE intracellular region. (417 aa)
Athe_0680PFAM: protein of unknown function UPF0047; KEGG: csc:Csac_0854 hypothetical protein. (138 aa)
Athe_0704PFAM: Transketolase central region; dehydrogenase E1 component; Transketolase domain protein; KEGG: csc:Csac_0874 transketolase, central region. (823 aa)
Athe_0819PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: csc:Csac_0967 5-carboxymethyl-2-hydroxymuconate delta-isomerase. (249 aa)
Athe_0832PFAM: GCN5-related N-acetyltransferase; KEGG: csc:Csac_0980 GCN5-related N-acetyltransferase. (128 aa)
pheAPFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: csc:Csac_1462 prephenate dehydratase. (277 aa)
Athe_0973GTP-binding protein HSR1-related protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (282 aa)
Athe_1004PFAM: Polyprenyl synthetase; KEGG: csc:Csac_2120 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (299 aa)
Athe_1032PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; KEGG: csc:Csac_2089 hydantoinase/oxoprolinase. (546 aa)
Athe_1055TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase; FAD synthetase; cytidylyltransferase; KEGG: csc:Csac_2066 riboflavin biosynthesis protein RibF; Belongs to the ribF family. (305 aa)
Athe_1061PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: csc:Csac_2060 recombination factor protein RarA. (441 aa)
Athe_1065PFAM: 8-oxoguanine DNA glycosylase domain protein; HhH-GPD family protein; SMART: HhH-GPD family protein; KEGG: csc:Csac_1515 8-oxoguanine DNA glycosylase domain-containing protein. (284 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (293 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa)
Athe_1105PFAM: GCN5-related N-acetyltransferase; KEGG: csc:Csac_1563 GCN5-related N-acetyltransferase. (158 aa)
Athe_1113PFAM: GCN5-related N-acetyltransferase; KEGG: csc:Csac_1563 GCN5-related N-acetyltransferase. (160 aa)
Athe_1124KEGG: csc:Csac_1574 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. (425 aa)
Athe_1126PFAM: beta-lactamase domain protein; KEGG: csc:Csac_1576 beta-lactamase domain-containing protein. (240 aa)
sbcDNuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (420 aa)
Athe_11583-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
Athe_1190O-acetylhomoserine aminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: csc:Csac_1639 O-acetylhomoserine aminocarboxypropyltransferase. (409 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (394 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
Athe_1211Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (138 aa)
Athe_1214KEGG: csc:Csac_1779 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family. (278 aa)
Athe_1230PFAM: Patatin; KEGG: csc:Csac_1795 patatin. (252 aa)
Athe_1232PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: csc:Csac_1797 acyl-CoA dehydrogenase domain-containing protein. (381 aa)
Athe_1234PFAM: Electron transfer flavoprotein alpha subunit; KEGG: csc:Csac_1799 electron transfer flavoprotein, alpha subunit. (334 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (196 aa)
ybeYProtein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (158 aa)
Athe_1277PFAM: RNA-metabolising metallo-beta-lactamase; beta-lactamase domain protein; KEGG: csc:Csac_1842 RNA-metabolising metallo-beta-lactamase. (540 aa)
Athe_1315TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: csc:Csac_1880 putative agmatinase; Belongs to the arginase family. (285 aa)
purDKEGG: csc:Csac_1991 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (420 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (474 aa)
Athe_1464PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: csc:Csac_2011 UBA/ThiF-type NAD/FAD binding protein. (242 aa)
Athe_1468KEGG: cth:Cthe_1283 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop. (178 aa)
Athe_1517PFAM: protein of unknown function UPF0047; KEGG: csc:Csac_2192 hypothetical protein. (130 aa)
Athe_1524TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: csc:Csac_2200 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (849 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (286 aa)
Athe_1547PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: csc:Csac_1756 aminotransferase, class V. (382 aa)
Athe_1599PFAM: helicase domain protein; SNF2-related protein; type III restriction protein res subunit; SMART: DEAD-like helicases; helicase domain protein; KEGG: cyb:CYB_1727 SNF2 family helicase. (889 aa)
Athe_1617PFAM: ABC-1 domain protein; KEGG: csc:Csac_1734 hypothetical protein. (547 aa)
Athe_1625TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: csc:Csac_1727 thioredoxin; Belongs to the thioredoxin family. (108 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (362 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (244 aa)
Athe_1699PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease family 2; KEGG: csc:Csac_2239 xylose isomerase domain-containing protein. (286 aa)
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (394 aa)
Athe_1723KEGG: csc:Csac_2265 hypothetical protein. (89 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (147 aa)
rplVRibosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (120 aa)
Athe_1785PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; KEGG: csc:Csac_2328 hypothetical protein. (446 aa)
mcsBATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins. (328 aa)
Athe_1841KEGG: csc:Csac_2383 beta-lactamase superfamily hydrolase. (241 aa)
Athe_1864PFAM: glycosyl transferase family 39; KEGG: csc:Csac_1081 glycosyl transferase family protein. (566 aa)
Athe_1899PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: csc:Csac_1045 cytochrome c biogenesis protein, transmembrane region. (215 aa)
pdxSPyridoxine biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (296 aa)
Athe_1911Amidohydrolase; KEGG: csc:Csac_1034 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein. (375 aa)
Athe_1938PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: csc:Csac_1014 beta-lactamase domain-containing protein. (821 aa)
Athe_2034PFAM: ferredoxin-dependent glutamate synthase; KEGG: csc:Csac_1377 ferredoxin-dependent glutamate synthase. (529 aa)
mrnCRibonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (145 aa)
Athe_2060PFAM: Transketolase domain protein; KEGG: csc:Csac_1351 transketolase domain-containing protein. (282 aa)
Athe_2072Alpha-L-fucosidase; PFAM: glycoside hydrolase family 29 (alpha-L-fucosidase); KEGG: csc:Csac_1340 alpha-L-fucosidase. (486 aa)
Athe_2086Beta-glucuronidase; PFAM: glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 sugar binding; KEGG: dth:DICTH_1429 beta-glucuronidase; Belongs to the glycosyl hydrolase 2 family. (512 aa)
Athe_2118PFAM: PfkB domain protein; KEGG: csc:Csac_1312 ribokinase-like domain-containing protein. (307 aa)
Athe_2126PFAM: aminotransferase class V; KEGG: csc:Csac_1303 aminotransferase, class V. (386 aa)
fhsPFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: csc:Csac_1224 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (552 aa)
Athe_2226PFAM: pyruvate carboxyltransferase; KEGG: csc:Csac_0724 pyruvate carboxyltransferase. (452 aa)
Athe_2262SMART: metal-dependent phosphohydrolase HD region; KEGG: pth:PTH_2562 phosphohydrolases. (427 aa)
Athe_2319Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: csc:Csac_0626 helix-turn-helix domain-containing protein. (124 aa)
Athe_2360PFAM: ferredoxin-dependent glutamate synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: csc:Csac_0578 glutamate synthase (NADPH); Belongs to the glutamate synthase family. (502 aa)
Athe_2362PFAM: Cupin 2 conserved barrel domain protein; KEGG: csc:Csac_0542 cupin 2 domain-containing protein. (107 aa)
Athe_2363TIGRFAM: calcium-translocating P-type ATPase, PMCA-type; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: csc:Csac_0369 calcium-translocating P-type ATPase, PMCA-type. (885 aa)
Athe_2385PFAM: PfkB domain protein; KEGG: csc:Csac_2720 ribokinase-like domain-containing protein. (342 aa)
Athe_2395PFAM: CMP/dCMP deaminase zinc-binding; KEGG: csc:Csac_0345 CMP/dCMP deaminase, zinc-binding. (143 aa)
Athe_2396KEGG: csc:Csac_0344 hypothetical protein. (442 aa)
Athe_2538Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: aau:AAur_3964 helix-turn-helix domain-containing protein. (145 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (337 aa)
Athe_2560PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: csc:Csac_0291 ATPase. (315 aa)
Athe_2608PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: csc:Csac_0531 ABC transporter related. (246 aa)
Athe_2609PFAM: SufBD protein; KEGG: csc:Csac_0530 SufBD protein. (416 aa)
Athe_2611TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein; KEGG: csc:Csac_0528 RND family efflux transporter MFP subunit. (549 aa)
Athe_2641TIGRFAM: redox-active disulfide protein 2; KEGG: csc:Csac_0498 redox-active disulfide protein 2. (81 aa)
Athe_2647PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tte:TTE1073 biotin synthase. (351 aa)
Athe_2687PFAM: beta-lactamase domain protein; KEGG: mja:MJ0162 putative mRNA 3'-end processing factor 3. (591 aa)
Athe_2713PFAM: Rhomboid family protein; KEGG: chy:CHY_0820 rhomboid family protein. (227 aa)
Athe_2754KEGG: csc:Csac_2767 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family. (547 aa)
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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