STRINGSTRING
Plim_1722 Plim_1722 serC serC Plim_1784 Plim_1784 kbl kbl glyA glyA dxs dxs Plim_2467 Plim_2467 Plim_2472 Plim_2472 Plim_2596 Plim_2596 Plim_2637 Plim_2637 hemL hemL argD argD Plim_2892 Plim_2892 Plim_2906 Plim_2906 Plim_2963 Plim_2963 Plim_3177 Plim_3177 Plim_3306 Plim_3306 hisC hisC Plim_3493 Plim_3493 Plim_3530 Plim_3530 Plim_3657 Plim_3657 Plim_3794 Plim_3794 Plim_3995 Plim_3995 Plim_4098 Plim_4098 Plim_1470 Plim_1470 Plim_1406 Plim_1406 Plim_1143 Plim_1143 Plim_0887 Plim_0887 Plim_0622 Plim_0622 Plim_0611 Plim_0611 Plim_0462 Plim_0462 Plim_0452 Plim_0452 Plim_0230 Plim_0230 Plim_0135 Plim_0135 Plim_1672 Plim_1672 Plim_1678 Plim_1678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Plim_1722PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: scl:sce3847 putative serine/threonine dehydratase. (320 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (360 aa)
Plim_1784PFAM: Ethanolamine ammonia-lyase light chain; KEGG: cvi:CV_1184 ethanolamine ammonia-lyase small subunit; Belongs to the EutC family. (279 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (394 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (630 aa)
Plim_2467Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1261 aa)
Plim_2472Hypothetical protein. (271 aa)
Plim_2596Glycine dehydrogenase (decarboxylating); KEGG: bmn:BMA10247_2126 hypothetical protein. (491 aa)
Plim_2637Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (499 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase. (452 aa)
argDAcetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (403 aa)
Plim_2892Aminotransferase class I and II; KEGG: bma:BMAA1451.2 hypothetical protein. (411 aa)
Plim_2906MOSC domain containing protein. (167 aa)
Plim_2963Threonine synthase. (483 aa)
Plim_3177Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1032 aa)
Plim_3306Cystathionine gamma-lyase. (391 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (358 aa)
Plim_3493Alpha-glucan phosphorylase. (713 aa)
Plim_3530Aminotransferase class I and II. (373 aa)
Plim_3657MOSC domain containing protein. (221 aa)
Plim_3794Cysteine desulfurase. (383 aa)
Plim_3995Aminotransferase class I and II; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily. (411 aa)
Plim_4098O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: proteophosphoglycan 5. (432 aa)
Plim_14708-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; Orn/Lys/Arg decarboxylase major region; KEGG: mxa:MXAN_1258 8-amino-7-oxononanoate synthase. (402 aa)
Plim_1406TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP- binding; KEGG: CSR1; CSR1 (CHLORSULFURON/IMIDAZOLINONE RESISTANT 1); K01652 acetolactate synthase I/II/III large subunit. (593 aa)
Plim_1143PFAM: aminotransferase class-III; KEGG: dvu:DVU2559 adenosylmethionine--8-amino-7- oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa)
Plim_0887PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; KEGG: pca:Pcar_2858 pyruvate decarboxylase. (557 aa)
Plim_0622TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; KEGG: scl:sce5670 alpha-ketoglutarate decarboxylase. (928 aa)
Plim_0611Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. (382 aa)
Plim_0462TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Beta-ketoacyl synthase; KR domain protein; Acyl transferase; short-chain dehydrogenase/reductase SDR; KEGG: gur:Gura_2012 erythronolide synthase. (2414 aa)
Plim_0452Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (258 aa)
Plim_0230TIGRFAM: folate-binding protein YgfZ; PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: afw:Anae109_2780 glycine cleavage T-protein barrel; Belongs to the GcvT family. (329 aa)
Plim_0135PFAM: aminotransferase class I and II; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: gur:Gura_2501 aminotransferase, class I and II. (407 aa)
Plim_16726-deoxyerythronolide-B synthase., (Acyl-carrier- protein) S-malonyltransferase; PFAM: Beta-ketoacyl synthase; peptidase C45 acyl- coenzyme A:6-aminopenicillanic acid acyl-transferase; Acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; KEGG: acp:A2cp1_4042 beta-ketoacyl synthase. (3527 aa)
Plim_1678PFAM: aminotransferase class I and II; KEGG: vha:VIBHAR_00447 valine--pyruvate transaminase. (426 aa)
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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