STRINGSTRING
accD accD panD panD Plim_3893 Plim_3893 Plim_3658 Plim_3658 lipA lipA Plim_3323 Plim_3323 Plim_3297 Plim_3297 Plim_3124 Plim_3124 Plim_3122 Plim_3122 Plim_3121 Plim_3121 Plim_3120 Plim_3120 Plim_2980 Plim_2980 plsX plsX Plim_2566 Plim_2566 acpP acpP Plim_2564 Plim_2564 Plim_2562 Plim_2562 panC panC fabH fabH accA accA kbl kbl bioB bioB Plim_1694 Plim_1694 Plim_1672 Plim_1672 panB panB Plim_1572 Plim_1572 Plim_1483 Plim_1483 Plim_1470 Plim_1470 Plim_1143 Plim_1143 Plim_0833 Plim_0833 Plim_0729 Plim_0729 Plim_0566 Plim_0566 bioD bioD Plim_0462 Plim_0462 Plim_0145 Plim_0145 Plim_0064 Plim_0064
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (285 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (120 aa)
Plim_3893Short-chain dehydrogenase/reductase SDR. (273 aa)
Plim_3658Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (439 aa)
lipALipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (288 aa)
Plim_33233-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III domain protein. (387 aa)
Plim_3297Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ. (175 aa)
Plim_3124Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ. (167 aa)
Plim_3122Phosphopantetheine-binding protein. (128 aa)
Plim_3121Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ. (162 aa)
Plim_31203-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (429 aa)
Plim_2980Ketopantoate reductase ApbA/PanE domain protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (323 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (340 aa)
Plim_2566Malonyl CoA-acyl carrier protein transacylase. (304 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
Plim_25643-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
Plim_2562Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (435 aa)
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (289 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (424 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (340 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (394 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (376 aa)
Plim_1694PFAM: Beta-ketoacyl synthase; KEGG: ade:Adeh_2746 3-oxoacyl-[acyl-carrier- protein] synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (430 aa)
Plim_16726-deoxyerythronolide-B synthase., (Acyl-carrier- protein) S-malonyltransferase; PFAM: Beta-ketoacyl synthase; peptidase C45 acyl- coenzyme A:6-aminopenicillanic acid acyl-transferase; Acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; KEGG: acp:A2cp1_4042 beta-ketoacyl synthase. (3527 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (281 aa)
Plim_1572TIGRFAM: holo-acyl-carrier-protein synthase; KEGG: aba:Acid345_4518 phosphopantethiene--protein transferase domain; Belongs to the P-Pant transferase superfamily. (131 aa)
Plim_1483Hypothetical protein. (202 aa)
Plim_14708-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; Orn/Lys/Arg decarboxylase major region; KEGG: mxa:MXAN_1258 8-amino-7-oxononanoate synthase. (402 aa)
Plim_1143PFAM: aminotransferase class-III; KEGG: dvu:DVU2559 adenosylmethionine--8-amino-7- oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa)
Plim_0833Hypothetical protein. (256 aa)
Plim_0729PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pmy:Pmen_3191 alcohol dehydrogenase. (344 aa)
Plim_0566PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mlo:mll3915 alcohol dehydrogenase (NADPH quinone oxidoreductase). (343 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (248 aa)
Plim_0462TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Beta-ketoacyl synthase; KR domain protein; Acyl transferase; short-chain dehydrogenase/reductase SDR; KEGG: gur:Gura_2012 erythronolide synthase. (2414 aa)
Plim_0145KEGG: rce:RC1_1209 hypothetical protein. (178 aa)
Plim_0064acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (167 aa)
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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