STRINGSTRING
lpxK lpxK Plim_0552 Plim_0552 hldE hldE Plim_0899 Plim_0899 Plim_0900 Plim_0900 Plim_0901 Plim_0901 Plim_0918 Plim_0918 Plim_0919 Plim_0919 Plim_0943 Plim_0943 Plim_1528 Plim_1528 kdsB kdsB Plim_1862 Plim_1862 lpxD lpxD Plim_2366 Plim_2366 Plim_3740 Plim_3740 Plim_4193 Plim_4193
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (375 aa)
Plim_0552PFAM: PfkB domain protein; KEGG: sus:Acid_3554 ribokinase-like domain- containing protein. (349 aa)
hldECytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (520 aa)
Plim_0899TIGRFAM: lipopolysaccharide heptosyltransferase II; PFAM: glycosyl transferase family 9; KEGG: glo:Glov_0772 lipopolysaccharide heptosyltransferase II. (354 aa)
Plim_0900PFAM: glycosyl transferase group 1; KEGG: cvi:CV_0817 glycosyltransferase. (381 aa)
Plim_0901PFAM: lipopolysaccharide kinase; KEGG: cja:CJA_0503 lipopolysaccharide core biosynthesis protein WaaP. (268 aa)
Plim_0918acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (282 aa)
Plim_0919UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. (311 aa)
Plim_0943lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (391 aa)
Plim_1528KEGG: sus:Acid_2237 sugar isomerase (SIS). (204 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
Plim_1862PFAM: lipid A biosynthesis acyltransferase; KEGG: sfu:Sfum_0376 lipid A biosynthesis acyltransferase. (312 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl) glucosamine N- acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (366 aa)
Plim_2366Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (465 aa)
Plim_3740KpsF/GutQ family protein. (391 aa)
Plim_41932-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (285 aa)
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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