STRINGSTRING
EHY70161.1 EHY70161.1 ppsA ppsA EHY70772.1 EHY70772.1 zwf zwf hycD hycD hycB hycB sdaB sdaB gapA gapA tdcG tdcG gpmA gpmA pgl pgl EHY69739.1 EHY69739.1 EHY69740.1 EHY69740.1 pflA pflA pflB pflB pflB-2 pflB-2 pckA pckA gpmI gpmI tpiA tpiA glpX glpX aceK aceK pgi pgi fbp fbp yjjW yjjW
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EHY70161.1Glyceraldehyde-3-phosphate dehydrogenase, type I; KEGG: sek:SSPA1445 3.4e-174 glyceraldehyde 3-phosphate dehydrogenase A; K00134 glyceraldehyde 3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 10.00; locus tag in AE006468 is STM1290; gapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
EHY70772.1L-serine ammonia-lyase; KEGG: spq:SPAB_01388 7.4e-243 hypothetical protein; K01752 L-serine dehydratase; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1826; sdaA. (454 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa)
hycDNADH dehydrogenase; Locus tag in AE006468 is STM2850; hycD. (307 aa)
hycB4Fe-4S binding domain protein; Locus tag in AE006468 is STM2852; hycB. (202 aa)
sdaBKEGG: see:SNSL254_A3194 1.2e-240 L-serine ammonia-lyase K01752; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM2971; sdaB; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
gapAD-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (342 aa)
tdcGKEGG: sek:SSPA2901 4.0e-235 L-serine dehydratase; K01752 L-serine dehydratase; locus tag in AE006468 is STM3240; tdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa)
gpmAPhosphoglycerate mutase 1 family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa)
pglPutative 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa)
EHY69739.1Pyruvate formate-lyase; KEGG: sea:SeAg_B0884 0. formate C-acetyltransferase 3 K00656; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0843; pflF. (810 aa)
EHY69740.1Glycyl-radical enzyme activating family protein; KEGG: seg:SG0825 7.1e-158 pflE; putative pyruvate formate-lyase 3 activating enzyme K04069; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0844; pflE. (299 aa)
pflAPyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (277 aa)
pflBFormate acetyltransferase; KEGG: spq:SPAB_02545 0. hypothetical protein; K00656 formate C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0973; pflB. (760 aa)
pflB-2Formate acetyltransferase; KEGG: spq:SPAB_04044 0. hypothetical protein; K00656 formate C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3241; tdcE. (764 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (539 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
glpXFructose-1,6-bisphosphatase, class II; KEGG: stt:t3533 2.1e-167 glpX; fructose 1,6-bisphosphatase II K02446; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM4085; glpX. (325 aa)
aceK[isocitrate dehydrogenase (NADP(+))] kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (583 aa)
pgiGlucose-6-phosphate isomerase; Locus tag in AE006468 is STM4221; pgi; Belongs to the GPI family. (549 aa)
fbpFructose-1,6-bisphosphatase; Locus tag in AE006468 is STM4415; fbp; Belongs to the FBPase class 1 family. (332 aa)
yjjWRadical SAM domain protein; Locus tag in AE006468 is STM4565; yjjW. (244 aa)
Your Current Organism:
Salmonella enterica houtenae
NCBI taxonomy Id: 523831
Other names: S. enterica subsp. houtenae str. ATCC BAA-1581, Salmonella enterica subsp. houtenae str. ATCC BAA-1581
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