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| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) |
| | rplQ | Ribosomal protein L17; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3414; rplQ. (128 aa) |
| | rpsD | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (154 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (103 aa) |
| | rplO | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | rpmD | Ribosomal protein L30; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3422; rpmD. (59 aa) |
| | rplR | Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (167 aa) |
| | rplF | Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rpsH | Ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rpsN | Ribosomal protein S14p/S29e; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (96 aa) |
| | rplE | Ribosomal L5P family protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rplX | Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa) |
| | rplN | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (104 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rpmC | Ribosomal protein L29; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3432; rpmC; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | rplP | Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpsC | Ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (233 aa) |
| | rplV | Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa) |
| | rpsS | 30S ribosomal protein S19 domain protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (49 aa) |
| | rplB | Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) |
| | rplW | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplD | Ribosomal protein L4/L1 family protein; Forms part of the polypeptide exit tunnel. (201 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | rpsJ | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | tuf | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | fusA | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (704 aa) |
| | rpsG | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsL | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa) |
| | trpS | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa) |
| | EHY67907.1 | Hypothetical protein; KEGG: gox:GOX1717 1.4e-05 putative oxidoreductase K07007; locus tag in AE006468 is STM3588; yhiN. (398 aa) |
| | glyS | KEGG: stm:STM3655 0. glyS; glycyl-tRNA synthetase subunit beta K01879; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3655; glyS. (689 aa) |
| | glyQ | KEGG: set:SEN3478 1.9e-166 glyQ; glycyl-tRNA synthetase subunit alpha K01878; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3656; glyQ. (303 aa) |
| | selB | KEGG: eci:UTI89_C4132 1.7e-284 selB; selenocysteinyl-tRNA-specific translation factor K03833; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3682; selB. (616 aa) |
| | selA_2 | L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa) |
| | rpmG | Ribosomal protein L33; KEGG: mmo:MMOB5490 0.0011 rpmG; 50S ribosomal protein L33 K02913; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3727; rpmG; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | rpmB | Ribosomal protein L28; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3728; rpmB; Belongs to the bacterial ribosomal protein bL28 family. (66 aa) |
| | rpmH | Ribosomal protein L34; KEGG: rak:A1C_04775 2.3e-10 rpmH; 50S ribosomal protein L34 K02914; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3839; rpmH; Belongs to the bacterial ribosomal protein bL34 family. (46 aa) |
| | rpmE | Ribosomal protein L31; Binds the 23S rRNA. (70 aa) |
| | EHY67118.1 | KEGG: stt:t4060 6.7e-210 tuf; elongation factor Tu K02358; Psort location: Cytoplasmic, score: 9.97. (394 aa) |
| | rplK | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (126 aa) |
| | rplA | Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | rplJ | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | rplL | Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa) |
| | efp | Translation elongation factor P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | epmA | lysyl-tRNA synthetase-like protein GenX; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta- lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF- P 'Lys-34'; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (325 aa) |
| | rpsF | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (131 aa) |
| | rpsR | Ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rplI | Ribosomal protein L9; Binds to the 23S rRNA. (149 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa) |
| | trpS-2 | tryptophan--tRNA ligase; Locus tag in AE006468 is STM4508; trpS2; Belongs to the class-I aminoacyl-tRNA synthetase family. (337 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | yjjK | ABC transporter, ATP-binding protein YjiK; Locus tag in AE006468 is STM4581; yjjK. (555 aa) |
| | rpsT | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. (61 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (956 aa) |
| | gluQ | glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (313 aa) |
| | rpsB | Ribosomal protein S2; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0216; rpsB; Belongs to the universal ribosomal protein uS2 family. (236 aa) |
| | tsf | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (283 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | yaeJ | KEGG: reh:H16_A3611 6.3e-31 pth2; peptidyl-tRNA hydrolase K05969; locus tag in AE006468 is STM0240; yaeJ. (140 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (572 aa) |
| | rpmE2 | Ribosomal protein L31; KEGG: ckp:ckrop_0375 0.0042 putative glutathione peroxidase; K00432 glutathione peroxidase; locus tag in AE006468 is STM0469; rpmE2. (86 aa) |
| | ybaK | YbaK/ebsC protein; KEGG: ent:Ent638_0960 2.3e-72 hypothetical protein; locus tag in AE006468 is STM0495; ybaK; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (159 aa) |
| | cysS | cysteinyl-tRNA synthetase; KEGG: see:SNSL254_A0590 1.1e-250 cysS; cysteinyl tRNA synthetase K01883; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0537; cysS; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (642 aa) |
| | rpmF | Ribosomal protein L32; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1191; rpmF; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) |
| | EHY69913.1 | KEGG: pmu:PM1115 2.5e-132 gltX; glutamyl-tRNA synthetase K01885; Psort location: Cytoplasmic, score: 9.97. (465 aa) |
| | asnS | KEGG: sea:SeAg_B1008 2.1e-236 asnC; asparaginyl-tRNA synthetase K01893; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1000; asnS. (441 aa) |
| | rpsA | Ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (557 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | rimK | alpha-L-glutamate ligase, RimK family; Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF). Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate. The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH. (300 aa) |
| | glnS | KEGG: sew:SeSA_A0841 0. glnS; glutaminyl-tRNA synthetase K01886; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0686; glnS. (555 aa) |
| | leuS | KEGG: ses:SARI_02284 0. leuS; leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM0648; leuS; Belongs to the class-I aminoacyl-tRNA synthetase family. (860 aa) |
| | ybcJ | Hypothetical protein; Locus tag in AE006468 is STM0541; ybcJ. (70 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (113 aa) |
| | rpmI | Ribosomal protein L35; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1335; rpmI; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | rplT | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | pheS | KEGG: sek:SSPA1398 3.4e-174 phenylalanyl-tRNA synthetase alpha chain; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1337; pheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (327 aa) |
| | pheT | KEGG: set:SEN1706 0. pheT; phenylalanyl-tRNA synthetase subunit beta K01890; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM1338; pheT. (795 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | sra | 30S ribosomal subunit S22; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM1565; rpsV. (47 aa) |
| | EHY70559.1 | B3/4 domain protein; KEGG: mse:Msed_2004 5.6e-07 phosphoenolpyruvate synthase; locus tag in AE006468 is STM1665. (228 aa) |
| | yciH | Putative translation initiation factor SUI1; Psort location: Cytoplasmic, score: 8.96; locus tag in AE006468 is STM1706; yciH. (108 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (194 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa) |
| | argS | arginyl-tRNA synthetase; Locus tag in AE006468 is STM1909; argS. (577 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (704 aa) |
| | yeiP | Elongation factor P; KEGG: bpu:BPUM_2177 4.3e-25 efp; elongation factor P K02356; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2211; yeiP. (190 aa) |
| | rplY | Ribosomal L25p family protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa) |
| | hisS | KEGG: stm:STM2522 7.6e-225 hisS; histidyl-tRNA synthetase K01892; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM2522; hisS. (424 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (556 aa) |
| | rplS | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | rpsP | Ribosomal protein S16; Locus tag in AE006468 is STM2676; rpsP; Belongs to the bacterial ribosomal protein bS16 family. (82 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (175 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (876 aa) |
| | lysS | lysyl-tRNA synthetase; KEGG: stm:STM3040 5.5e-270 lysS; lysyl-tRNA synthetase K04567; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3040; lysS; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (293 aa) |
| | rpsU | Ribosomal protein S21; KEGG: sew:SeSA_A3399 2.7e-32 rpsU; 30S ribosomal protein S21 K02970; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3209; rpsU; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | rpsO | Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (58 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (892 aa) |
| | rpmA | Ribosomal protein L27; Psort location: Cytoplasmic, score: 9.26; locus tag in AE006468 is STM3303; rpmA; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | rpsI | Ribosomal protein S9; Psort location: Cytoplasmic, score: 9.97; locus tag in AE006468 is STM3344; rpsI; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa) |
